Detection and intracellular localization of equine herpesvirus 1 IR1 and IR2 gene products by using monoclonal antibodies.
about
The EICP22 protein of equine herpesvirus 1 physically interacts with the immediate-early protein and with itself to form dimers and higher-order complexesThe unique IR2 protein of equine herpesvirus 1 negatively regulates viral gene expressionThe equine herpesvirus-1 (EHV-1) IR3 transcript downregulates expression of the IE gene and the absence of IR3 gene expression alters EHV-1 biological properties and virulence.Properties of an equine herpesvirus 1 mutant devoid of the internal inverted repeat sequence of the genomic short region.The early UL3 gene of equine herpesvirus-1 encodes a tegument protein not essential for replication or virulence in the mouseNuclear localization and transcriptional activation activities of truncated versions of the immediate-early gene product of equine herpesvirus 1Expression and function of the equine herpesvirus 1 virion-associated host shutoff homolog.The ICP22 protein of equine herpesvirus 1 cooperates with the IE protein to regulate viral gene expression.The equine herpesvirus-1 IR3 gene that lies antisense to the sole immediate-early (IE) gene is trans-activated by the IE protein, and is poorly expressed to a protein.Development of a bacterial artificial chromosome (BAC) recombineering procedure using galK-untranslated region (UTR) for the mutation of diploid genes.Identification of functional domains of the IR2 protein of equine herpesvirus 1 required for inhibition of viral gene expression and replication.Full trans-activation mediated by the immediate-early protein of equine herpesvirus 1 requires a consensus TATA box, but not its cognate binding sequence.The IR4 auxiliary regulatory protein expands the in vitro host range of equine herpesvirus 1 and is essential for pathogenesis in the murine model.
P2860
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P2860
Detection and intracellular localization of equine herpesvirus 1 IR1 and IR2 gene products by using monoclonal antibodies.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Detection and intracellular lo ...... y using monoclonal antibodies.
@ast
Detection and intracellular lo ...... y using monoclonal antibodies.
@en
type
label
Detection and intracellular lo ...... y using monoclonal antibodies.
@ast
Detection and intracellular lo ...... y using monoclonal antibodies.
@en
prefLabel
Detection and intracellular lo ...... y using monoclonal antibodies.
@ast
Detection and intracellular lo ...... y using monoclonal antibodies.
@en
P2093
P2860
P1433
P1476
Detection and intracellular lo ...... by using monoclonal antibodies
@en
P2093
D J O'Callaghan
G B Caughman
P2860
P304
P407
P577
1995-05-01T00:00:00Z