Functional implications of genetic polymorphisms in the multidrug resistance gene MDR1 (ABCB1).
about
Function-altering SNPs in the human multidrug transporter gene ABCB1 identified using a Saccharomyces-based assayPrediction by graph theoretic measures of structural effects in proteins arising from non-synonymous single nucleotide polymorphisms.Modulation of human placental P-glycoprotein expression and activity by MDR1 gene polymorphisms.ABCB1 genetic variants in leukemias: current insights into treatment outcomesCentral neurotoxicity in cancer chemotherapy: pharmacogenetic insights.ATP-binding cassette efflux transporters in human placenta.ABCB1 (rs1128503) polymorphism and response to chemotherapy in patients with malignant tumors-evidences from a meta-analysis.A novel human multidrug resistance gene MDR1 variant G571A (G191R) modulates cancer drug resistance and efflux transportPharmacogenomics of drug metabolizing enzymes and transporters: implications for cancer therapy.Searching for polymorphisms that affect gene expression and mRNA processing: example ABCB1 (MDR1).PhRMA white paper on ADME pharmacogenomics.P-glycoprotein related drug interactions: clinical importance and a consideration of disease states.Pharmacogenetics of drug transporters in the enterohepatic circulation.Pharmacogenetics and individualized therapy in children: immunosuppressants, antidepressants, anticancer and anti-inflammatory drugs.Clinical impact of genetic variants of drug transporters in different ethnic groups within and across regions.Genetic markers for prediction of treatment outcomes in ovarian cancer.ABCB1 haplotypes but not individual SNPs predict for optimal response/failure in Egyptian patients with chronic-phase chronic myeloid leukemia receiving imatinib mesylate.Population pharmacokinetic analysis of rebamipide in healthy Korean subjects with the characterization of atypical complex absorption kinetics.Substrate-dependent effects of human ABCB1 coding polymorphismsBerry anthocyanins and anthocyanidins exhibit distinct affinities for the efflux transporters BCRP and MDR1.Do drug transporter (ABCB1) SNPs and P-glycoprotein function influence cyclosporine and macrolides exposure in renal transplant patients? Results of the pharmacogenomic substudy within the symphony study.Polymorphisms of the MDR1 and MIF genes in children with nephrotic syndrome.Evolutionarily Conserved Roles for Blood-Brain Barrier Xenobiotic Transporters in Endogenous Steroid Partitioning and Behavior.A MDR1 (ABCB1) gene single nucleotide polymorphism predicts outcome of temozolomide treatment in glioblastoma patients.Differential effect of ABCB1 haplotypes on promoter activity.Enhanced anti-tumor efficacy and mechanisms associated with docetaxel-piperine combination- in vitro and in vivo investigation using a taxane-resistant prostate cancer model.Determination of ABCB1 polymorphisms and haplotypes frequencies in a French populationG2677T and C3435T Genotype and Haplotype Are Associated With HepaticABCB1(MDR1) Expression
P2860
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P2860
Functional implications of genetic polymorphisms in the multidrug resistance gene MDR1 (ABCB1).
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Functional implications of gen ...... resistance gene MDR1 (ABCB1).
@ast
Functional implications of gen ...... resistance gene MDR1 (ABCB1).
@en
type
label
Functional implications of gen ...... resistance gene MDR1 (ABCB1).
@ast
Functional implications of gen ...... resistance gene MDR1 (ABCB1).
@en
prefLabel
Functional implications of gen ...... resistance gene MDR1 (ABCB1).
@ast
Functional implications of gen ...... resistance gene MDR1 (ABCB1).
@en
P1476
Functional implications of gen ...... resistance gene MDR1 (ABCB1).
@en
P2093
Christiane Pauli-Magnus
Deanna L Kroetz
P304
P356
10.1023/B:PHAM.0000029276.21063.0B
P577
2004-06-01T00:00:00Z