Noninflammatory spongiform polioencephalomyelopathy caused by a neurotropic temperature-sensitive mutant of Moloney murine leukemia virus TB.
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Protection against murine leukemia virus-induced spongiform myeloencephalopathy in mice overexpressing Bcl-2 but not in mice deficient for interleukin-6, inducible nitric oxide synthetase, ICE, Fas, Fas ligand, or TNF-R1 genesOligodendrocytes are a major target of the toxicity of spongiogenic murine retroviruses.Development of physical forms of unintegrated retroviral DNA in mouse spinal cord tissue during ts1-induced spongiform encephalomyelopathy: elevated levels of a novel single-stranded form in paralyzed mice.Murine retroviral neurovirulence correlates with an enhanced ability ofvirus to infect selectively, replicate in, and activate resident microglial cellsInduction of focal spongiform neurodegeneration in developmentally resistant mice by implantation of murine retrovirus-infected microglia.Characterization of a neurologic disease induced by a polytropic murine retrovirus: evidence for differential targeting of ecotropic and polytropic viruses in the brainTwo separate envelope regions influence induction of brain disease by a polytropic murine retrovirus (FMCF98)Murine retrovirus-induced spongiform encephalopathy: disease expression is dependent on postnatal development of the central nervous system.Viral determinants that control the neuropathogenicity of PVC-211 murine leukemia virus in vivo determine brain capillary endothelial cell tropism of the virus in vitro.Site-directed mutagenesis of the codon for Ile-25 in gPr80env alters the neurovirulence of ts1, a mutant of Moloney murine leukemia virus TBA Val-25-to-Ile substitution in the envelope precursor polyprotein, gPr80env, is responsible for the temperature sensitivity, inefficient processing of gPr80env, and neurovirulence of ts1, a mutant of Moloney murine leukemia virus TB.Potential retroviral RNAs in Creutzfeldt-Jakob diseaseIdentification of point mutations in the envelope gene of Moloney murine leukemia virus TB temperature-sensitive paralytogenic mutant ts1: molecular determinants for neurovirulence.Correlation of specific virus-astrocyte interactions and cytopathic effects induced by ts1, a neurovirulent mutant of Moloney murine leukemia virus.Activation of transcription factor Nrf-2 and its downstream targets in response to moloney murine leukemia virus ts1-induced thiol depletion and oxidative stress in astrocytes.Evidence suggesting that PrP is not the infectious agent in Creutzfeldt-Jakob disease.
P2860
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P2860
Noninflammatory spongiform polioencephalomyelopathy caused by a neurotropic temperature-sensitive mutant of Moloney murine leukemia virus TB.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Noninflammatory spongiform pol ...... oney murine leukemia virus TB.
@ast
Noninflammatory spongiform pol ...... oney murine leukemia virus TB.
@en
type
label
Noninflammatory spongiform pol ...... oney murine leukemia virus TB.
@ast
Noninflammatory spongiform pol ...... oney murine leukemia virus TB.
@en
prefLabel
Noninflammatory spongiform pol ...... oney murine leukemia virus TB.
@ast
Noninflammatory spongiform pol ...... oney murine leukemia virus TB.
@en
P2093
P2860
P1476
Noninflammatory spongiform pol ...... oney murine leukemia virus TB.
@en
P2093
P2860
P304
P407
P577
1986-09-01T00:00:00Z