The mechanism of V(D)J recombination: a balance of diversity, specificity, and stability.
about
Quantitative and qualitative changes in V-J alpha rearrangements during mouse thymocytes differentiation: implication for a limited T cell receptor alpha chain repertoireYeast artificial chromosome contigs reveal that distal variable-region genes reside at least 3 megabases from the joining regions in the murine immunoglobulin kappa locus.Activation of V(D)J recombination induces the formation of interlocus joints and hybrid joints in scid pre-B-cell lines.Identification of a chicken RAD52 homologue suggests conservation of the RAD52 recombination pathway throughout the evolution of higher eukaryotes.Double-strand break repair by interchromosomal recombination: an in vivo repair mechanism utilized by multiple somatic tissues in mammals.Ku80 is required for addition of N nucleotides to V(D)J recombination junctions by terminal deoxynucleotidyl transferaseSuppression of crossing-over by DNA methylation in Ascobolus.The long isoform of terminal deoxynucleotidyl transferase enters the nucleus and, rather than catalyzing nontemplated nucleotide addition, modulates the catalytic activity of the short isoform.Most alpha/beta T cell receptor diversity is due to terminal deoxynucleotidyl transferaseHigh-frequency illegitimate integration of transfected DNA at preintegrated target sites in a mammalian genomeMechanisms of overlap formation in nonhomologous DNA end joining.A DNA end-binding factor involved in double-strand break repair and V(D)J recombination.Illegitimate recombination induced by DNA double-strand breaks in a mammalian chromosome.Biased T-cell receptor delta element recombination in scid thymocytes.Modeling the dynamics of neonatal CD8+ T-cell responses.Genetic basis of neuronal individuality in the mammalian brain.Structure of nonhairpin coding-end DNA breaks in cells undergoing V(D)J recombination.XLF deficiency results in reduced N-nucleotide addition during V(D)J recombination.Regulation of DNA metabolic enzymes upon induction of preB cell development and V(D)J recombination: up-regulation of DNA polymerase delta.SCID mice and the study of parasitic disease.Increased frequency of aberrant V(D)J recombination products in core RAG-expressing mice.Nonhomologous DNA end joining in Schizosaccharomyces pombe efficiently eliminates DNA double-strand-breaks from haploid sequences.The role of mitotic recombination in carcinogenesis.Additional TCRV beta primers and minor method modifications improve detection of clonal T-cell populations by RT-PCR.The SCID mouse: relevance as an animal model system for studying human disease.Repertoires of antigen receptors in Tdt congenitally deficient mice.Stimulation of defective DNA transfer activity in recombination deficient SCID cell extracts by a 72-kDa protein from wild-type thymocytes.Somatic generation of hybrid antibody H chain genes in transgenic mice via interchromosomal gene conversion.V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair.Molecular codes for neuronal individuality and cell assembly in the brain.Stem cell origins of leukaemia and curabilityProgrammed DNA degradation and nucleolar biogenesis occur in distinct organelles during macronuclear development in Tetrahymena.
P2860
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P2860
The mechanism of V(D)J recombination: a balance of diversity, specificity, and stability.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
The mechanism of V(D)J recombination: a balance of diversity, specificity, and stability.
@ast
The mechanism of V(D)J recombination: a balance of diversity, specificity, and stability.
@en
type
label
The mechanism of V(D)J recombination: a balance of diversity, specificity, and stability.
@ast
The mechanism of V(D)J recombination: a balance of diversity, specificity, and stability.
@en
prefLabel
The mechanism of V(D)J recombination: a balance of diversity, specificity, and stability.
@ast
The mechanism of V(D)J recombination: a balance of diversity, specificity, and stability.
@en
P1433
P1476
The mechanism of V(D)J recombination: a balance of diversity, specificity, and stability.
@en
P2093
P304
P356
10.1016/0092-8674(92)90237-7
P407
P577
1992-09-01T00:00:00Z