Domain swapping between FEN-1 and XPG defines regions in XPG that mediate nucleotide excision repair activity and substrate specificity. - Wikidata - wikimedia - TriplyDB

Domain swapping between FEN-1 and XPG defines regions in XPG that mediate nucleotide excision repair activity and substrate specificity.

Domain swapping between FEN-1 and XPG defines regions in XPG that mediate nucleotide excision repair activity and substrate specificity.

http://www.wikidata.org/entity/Q35837402

about

Nucleotide excision repair in eukaryotes Unpairing and gating: sequence-independent substrate recognition by FEN superfamily nucleases Human Flap Endonuclease Structures, DNA Double-Base Flipping, and a Unified Understanding of the FEN1 Superfamily Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family Structural and functional evidence that Rad4 competes with Rad2 for binding to the Tfb1 subunit of TFIIH in NER Structural and functional characterization of interactions involving the Tfb1 subunit of TFIIH and the NER factor Rad2 Significance of the dissociation of Dna2 by flap endonuclease 1 to Okazaki fragment processing in Saccharomyces cerevisiae.Dissociation of CAK from core TFIIH reveals a functional link between XP-G/CS and the TFIIH disassembly state.Dna2 is a structure-specific nuclease, with affinity for 5'-flap intermediates.Reconstitution of eukaryotic lagging strand DNA replication.Flap endonuclease 1 mechanism analysis indicates flap base binding prior to threading Initiation of DNA damage responses through XPG-related nucleases Structure and specificity of FEN-1 from Methanopyrus kandleri The DNA repair endonuclease XPG interacts directly and functionally with the WRN helicase defective in Werner syndrome The transcription-coupled repair protein ERCC6/CSB also protects against repeat expansion in a mouse model of the fragile X premutation.Association between ERCC5 gene polymorphisms and breast cancer risk Molecular mechanisms of xeroderma pigmentosum (XP) proteins.Hot topics in DNA repair: the molecular basis for different disease states caused by mutations in TFIIH and XPG.The wonders of flap endonucleases: structure, function, mechanism and regulation.Coordination of dual incision and repair synthesis in human nucleotide excision repair.Regulation of endonuclease activity in human nucleotide excision repair.Molecular mechanism of global genome nucleotide excision repair.Docking of a specialized PIP Box onto chromatin-bound PCNA creates a degron for the ubiquitin ligase CRL4Cdt2 DmGEN shows a flap endonuclease activity, cleaving the blocked-flap structure and model replication fork.Distinct Mechanisms of Nuclease-Directed DNA-Structure-Induced Genetic Instability in Cancer Genomes.

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P2860

Domain swapping between FEN-1 and XPG defines regions in XPG that mediate nucleotide excision repair activity and substrate specificity.

http://www.wikidata.org/entity/Q35837402

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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name

Domain swapping between FEN-1 ...... ity and substrate specificity.

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Domain swapping between FEN-1 ...... ity and substrate specificity.

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type

label

Domain swapping between FEN-1 ...... ity and substrate specificity.

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Domain swapping between FEN-1 ...... ity and substrate specificity.

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Domain swapping between FEN-1 ...... ity and substrate specificity.

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Domain swapping between FEN-1 ...... ity and substrate specificity.

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Nucleic Acids Research

P1476

Domain swapping between FEN-1 ...... vity and substrate specificity

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P2093

Fabrizio Thorel

http://www.w3.org/2001/XMLSchema#string

Isabelle Dunand-Sauthier

http://www.w3.org/2001/XMLSchema#string

Lidija Staresincic

http://www.w3.org/2001/XMLSchema#string

Marcel Hohl

http://www.w3.org/2001/XMLSchema#string

Orlando D Schärer

http://www.w3.org/2001/XMLSchema#string

Pascale Jaquier-Gubler

http://www.w3.org/2001/XMLSchema#string

Stuart G Clarkson

http://www.w3.org/2001/XMLSchema#string

P2860

Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity

Conserved residues of human XPG protein important for nuclease activity and function in nucleotide excision repair

Strong functional interactions of TFIIH with XPC and XPG in human DNA nucleotide excision repair, without a preassembled repairosome

Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne Syndrome

Structural determinants for substrate binding and catalysis by the structure-specific endonuclease XPG

RPA involvement in the damage-recognition and incision steps of nucleotide excision repair

Interactions involving the human RNA polymerase II transcription/nucleotide excision repair complex TFIIH, the nucleotide excision repair protein XPG, and Cockayne syndrome group B (CSB) protein

XPG endonuclease makes the 3' incision in human DNA nucleotide excision repair

Suppression of UV-induced apoptosis by the human DNA repair protein XPG

The characterization of a mammalian DNA structure-specific endonuclease

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3053-3063

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scholarly article

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10.1093/NAR/GKM092

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9

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35

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2007-04-22T00:00:00Z

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6377330

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17452369

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1888826

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