Tumor-derived autophagosome vaccine: induction of cross-protective immune responses against short-lived proteins through a p62-dependent mechanism. - Wikidata - wikimedia - TriplyDB

Tumor-derived autophagosome vaccine: induction of cross-protective immune responses against short-lived proteins through a p62-dependent mechanism.

Tumor-derived autophagosome vaccine: induction of cross-protective immune responses against short-lived proteins through a p62-dependent mechanism.

http://www.wikidata.org/entity/Q35816796

about

Glimpse into the future: harnessing autophagy to promote anti-tumor immunity with the DRibbles vaccine Nanomaterials and autophagy: new insights in cancer treatment Coupling of HIV-1 Antigen to the Selective Autophagy Receptor SQSTM1/p62 Promotes T-Cell-Mediated Immunity Cross-presentation of viral antigens in dribbles leads to efficient activation of virus-specific human memory T cells Trial Watch: Toll-like receptor agonists in oncological indications.Trial watch: Immunostimulatory cytokines in cancer therapy.Therapeutic antitumor efficacy of B cells loaded with tumor-derived autophagasomes vaccine (DRibbles)Tumor-derived autophagosomes (DRibbles) induce B cell activation in a TLR2-MyD88 dependent manner.An autophagosome-based therapeutic vaccine for HBV infection: a preclinical evaluation.Immunological significance of the accumulation of autophagy components in oral squamous cell carcinoma.Therapeutic antitumor efficacy of tumor-derived autophagosome (DRibble) vaccine on head and neck cancer.STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.Ubiquitinated proteins enriched from tumor cells by a ubiquitin binding protein Vx3(A7) as a potent cancer vaccine.Of LAP, CUPS, and DRibbles - Unconventional Use of Autophagy Proteins for MHC Restricted Antigen Presentation Increasing the efficacy of tumor cell vaccines by enhancing cross priming Multiple vaccinations: friend or foe.Tumor-released autophagosomes induce IL-10-producing B cells with suppressive activity on T lymphocytes via TLR2-MyD88-NF-κB signal pathway.Future perspectives in melanoma research : Meeting report from the "Melanoma Bridge". Napoli, December 1st-4th 2015.Combinational Immunotherapy with Allo-DRibble Vaccines and Anti-OX40 Co-Stimulation Leads to Generation of Cross-Reactive Effector T Cells and Tumor Regression.Translating DRiPs: MHC class I immunosurveillance of pathogens and tumors.The Autophagic Machinery in Viral Exocytosis.The impact of macroautophagy on CD8(+) T-cell-mediated antiviral immunity.Autophagy as a Stress Response Pathway in the Immune System.Inflammatory Signaling Cascades and Autophagy in Cancer.Autophagy proteins in antigen processing for presentation on MHC molecules.Microbial HSP70 peptide epitope 407-426 as adjuvant in tumor-derived autophagosome vaccine therapy of mouse lung cancer.TLR and NLRP3 inflammasome-dependent innate immune responses to tumor-derived autophagosomes (DRibbles).Sorafenib and a novel immune therapy in lung metastasis from hepatocellular carcinoma following hepatectomy: A case report.Immune responses of dendritic cells combined with tumor-derived autophagosome vaccine on hepatocellular carcinoma.Autophagy-assisted antigen cross-presentation: Autophagosome as the argo of shared tumor-specific antigens and DAMPs.Autophagy Proteins in Phagocyte Endocytosis and Exocytosis Is immunity in cancer the key to improving clinical outcome?: Report on the International Symposium on Immunotherapy, The Royal Society, London, UK, 12-13 May 2017.Future perspectives in melanoma research. Meeting report from the "Melanoma Bridge. Napoli, December 2nd-4th 2012".A pilot study of an autologous tumor-derived autophagosome vaccine with docetaxel in patients with stage IV non-small cell lung cancer.Necroptosis promotes autophagy-dependent upregulation of DAMP and results in immunosurveillance.Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination.Perspectives in immunotherapy: meeting report from the Immunotherapy Bridge (29-30 November, 2017, Naples, Italy).

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P2860

Tumor-derived autophagosome vaccine: induction of cross-protective immune responses against short-lived proteins through a p62-dependent mechanism.

http://www.wikidata.org/entity/Q35816796

description

2011 nî lūn-bûn

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name

Tumor-derived autophagosome va ...... ugh a p62-dependent mechanism.

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Tumor-derived autophagosome va ...... ugh a p62-dependent mechanism.

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type

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Tumor-derived autophagosome va ...... ugh a p62-dependent mechanism.

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Tumor-derived autophagosome va ...... ugh a p62-dependent mechanism.

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Tumor-derived autophagosome va ...... ugh a p62-dependent mechanism.

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Tumor-derived autophagosome va ...... ugh a p62-dependent mechanism.

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Clinical Cancer Research

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Tumor-derived autophagosome va ...... ugh a p62-dependent mechanism.

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P2093

Bernard A Fox

http://www.w3.org/2001/XMLSchema#string

Christopher G Twitty

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Hong-Ming Hu

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Shawn M Jensen

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P2860

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

A role for NBR1 in autophagosomal degradation of ubiquitinated substrates

Autophagy suppresses tumorigenesis through elimination of p62

Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion.

In vivo half-life of a protein is a function of its amino-terminal residue

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

Membrane vesicles as conveyors of immune responses

Tumor-derived microvesicles induce, expand and up-regulate biological activities of human regulatory T cells (Treg).

The makings of a tumor rejection antigen.

Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay.

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