STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors. - Wikidata - wikimedia - TriplyDB

STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.

STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.

http://www.wikidata.org/entity/Q35263440

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Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.Tumor-intrinsic oncogene pathways mediating immune avoidance Vaccine adjuvants as potential cancer immunotherapeutics Improving the clinical impact of biomaterials in cancer immunotherapy.STING: infection, inflammation and cancer To Extinguish the Fire from Outside the Cell or to Shutdown the Gas Valve Inside? Novel Trends in Anti-Inflammatory Therapies The Next Hurdle in Cancer Immunotherapy: Overcoming the Non-T-Cell-Inflamed Tumor Microenvironment Control of CD8 T-Cell Infiltration into Tumors by Vasculature and Microenvironment The STING pathway and the T cell-inflamed tumor microenvironment Dendritic cell-based vaccination in cancer: therapeutic implications emerging from murine models Targeting the innate immune system as immunotherapy for acute myeloid leukemia Adjuvants for peptide-based cancer vaccines DNA sensor cGAS-mediated immune recognition The Impact of Chemotherapy, Radiation and Epigenetic Modifiers in Cancer Cell Expression of Immune Inhibitory and Stimulatory Molecules and Anti-Tumor Efficacy Molecular Pathways: Targeting the Stimulator of Interferon Genes (STING) in the Immunotherapy of Cancer Innate immune recognition of DNA: A recent history Harnessing the Power of Onco-Immunotherapy with Checkpoint Inhibitors Apoptotic cell responses in the splenic marginal zone: a paradigm for immunologic reactions to apoptotic antigens with implications for autoimmunity Involvement of GATA1 and Sp3 in the activation of the murine STING gene promoter in NIH3T3 cells.Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer.DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity.IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance Characterization of the immunophenotypes and antigenomes of colorectal cancers reveals distinct tumor escape mechanisms and novel targets for immunotherapy.Effective and lesion-free cutaneous influenza vaccination Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity.Cell Free DNA of Tumor Origin Induces a 'Metastatic' Expression Profile in HT-29 Cancer Cell Line.Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy.Tumor and Host Factors Controlling Antitumor Immunity and Efficacy of Cancer Immunotherapy.Radiation takes its Toll CD47 blockade triggers T cell-mediated destruction of immunogenic tumors.Akt Kinase-Mediated Checkpoint of cGAS DNA Sensing Pathway SENP7 Potentiates cGAS Activation by Relieving SUMO-Mediated Inhibition of Cytosolic DNA Sensing.The E3 ubiquitin ligase RNF185 facilitates the cGAS-mediated innate immune response.STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity.Radiotherapy Combined with Novel STING-Targeting Oligonucleotides Results in Regression of Established Tumors.Antitumor Activity of cGAMP via Stimulation of cGAS-cGAMP-STING-IRF3 Mediated Innate Immune Response.Immunosurveillance and immunotherapy of tumors by innate immune cells.Antagonism of the STING Pathway via Activation of the AIM2 Inflammasome by Intracellular DNA.STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation.Inflammatory Signals Regulate IL-15 in Response to Lymphodepletion.

P2860

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P2860

STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.

http://www.wikidata.org/entity/Q35263440

description

2014 nî lūn-bûn

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2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

STING-dependent cytosolic DNA ...... gnition of immunogenic tumors.

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STING-dependent cytosolic DNA ...... gnition of immunogenic tumors.

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type

label

STING-dependent cytosolic DNA ...... gnition of immunogenic tumors.

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STING-dependent cytosolic DNA ...... gnition of immunogenic tumors.

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prefLabel

STING-dependent cytosolic DNA ...... gnition of immunogenic tumors.

@ast

STING-dependent cytosolic DNA ...... gnition of immunogenic tumors.

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J.IMMUNI.2014.10.017

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STING-dependent cytosolic DNA ...... ognition of immunogenic tumors

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Glen N Barber

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Katherine A Fitzgerald

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Leticia Corrales

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Maria-Luisa Alegre

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Michael J Furdyna

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Michael Y K Leung

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Ryan Duggan

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Seng-Ryong Woo

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Stefani Spranger

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Thomas F Gajewski

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P2860

Recognition of damage-associated molecular patterns related to nucleic acids during inflammation and vaccination

IFI16 is an innate immune sensor for intracellular DNA

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome

Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

STING is a direct innate immune sensor of cyclic di-GMP

Type I interferon response and innate immune sensing of cancer

Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA

Type, density, and location of immune cells within human colorectal tumors predict clinical outcome

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830-842

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scholarly article

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10.1016/J.IMMUNI.2014.10.017

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5

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Mercedes Fuertes

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2014-11-05T00:00:00Z

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269765992

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25517615

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4384884

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