The mTOR Inhibitor Rapamycin Mitigates Perforant Pathway Neurodegeneration and Synapse Loss in a Mouse Model of Early-Stage Alzheimer-Type Tauopathy.
about
Therapeutic Targeting of AutophagyBiotic/Abiotic Stress-Driven Alzheimer's Disease.Long-term caloric restriction in ApoE-deficient mice results in neuroprotection via Fgf21-induced AMPK/mTOR pathway.Consumption of pomegranates improves synaptic function in a transgenic mice model of Alzheimer's disease.Rapamycin modulated brain-derived neurotrophic factor and B-cell lymphoma 2 to mitigate autism spectrum disorder in rats.PRAS40 alleviates neurotoxic prion peptide-induced apoptosis via mTOR-AKT signaling.Targeting mTOR to reduce Alzheimer-related cognitive decline: from current hits to future therapies.Caloric restriction: beneficial effects on brain aging and Alzheimer's disease.Neuroprotective effects of intrastriatal injection of rapamycin in a mouse model of excitotoxicity induced by quinolinic acid.A Brief Overview of Tauopathy: Causes, Consequences, and Therapeutic Strategies.Molecular Mechanisms Underlying the Anti-depressant Effects of Resveratrol: a Review.Secretory carrier membrane protein 5 is an autophagy inhibitor that promotes the secretion of α-synuclein via exosome.Hepatic S6K1 Partially Regulates Lifespan of Mice with Mitochondrial Complex I Deficiency.TNFα affects CREB-mediated neuroprotective signaling pathways of synaptic plasticity in neurons as revealed by proteomics and phospho-proteomics.Linking tuberous sclerosis complex, excessive mTOR signaling, and age-related neurodegeneration: a new association between TSC1 mutation and frontotemporal dementia.Caloric Restriction Mimetics Slow Aging of Neuromuscular Synapses and Muscle Fibers.PPAR Gamma Coactivator 1 Beta (PGC-1β) Reduces Mammalian Target of Rapamycin (mTOR) Expression via a SIRT1-Dependent Mechanism in Neurons.Axonal Degeneration in Tauopathies: Disease Relevance and Underlying Mechanisms.Dual mTORC1/mTORC2 blocker as a possible therapy for tauopathy in cellular model.Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndromeNeurodegenerative Diseases: Regenerative Mechanisms and Novel Therapeutic Approaches
P2860
Q28078117-CA868495-7582-48C8-A34A-A358D8D419EBQ37430445-C7C870E3-8C38-429D-8306-FD82A84473B7Q37538200-09532647-063A-4F23-B4EC-569095EC3BA5Q37662094-CC291BF4-2748-40CE-B49F-7E835B3C872CQ37720699-53B33FF2-4D0E-474D-AE36-4D5C76A37B96Q38712234-83925E17-134C-4527-B7FA-1D08872A8F74Q38815881-11F64D24-A457-4D54-90A7-862CE0EA3A49Q38848268-662CB8F9-DAF6-4124-BE3F-7F1CE56A75D8Q38988452-707F47D8-6D9A-4289-A6F9-45E793A566D1Q39270980-F9A45617-0783-469A-950E-A67FCA9B85CBQ39427752-D898E05C-20F3-45FB-A1D7-F251AC1B1958Q40995496-B362ED62-6967-4D8D-8DB9-111AA442D11DQ41623603-115E82FB-113F-47B0-BBD7-4B7E0619EF08Q41694180-622D90E3-74C5-4146-B2C2-65CBBE631FFBQ42657367-74916F11-620E-4502-ABCA-F6E9814E68F1Q45055374-12060C69-671B-4E6B-88D6-6688B2A103AAQ46489201-A62371C0-D287-4DC9-9280-8AAF6DD33373Q46985283-C5643F7E-607B-4BBA-B800-AE0BFE04B5AEQ47592140-33CF28BA-B86F-424D-AAA6-164C84FA6819Q58609012-5F4E6B22-4432-474F-88A9-CDB04A037D5BQ58737028-3D8D7386-7207-4781-ACA4-64D22E2CA749
P2860
The mTOR Inhibitor Rapamycin Mitigates Perforant Pathway Neurodegeneration and Synapse Loss in a Mouse Model of Early-Stage Alzheimer-Type Tauopathy.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
The mTOR Inhibitor Rapamycin M ...... tage Alzheimer-Type Tauopathy.
@ast
The mTOR Inhibitor Rapamycin M ...... tage Alzheimer-Type Tauopathy.
@en
type
label
The mTOR Inhibitor Rapamycin M ...... tage Alzheimer-Type Tauopathy.
@ast
The mTOR Inhibitor Rapamycin M ...... tage Alzheimer-Type Tauopathy.
@en
prefLabel
The mTOR Inhibitor Rapamycin M ...... tage Alzheimer-Type Tauopathy.
@ast
The mTOR Inhibitor Rapamycin M ...... tage Alzheimer-Type Tauopathy.
@en
P2093
P2860
P1433
P1476
The mTOR Inhibitor Rapamycin M ...... tage Alzheimer-Type Tauopathy.
@en
P2093
Robert Siman
Ryan Cocca
P2860
P304
P356
10.1371/JOURNAL.PONE.0142340
P407
P577
2015-11-05T00:00:00Z