Altered human CYP3A4 activity caused by Antley-Bixler syndrome-related variants of NADPH-cytochrome P450 oxidoreductase measured in a robust in vitro system
about
Pharmacogenomics of human P450 oxidoreductaseInfluence of various polymorphic variants of cytochrome P450 oxidoreductase (POR) on drug metabolic activity of CYP3A4 and CYP2B6Role of protein-protein interactions in cytochrome P450-mediated drug metabolism and toxicityIdentification of six novel P450 oxidoreductase missense variants in Ashkenazi and Moroccan Jewish populations.Instability of the Human Cytochrome P450 Reductase A287P Variant Is the Major Contributor to Its Antley-Bixler Syndrome-like Phenotype.Cytochrome b5 plays a dual role in the reaction cycle of cytochrome P450 3A4 during oxidation of the anticancer drug ellipticine.Microfluidic Gut-liver chip for reproducing the first pass metabolism.
P2860
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P2860
Altered human CYP3A4 activity caused by Antley-Bixler syndrome-related variants of NADPH-cytochrome P450 oxidoreductase measured in a robust in vitro system
description
2012 nî lūn-bûn
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name
Altered human CYP3A4 activity ...... ed in a robust in vitro system
@ast
Altered human CYP3A4 activity ...... ed in a robust in vitro system
@en
type
label
Altered human CYP3A4 activity ...... ed in a robust in vitro system
@ast
Altered human CYP3A4 activity ...... ed in a robust in vitro system
@en
prefLabel
Altered human CYP3A4 activity ...... ed in a robust in vitro system
@ast
Altered human CYP3A4 activity ...... ed in a robust in vitro system
@en
P2093
P2860
P50
P356
P1476
Altered human CYP3A4 activity ...... ed in a robust in vitro system
@en
P2093
Bettie Sue Masters
Christopher C Marohnic
Daniela Moutinho
Satya P Panda
P2860
P304
P356
10.1124/DMD.111.042820
P577
2012-01-17T00:00:00Z