The FIP1L1-PDGFRA fusion gene cooperates with IL-5 to induce murine hypereosinophilic syndrome (HES)/chronic eosinophilic leukemia (CEL)-like disease.
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Siglec-F antibody administration to mice selectively reduces blood and tissue eosinophilsEosinophil survival and apoptosis in health and disease.What targeting eosinophils has taught us about their role in diseases.FIP1L1/PDGFR alpha-associated systemic mastocytosis.Identification of JAK2 as a mediator of FIP1L1-PDGFRA-induced eosinophil growth and function in CELMechanisms of eosinophilia in the pathogenesis of hypereosinophilic disordersCurrent concepts on the pathogenesis of the hypereosinophilic syndrome/chronic eosinophilic leukemia.Gastrointestinal eosinophiliaFibroblast growth factor receptor and platelet-derived growth factor receptor abnormalities in eosinophilic myeloproliferative disorders.Eosinophil viability is increased by acidic pH in a cAMP- and GPR65-dependent mannerBiology of the eosinophilRecent breakthroughs in the understanding and management of chronic eosinophilic leukemia.World Health Organization-defined eosinophilic disorders: 2011 update on diagnosis, risk stratification, and management.World Health Organization-defined eosinophilic disorders: 2012 update on diagnosis, risk stratification, and management.World Health Organization-defined eosinophilic disorders: 2014 update on diagnosis, risk stratification, and management.Mutations in tyrosine kinase and tyrosine phosphatase and their relevance to the target therapy in hematologic malignancies.ETV6-PDGFRB and FIP1L1-PDGFRA stimulate human hematopoietic progenitor cell proliferation and differentiation into eosinophils: the role of nuclear factor-κB.Lyn mediates FIP1L1-PDGFRA signal pathway facilitating IL-5RA intracellular signal through FIP1L1-PDGFRA/JAK2/Lyn/Akt network complex in CEL.F604S exchange in FIP1L1-PDGFRA enhances FIP1L1-PDGFRA protein stability via SHP-2 and SRC: a novel mode of kinase inhibitor resistance.FIP1L1-PDGFRalpha imposes eosinophil lineage commitment on hematopoietic stem/progenitor cells.The severity of FIP1L1-PDGFRA-positive chronic eosinophilic leukaemia is associated with polymorphic variation at the IL5RA locus.World Health Organization-defined eosinophilic disorders: 2017 update on diagnosis, risk stratification, and management.Concomitant FIP1L1-PDGFRA fusion gene and T-cell clonality in a case of chronic eosinophilic leukemia with clonal evolution and an incomplete response to imatinib.Transient macular erythema with eosinophilia in a patient carrying the FIP1L1-PDGFRA fusion gene.
P2860
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P2860
The FIP1L1-PDGFRA fusion gene cooperates with IL-5 to induce murine hypereosinophilic syndrome (HES)/chronic eosinophilic leukemia (CEL)-like disease.
description
2006 nî lūn-bûn
@nan
2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
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2006年论文
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name
The FIP1L1-PDGFRA fusion gene ...... c leukemia (CEL)-like disease.
@ast
The FIP1L1-PDGFRA fusion gene ...... c leukemia (CEL)-like disease.
@en
type
label
The FIP1L1-PDGFRA fusion gene ...... c leukemia (CEL)-like disease.
@ast
The FIP1L1-PDGFRA fusion gene ...... c leukemia (CEL)-like disease.
@en
prefLabel
The FIP1L1-PDGFRA fusion gene ...... c leukemia (CEL)-like disease.
@ast
The FIP1L1-PDGFRA fusion gene ...... c leukemia (CEL)-like disease.
@en
P2093
P2860
P1433
P1476
The FIP1L1-PDGFRA fusion gene ...... c leukemia (CEL)-like disease.
@en
P2093
Andrew W Lee
David A Williams
Eric B Brandt
Hiroko Saito Akei
Jose A Cancelas
Marc E Rothenberg
Yoshiyuki Yamada
P2860
P304
P356
10.1182/BLOOD-2005-08-3153
P407
P577
2006-01-17T00:00:00Z