about
Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinaseA Comprehensive and System Review for the Pharmacological Mechanism of Action of Rhein, an Active Anthraquinone IngredientIntegration of protein kinases mTOR and extracellular signal-regulated kinase 5 in regulating nucleocytoplasmic localization of NFATc4The translation regulatory subunit eIF3f controls the kinase-dependent mTOR signaling required for muscle differentiation and hypertrophy in mouse.Dynamic switch of negative feedback regulation in Drosophila Akt-TOR signaling.PIK3CA mutations in in situ and invasive breast carcinomas.Human chorionic gonadotropin stimulates theca-interstitial cell proliferation and cell cycle regulatory proteins by a cAMP-dependent activation of AKT/mTORC1 signaling pathwayDiet and energy-sensing inputs affect TorC1-mediated axon misrouting but not TorC2-directed synapse growth in a Drosophila model of tuberous sclerosis.Elevated corticosterone associated with food deprivation upregulates expression in rat skeletal muscle of the mTORC1 repressor, REDD1.Expression of insulin-like growth factor I receptor as a biomarker for predicting prognosis in biliary tract cancer patientsPI3K Pathway in NSCLCPI3 K/Akt/mTOR-mediated translational control regulates proliferation and differentiation of lineage-restricted RoSH stem cell lines.PI3K expression and PIK3CA mutations are related to colorectal cancer metastases.Baculovirus-mediated expression, purification, and characterization of a fully activated catalytic kinase domain construct of the 70 kDa 40S ribosomal protein S6 kinase-1 alphaII isoform (S6K1alphaII).Expression, purification, and characterization of a structurally disordered and functional C-terminal autoinhibitory domain (AID) of the 70 kDa 40S ribosomal protein S6 kinase-1 (S6K1).Future anti-catabolic therapeutic targets in bone disease.Targeting mTOR in HIV-Negative Classic Kaposi's Sarcoma.S6 kinase 2 potentiates interleukin-3-driven cell proliferationRAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation.Regulation of catalytic activity of S6 kinase 2 during cell cycleJujuboside A Protects H9C2 Cells from Isoproterenol-Induced Injury via Activating PI3K/Akt/mTOR Signaling PathwayThe Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor: Lessons on dysregulated angiogenesis from a viral oncogene.Activation of signaling pathways and regulatory mechanisms of mRNA translation following myocardial ischemia-reperfusion.Portal infusion of amino acids is more efficient than peripheral infusion in stimulating liver protein synthesis at the same hepatic amino acid load in dogsCharacterization of pomiferin triacetate as a novel mTOR and translation inhibitorTime now to TORC the TORC? New developments in mTOR pathway inhibition in lymphoid malignancies.Dexamethasone represses signaling through the mammalian target of rapamycin in muscle cells by enhancing expression of REDD1.Signal transduction in cancerMolecular mechanisms of cell death in intervertebral disc degeneration (Review).Effects of PI3K inhibitor NVP-BKM120 on acquired resistance to gefitinib of human lung adenocarcinoma H1975 cells.Lactobacillus casei extract induces apoptosis in gastric cancer by inhibiting NF-κB and mTOR-mediated signaling.Regulation and Modulation of Human DNA Polymerase δ Activity and Function.Activation of mammalian target of rapamycin signaling promotes cell cycle progression and protects cells from apoptosis in mantle cell lymphoma.Signal transduction molecules in gliomas of all grades.Elevated plasma free fatty acids decrease basal protein synthesis, but not the anabolic effect of leucine, in skeletal muscle.The p85beta regulatory subunit of phosphoinositide 3-kinase has unique and redundant functions in B cellsSHP-2 regulates cell growth by controlling the mTOR/S6 kinase 1 pathway.Kinetic mechanism of fully activated S6K1 protein kinase.Novel pathway in Bcr-Abl signal transduction involves Akt-independent, PLC-gamma1-driven activation of mTOR/p70S6-kinase pathway.Modulation of specific protein expression levels by PTEN: identification of AKAP121, DHFR, G3BP, Rap1, and RCC1 as potential targets of PTEN.
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
PI3-kinase and TOR: PIKTORing cell growth.
@ast
PI3-kinase and TOR: PIKTORing cell growth.
@en
type
label
PI3-kinase and TOR: PIKTORing cell growth.
@ast
PI3-kinase and TOR: PIKTORing cell growth.
@en
prefLabel
PI3-kinase and TOR: PIKTORing cell growth.
@ast
PI3-kinase and TOR: PIKTORing cell growth.
@en
P2093
P1476
PI3-kinase and TOR: PIKTORing cell growth.
@en
P2093
Celeste J Richardson
John Blenis
Stefanie S Schalm
P304
P356
10.1016/J.SEMCDB.2003.12.023
P577
2004-04-01T00:00:00Z