Long-lasting effects of a PEGylated mutant cocaine esterase (CocE) on the reinforcing and discriminative stimulus effects of cocaine in rats.
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Subunit Stabilization and Polyethylene Glycolation of Cocaine Esterase Improves In Vivo Residence TimeRational Design, Preparation, and Characterization of a Therapeutic Enzyme Mutant with Improved Stability and Function for Cocaine DetoxificationAccelerating cocaine metabolism as an approach to the treatment of cocaine abuse and toxicityCombined cocaine hydrolase gene transfer and anti-cocaine vaccine synergistically block cocaine-induced locomotion.Bacterial cocaine esterase: a protein-based therapy for cocaine overdose and addictionRepeated administration of a mutant cocaine esterase: effects on plasma cocaine levels, cocaine-induced cardiovascular activity, and immune responses in rhesus monkeys.Maintenance of reinforcement to address the chronic nature of drug addiction.Determinants of conditioned reinforcing effectiveness: Dopamine D2-like receptor agonist-stimulated responding for cocaine-associated stimuli.Differential Roles for Dopamine D1-Like and D2-Like Receptors in Mediating the Reinforcing Effects of Cocaine: Convergent Evidence from Pharmacological and Genetic Studies.Medications Discovery: Importance of Assessment of Drug Self Administration Dose-Effect Curves.Individual Differences in the Relative Reinforcing Effects of 3,4-Methylenedioxypyrovalerone under Fixed and Progressive Ratio Schedules of Reinforcement in Rats.Biologics to treat substance use disorders: Current status and new directionsThinking outside the synapse: pharmacokinetic-based medications for cocaine addiction.
P2860
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P2860
Long-lasting effects of a PEGylated mutant cocaine esterase (CocE) on the reinforcing and discriminative stimulus effects of cocaine in rats.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Long-lasting effects of a PEGy ...... us effects of cocaine in rats.
@ast
Long-lasting effects of a PEGy ...... us effects of cocaine in rats.
@en
type
label
Long-lasting effects of a PEGy ...... us effects of cocaine in rats.
@ast
Long-lasting effects of a PEGy ...... us effects of cocaine in rats.
@en
prefLabel
Long-lasting effects of a PEGy ...... us effects of cocaine in rats.
@ast
Long-lasting effects of a PEGy ...... us effects of cocaine in rats.
@en
P2093
P2860
P356
P1476
Long-lasting effects of a PEGy ...... us effects of cocaine in rats.
@en
P2093
Alyssa R Cunningham
Diwahar Narasimhan
Gregory T Collins
James H Woods
Joseph Nichols
Matthew E Zaks
Roger K Sunahara
P2860
P2888
P304
P356
10.1038/NPP.2011.226
P407
P50
P577
2011-10-12T00:00:00Z