Ski represses bone morphogenic protein signaling in Xenopus and mammalian cells
about
The Ski-binding protein C184M negatively regulates tumor growth factor-beta signaling by sequestering the Smad proteins in the cytoplasmThe transforming activity of Ski and SnoN is dependent on their ability to repress the activity of Smad proteinsInteraction with Smad4 is indispensable for suppression of BMP signaling by c-SkiThe integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokinesIdentification of mZnf8, a mouse Krüppel-like transcriptional repressor, as a novel nuclear interaction partner of Smad1.Opposing functions of ZEB proteins in the regulation of the TGFbeta/BMP signaling pathwayOveractive bone morphogenetic protein signaling in heterotopic ossification and Duchenne muscular dystrophyDirect interaction of Ski with either Smad3 or Smad4 is necessary and sufficient for Ski-mediated repression of transforming growth factor-beta signalingTwo short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoNA direct intersection between p53 and transforming growth factor beta pathways targets chromatin modification and transcription repression of the alpha-fetoprotein geneCorl1, a novel neuronal lineage-specific transcriptional corepressor for the homeodomain transcription factor Lbx1SnoN suppresses maturation of chondrocytes by mediating signal cross-talk between transforming growth factor-β and bone morphogenetic protein pathways.fussel (fuss)--A negative regulator of BMP signaling in Drosophila melanogaster.Expression profiling of transforming growth factor beta superfamily genes in developing orofacial tissue.New intracellular components of bone morphogenetic protein/Smad signaling cascades.BMP-2 and TGF-β1 mediate biglycan-induced pro-osteogenic reprogramming in aortic valve interstitial cells.The adipocyte clock controls brown adipogenesis through the TGF-β and BMP signaling pathwaysSmad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate.Dynamic signaling for neural stem cell fate determination.Ski and SnoN, potent negative regulators of TGF-beta signaling.c-Ski in health and disease.Bone morphogenetic protein-4: a novel therapeutic target for pathological cardiac hypertrophy/heart failure.Inhibition of skiA and skiB gene expression ventralizes zebrafish embryos.The SKI proto-oncogene enhances the in vivo repopulation of hematopoietic stem cells and causes myeloproliferative disease.How a radial glial cell decides to become a multiciliated ependymal cell.Expression of Ski can act as a negative feedback mechanism on retinoic acid signaling.Induction of ectopic olfactory structures and bone morphogenetic protein inhibition by Rossy, a group XII secreted phospholipase A2.The Ski oncoprotein is upregulated and localized at the centrosomes and mitotic spindle during mitosis.Ski inhibits TGF-β/phospho-Smad3 signaling and accelerates hypertrophic differentiation in chondrocytesNoggin suppression enhances in vitro osteogenesis and accelerates in vivo bone formation.Transcription factors-Intricate players of the bone morphogenetic protein signaling pathway.SKI complexes with the Smad complex; suppressing BMP2 signallingBMP-7 improved proliferation and hematopoietic reconstitution potential of ex vivo expanded cord blood-derived CD34(+) cells.
P2860
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P2860
Ski represses bone morphogenic protein signaling in Xenopus and mammalian cells
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Ski represses bone morphogenic protein signaling in Xenopus and mammalian cells
@ast
Ski represses bone morphogenic protein signaling in Xenopus and mammalian cells
@en
type
label
Ski represses bone morphogenic protein signaling in Xenopus and mammalian cells
@ast
Ski represses bone morphogenic protein signaling in Xenopus and mammalian cells
@en
prefLabel
Ski represses bone morphogenic protein signaling in Xenopus and mammalian cells
@ast
Ski represses bone morphogenic protein signaling in Xenopus and mammalian cells
@en
P2093
P2860
P356
P1476
Ski represses bone morphogenic protein signaling in Xenopus and mammalian cells
@en
P2093
P2860
P304
14394-14399
P356
10.1073/PNAS.97.26.14394
P407
P577
2000-12-01T00:00:00Z