Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI - Wikidata - wikimedia - TriplyDB

Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI

Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI

http://www.wikidata.org/entity/Q37071138

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Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo Future prospects for contact factors as therapeutic targets Factor XI as a target for antithrombotic therapy Factor XI and contact activation as targets for antithrombotic therapy Microfluidics and coagulation biology A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo Structure and function of factor XI A factor XIIa inhibitory antibody provides thromboprotection in extracorporeal circulation without increasing bleeding risk.Designing allosteric inhibitors of factor XIa. Lessons from the interactions of sulfated pentagalloylglucopyranosides.Factor XI antisense oligonucleotide for prevention of venous thrombosis.Laminin promotes coagulation and thrombus formation in a factor XII-dependent manner.Blood clot formation under flow: the importance of factor XI depends strongly on platelet count.Safety and antithrombotic efficacy of moderate platelet count reduction by thrombopoietin inhibition in primates.Inhibition of factor XI activation attenuates inflammation and coagulopathy while improving the survival of mouse polymicrobial sepsis FXIa and platelet polyphosphate as therapeutic targets during human blood clotting on collagen/tissue factor surfaces under flow Factor XIa and Thrombin Generation Are Elevated in Patients with Acute Coronary Syndrome and Predict Recurrent Cardiovascular Events The role of carrier number on the procoagulant activity of tissue factor in blood and plasma.P1 and P2' site mutations convert protease nexin-2 from a factor XIa inhibitor to a plasmin inhibitor Coagulation Factor XI Promotes Distal Platelet Activation and Single Platelet Consumption in the Bloodstream Under Shear Flow.A comparison of the effects of factor XII deficiency and prekallikrein deficiency on thrombus formation.Physiological levels of blood coagulation factors IX and X control coagulation kinetics in an in vitro model of circulating tissue factor.Factor XII promotes blood coagulation independent of factor XI in the presence of long-chain polyphosphates.Factor XI as a Therapeutic Target.Factor XIa inhibitors: A review of the patent literature.Factor XI contributes to thrombin generation in the absence of factor XII Antisense technology: an emerging platform for cardiovascular disease therapeutics.Identification of coagulation factor XI as a ligand for platelet apolipoprotein E receptor 2 (ApoER2).Factor XII inhibition reduces thrombus formation in a primate thrombosis model.Factors XI and XII as Targets for New Anticoagulants.Coagulation factor XI as a novel target for antithrombotic treatment.The many faces of the contact pathway and their role in thrombosis.Factor XI and XII as antithrombotic targets.Medical device-induced thrombosis: what causes it and how can we prevent it?The Intrinsic Pathway of Coagulation as a Target for Antithrombotic Therapy.Genome-wide association study with additional genetic and post-transcriptional analyses reveals novel regulators of plasma factor XI levels.Utility of microfluidic devices to study the platelet-endothelium interface.Development of coagulation factor probes for the identification of procoagulant circulating tumor cells.Colocalization of neutrophils, extracellular DNA and coagulation factors during NETosis: Development and utility of an immunofluorescence-based microscopy platform.Inhibition of Factor XII-Mediated Activation of Factor XI Provides Protection Against Experimental Acute Ischemic Stroke in Mice.Selective depletion of plasma prekallikrein or coagulation factor XII inhibits thrombosis in mice without increased risk of bleeding.

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Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI

http://www.wikidata.org/entity/Q37071138

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 22 October 2008

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Prevention of vascular graft o ...... ion by inhibition of factor XI

@en

Prevention of vascular graft o ...... on by inhibition of factor XI.

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type

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Prevention of vascular graft o ...... ion by inhibition of factor XI

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Prevention of vascular graft o ...... on by inhibition of factor XI.

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Prevention of vascular graft o ...... ion by inhibition of factor XI

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Prevention of vascular graft o ...... on by inhibition of factor XI.

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Prevention of vascular graft o ...... ion by inhibition of factor XI

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András Gruber

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David Gailani

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Erik I Tucker

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Owen J T McCarty

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Sandra Rugonyi

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Sawan Hurst

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Stephen R Hanson

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Tara C White

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Ulla M Marzec

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P2860

Defective thrombus formation in mice lacking coagulation factor XII

Recombinant nematode anticoagulant protein c2, an inhibitor of the tissue factor/factor VIIa complex, in patients undergoing elective coronary angioplasty

Effects of factor IX or factor XI deficiency on ferric chloride-induced carotid artery occlusion in mice

TAFI, or plasma procarboxypeptidase B, couples the coagulation and fibrinolytic cascades through the thrombin-thrombomodulin complex

Coagulation-dependent inhibition of fibrinolysis: role of carboxypeptidase-U and the premature lysis of clots from hemophilic plasma

Synthesis and properties of peptidyl derivatives of arginylfluoromethanes

Platelet near-wall excess in porcine whole blood in artery-sized tubes under steady and pulsatile flow conditions.

Rare coagulation disorders.

Antithrombotic effects of thrombin-induced activation of endogenous protein C in primates.

Factor XI deficiency in Ashkenazi Jews in Israel.

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936-944

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10.1182/BLOOD-2008-06-163675

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2630279

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