Dexamethasone represses signaling through the mammalian target of rapamycin in muscle cells by enhancing expression of REDD1.
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Multifaceted role of insulin-like growth factors and mammalian target of rapamycin in skeletal muscleInflammatory Bowel Disease Drugs: A Focus on AutophagyREDD1 is a major target of testosterone action in preventing dexamethasone-induced muscle lossDexamethasone modulates ErbB tyrosine kinase expression and signaling through multiple and redundant mechanisms in cultured rat hepatocytesSteroid and oxygen effects on eIF4F complex, mTOR, and ENaC translation in fetal lung epitheliaEpithelial-specific deletion of 11β-HSD2 hinders Apcmin/+ mouse tumorigenesis.mRNA-seq reveals skeletal muscle atrophy in response to handling stress in a marine teleost, the red cusk-eel (Genypterus chilensis)REDD1 is essential for stress-induced synaptic loss and depressive behavior.Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatasesDifferential alterations in gene expression profiles contribute to time-dependent effects of nandrolone to prevent denervation atrophy.The effects of omega-3 fatty acid supplementation on dexamethasone-induced muscle atrophy.Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance.Altered nutrient response of mTORC1 as a result of changes in REDD1 expression: effect of obesity vs. REDD1 deficiency.Control of translation initiation through integration of signals generated by hormones, nutrients, and exerciseChronic α-hydroxyisocaproic acid treatment improves muscle recovery after immobilization-induced atrophy.Effects of cortisol and dexamethasone on insulin signalling pathways in skeletal muscle of the ovine fetus during late gestation.The stress-response gene redd1 regulates dorsoventral patterning by antagonizing Wnt/β-catenin activity in zebrafishAtomoxetine prevents dexamethasone-induced skeletal muscle atrophy in miceElevated corticosterone associated with food deprivation upregulates expression in rat skeletal muscle of the mTORC1 repressor, REDD1.REDD1 functions at the crossroads between the therapeutic and adverse effects of topical glucocorticoidsMetabolite and transcriptome analysis during fasting suggest a role for the p53-Ddit4 axis in major metabolic tissuesThe regulation of muscle mass by endogenous glucocorticoids.REDD1 (regulated in development and DNA damage response 1) expression in skeletal muscle as a surrogate biomarker of the efficiency of glucocorticoid receptor blockade.Glucocorticoid elevation of dexamethasone-induced gene 2 (Dig2/RTP801/REDD1) protein mediates autophagy in lymphocytes.Dexamethasone and BCAA Failed to Modulate Muscle Mass and mTOR Signaling in GH-Deficient RatsCentral nervous system inflammation induces muscle atrophy via activation of the hypothalamic-pituitary-adrenal axis.REDD1 Is Essential for Optimal T Cell Proliferation and Survival.Regulation of REDD1 by insulin-like growth factor-I in skeletal muscle and myotubes.A cell-autonomous role for the glucocorticoid receptor in skeletal muscle atrophy induced by systemic glucocorticoid exposure.In utero glucocorticoid exposure reduces fetal skeletal muscle mass in rats independent of effects on maternal nutrition.Genome-wide analysis of glucocorticoid receptor-binding sites in myotubes identifies gene networks modulating insulin signaling.Dietary intervention in acne: Attenuation of increased mTORC1 signaling promoted by Western diet.Aberrant REDD1-mTORC1 responses to insulin in skeletal muscle from Type 2 diabeticsThe impact of cow's milk-mediated mTORC1-signaling in the initiation and progression of prostate cancerTestosterone regulation of Akt/mTORC1/FoxO3a signaling in skeletal muscle.The mTORC1 signaling repressors REDD1/2 are rapidly induced and activation of p70S6K1 by leucine is defective in skeletal muscle of an immobilized rat hindlimb.Acyl-CoA synthetase-4, a new regulator of mTOR and a potential therapeutic target for enhanced estrogen receptor function in receptor-positive and -negative breast cancerRole of Akt/GSK-3beta/beta-catenin transduction pathway in the muscle anti-atrophy action of insulin-like growth factor-I in glucocorticoid-treated rats.A gene signature-based approach identifies mTOR as a regulator of p73.Calpain activity and muscle wasting in sepsis
P2860
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P2860
Dexamethasone represses signaling through the mammalian target of rapamycin in muscle cells by enhancing expression of REDD1.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Dexamethasone represses signal ...... enhancing expression of REDD1.
@en
type
label
Dexamethasone represses signal ...... enhancing expression of REDD1.
@en
prefLabel
Dexamethasone represses signal ...... enhancing expression of REDD1.
@en
P2093
P2860
P356
P1476
Dexamethasone represses signal ...... enhancing expression of REDD1.
@en
P2093
Hongmei Wang
Leif W Ellisen
Leonard S Jefferson
Neil Kubica
Scot R Kimball
P2860
P304
39128-39134
P356
10.1074/JBC.M610023200
P407
P577
2006-10-30T00:00:00Z