Recombinant CUB-1 domain polypeptide inhibits the cleavage of ULVWF strings by ADAMTS13 under flow conditions.
about
ADAMTS-12 associates with and degrades cartilage oligomeric matrix proteinPathophysiology of thrombotic thrombocytopenic purpuraPathogenesis of thrombotic microangiopathiesProteolytic processing of von Willebrand factor by adamts13 and leukocyte proteasesCUZD1 and anti-CUZD1 antibodies as markers of cancer and inflammatory bowel diseasesADAMTS13 and von Willebrand factor in thrombotic thrombocytopenic purpuraPlatelet glycoprotein Ibalpha forms catch bonds with human WT vWF but not with type 2B von Willebrand disease vWF.The interaction between factor H and Von Willebrand factor.Attack of the acronyms: TTP, VWF, ADAMTS-13 and SELDI-TOF-MS.Further characterization of ADAMTS-13 inactivation by thrombin.Insights into von Willebrand factor proteolysis: clinical implications.An IAP retrotransposon in the mouse ADAMTS13 gene creates ADAMTS13 variant proteins that are less effective in cleaving von Willebrand factor multimers.Correction of ADAMTS13 deficiency by in utero gene transfer of lentiviral vector encoding ADAMTS13 genes.Effects of naturally occurring mutations in CUB-1 domain on synthesis, stability, and activity of ADAMTS-13.The distal carboxyl-terminal domains of ADAMTS13 are required for regulation of in vivo thrombus formation.Thrombotic microangiopathies: multimers, metalloprotease, and beyond.A shear-based assay for assessing plasma ADAMTS13 activity and inhibitors in patients with thrombotic thrombocytopenic purpuraHumoral immune response to ADAMTS13 in acquired thrombotic thrombocytopenic purpura.A novel flow-based assay reveals discrepancies in ADAMTS-13 inhibitor assessment as compared with a conventional clinical static assay.ADAMTS-13 in the Diagnosis and Management of Thrombotic Microangiopathies.Conformational activation of ADAMTS13.ADAMTS13 and von Willebrand factor interactions.ADAMTS13 autoantibodies cloned from patients with acquired thrombotic thrombocytopenic purpura: 1. Structural and functional characterization in vitroForce-induced cleavage of single VWFA1A2A3 tridomains by ADAMTS-13.Disulfide bond reduction of von Willebrand factor by ADAMTS-13.A conformation-sensitive monoclonal antibody against the A2 domain of von Willebrand factor reduces its proteolysis by ADAMTS13Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor.Insights into how CUB domains can exert specific functions while sharing a common fold: conserved and specific features of the CUB1 domain contribute to the molecular basis of procollagen C-proteinase enhancer-1 activity.Full-length sequence of mouse acupuncture-induced 1-L (aig1l) gene including its transcriptional start site.Exosite interactions contribute to tension-induced cleavage of von Willebrand factor by the antithrombotic ADAMTS13 metalloproteaseThe cooperative activity between the carboxyl-terminal TSP1 repeats and the CUB domains of ADAMTS13 is crucial for recognition of von Willebrand factor under flow.A novel binding site for ADAMTS13 constitutively exposed on the surface of globular VWF.Structure-function and regulation of ADAMTS-13 protease.ADAMTS13 bound to endothelial cells exhibits enhanced cleavage of von Willebrand factor.Identification of the matriptase second CUB domain as the secondary site for interaction with hepatocyte growth factor activator inhibitor type-1.Sturgeon hatching enzyme and the mechanism of egg envelope digestion: Insight into changes in the mechanism of egg envelope digestion during the evolution of ray-finned fish.Cloning and sequence analysis of Bufo arenarum oviductin cDNA and detection of its orthologous gene expression in the mouse female reproductive tract.Removal of the C-Terminal Domains of ADAMTS13 by Activated Coagulation Factor XI induces Platelet Adhesion on Endothelial Cells under Flow Conditions.Human endothelial cells synthesize and release ADAMTS-13.Cysteine residues in CUB-1 domain are critical for ADAMTS13 secretion and stability.
P2860
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P2860
Recombinant CUB-1 domain polypeptide inhibits the cleavage of ULVWF strings by ADAMTS13 under flow conditions.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Recombinant CUB-1 domain polyp ...... DAMTS13 under flow conditions.
@ast
Recombinant CUB-1 domain polyp ...... DAMTS13 under flow conditions.
@en
type
label
Recombinant CUB-1 domain polyp ...... DAMTS13 under flow conditions.
@ast
Recombinant CUB-1 domain polyp ...... DAMTS13 under flow conditions.
@en
prefLabel
Recombinant CUB-1 domain polyp ...... DAMTS13 under flow conditions.
@ast
Recombinant CUB-1 domain polyp ...... DAMTS13 under flow conditions.
@en
P2093
P2860
P1433
P1476
Recombinant CUB-1 domain polyp ...... DAMTS13 under flow conditions.
@en
P2093
Jing-Fei Dong
Joel L Moake
José A López
Leticia Nolasco
Santiago Cal
Yuandong Peng
Zhenyin Tao
P2860
P304
P356
10.1182/BLOOD-2005-05-2029
P407
P577
2005-09-01T00:00:00Z