Continuous in vivo infusion of interferon-gamma (IFN-gamma) enhances engraftment of syngeneic wild-type cells in Fanca-/- and Fancg-/- mice - Wikidata - wikimedia - TriplyDB

Continuous in vivo infusion of interferon-gamma (IFN-gamma) enhances engraftment of syngeneic wild-type cells in Fanca-/- and Fancg-/- mice

Continuous in vivo infusion of interferon-gamma (IFN-gamma) enhances engraftment of syngeneic wild-type cells in Fanca-/- and Fancg-/- mice

http://www.wikidata.org/entity/Q35848750

about

Fanconi anemia and the cell cycle: new perspectives on aneuploidy Mouse models of Fanconi anemia An abnormal bone marrow microenvironment contributes to hematopoietic dysfunction in Fanconi anemia.p38 MAPK inhibition suppresses the TLR-hypersensitive phenotype in FANCC- and FANCA-deficient mononuclear phagocytes Bone marrow cell transcripts from Fanconi anaemia patients reveal in vivo alterations in mitochondrial, redox and DNA repair pathways.Stem cell gene therapy for fanconi anemia: report from the 1st international Fanconi anemia gene therapy working group meeting.Disrupted Signaling through the Fanconi Anemia Pathway Leads to Dysfunctional Hematopoietic Stem Cell Biology: Underlying Mechanisms and Potential Therapeutic Strategies.TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells.Defective homing is associated with altered Cdc42 activity in cells from patients with Fanconi anemia group A.Overnight transduction with foamyviral vectors restores the long-term repopulating activity of Fancc-/- stem cells.TNF-α, a good or bad factor in hematological diseases?Interleukin 8/KC enhances G-CSF induced hematopoietic stem/progenitor cell mobilization in Fancg deficient mice.The PI3K/Akt1 pathway enhances steady-state levels of FANCL.Oxidative stress in Fanconi anemia hematopoiesis and disease progression.Mesenchymal stem/progenitor cells promote the reconstitution of exogenous hematopoietic stem cells in Fancg-/- mice in vivo.TNF-α signaling in Fanconi anemia.The role of stat1b in zebrafish hematopoiesis.Inflammatory ROS promote and cooperate with the Fanconi anemia mutation for hematopoietic senescence.AMD3100 synergizes with G-CSF to mobilize repopulating stem cells in Fanconi anemia knockout mice.TGF-β: a master regulator of the bone marrow failure puzzle in Fanconi anemia.Inflammatory reactive oxygen species-mediated hemopoietic suppression in Fancc-deficient mice Loss of the homologous recombination gene rad51 leads to Fanconi anemia-like symptoms in zebrafish.

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P2860

Continuous in vivo infusion of interferon-gamma (IFN-gamma) enhances engraftment of syngeneic wild-type cells in Fanca-/- and Fancg-/- mice

http://www.wikidata.org/entity/Q35848750

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P2860

FANCC interacts with Hsp70 to protect hematopoietic cells from IFN-gamma/TNF-alpha-mediated cytotoxicity.

A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M

A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome

Mice with a targeted disruption of the Fanconi anemia homolog Fanca

Engraftment of hematopoietic progenitor cells transduced with the Fanconi anemia group C gene (FANCC)

The emerging genetic and molecular basis of Fanconi anaemia

Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9

Homing and engraftment potential of Sca-1(+)lin(-) cells fractionated on the basis of adhesion molecule expression and position in cell cycle.

Second-generation interferons for cancer: clinical targets.

Immunomodulatory approaches to augment phagocyte-mediated host defense for treatment of infectious diseases.

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