High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities. - Wikidata - wikimedia - TriplyDB

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.

http://www.wikidata.org/entity/Q35858015

about

Ptk7 and Mcc, Unfancied Components in Non-Canonical Wnt Signaling and Cancer Mapping paths: new approaches to dissect eukaryotic signaling circuitry TRAPP Complexes in Secretion and Autophagy Adaptive preconditioning in neurological diseases – therapeutic insights from proteostatic perturbations CRISPR-Cas9: from Genome Editing to Cancer Research CRISPR guide RNA design for research applications Accelerating glioblastoma drug discovery: Convergence of patient-derived models, genome editing and phenotypic screening Pooled-matrix protein interaction screens using Barcode Fusion Genetics Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening The BioGRID interaction database: 2017 update OGEE v2: an update of the online gene essentiality database with special focus on differentially essential genes in human cancer cell lines A CRISPR toolbox to study virus-host interactions Genomic variants reveal differential evolutionary constraints on human transglutaminases and point towards unrecognized significance of transglutaminase 2.A novel RNA sequencing data analysis method for cell line authentication.CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells.Synthetic lethality: emerging targets and opportunities in melanoma.Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens Serotonergic system antagonists target breast tumor initiating cells and synergize with chemotherapy to shrink human breast tumor xenografts.CRISPR/Cas9: From Genome Engineering to Cancer Drug Discovery Flexible CRISPR library construction using parallel oligonucleotide retrieval.A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors.Systematic comparison of CRISPR/Cas9 and RNAi screens for essential genes.Induced Pluripotent Stem Cells Meet Genome Editing Applications of CRISPR technologies in research and beyond.A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia.BAGEL: a computational framework for identifying essential genes from pooled library screens.Cas-Database: web-based genome-wide guide RNA library design for gene knockout screens using CRISPR-Cas9.Genome-scale CRISPR pooled screens.Practical Considerations for Using Pooled Lentiviral CRISPR Libraries.Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR.Increasing the performance of pooled CRISPR-Cas9 drop-out screening.Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation.Somatic Mutation Patterns in Hemizygous Genomic Regions Unveil Purifying Selection during Tumor Evolution Validation of Synthetic CRISPR Reagents as a Tool for Arrayed Functional Genomic Screening.sgRNA Scorer 2.0: A Species-Independent Model To Predict CRISPR/Cas9 Activity.Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells.Scalable Design of Paired CRISPR Guide RNAs for Genomic Deletion Tissue-specific tumorigenesis: context matters.Functional interrogation of non-coding DNA through CRISPR genome editing.

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High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.

http://www.wikidata.org/entity/Q35858015

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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name

High-Resolution CRISPR Screens ...... e-Specific Cancer Liabilities.

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High-Resolution CRISPR Screens ...... e-Specific Cancer Liabilities.

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type

label

High-Resolution CRISPR Screens ...... e-Specific Cancer Liabilities.

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High-Resolution CRISPR Screens ...... e-Specific Cancer Liabilities.

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High-Resolution CRISPR Screens ...... e-Specific Cancer Liabilities.

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High-Resolution CRISPR Screens ...... e-Specific Cancer Liabilities.

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J.CELL.2015.11.015

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High-Resolution CRISPR Screens ...... pe-Specific Cancer Liabilities

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Daniel Durocher

http://www.w3.org/2001/XMLSchema#string

Graham MacLeod

http://www.w3.org/2001/XMLSchema#string

Kevin R Brown

http://www.w3.org/2001/XMLSchema#string

Megha Chandrashekhar

http://www.w3.org/2001/XMLSchema#string

Michal Zimmermann

http://www.w3.org/2001/XMLSchema#string

Monika Mis

http://www.w3.org/2001/XMLSchema#string

Olivia S Rissland

http://www.w3.org/2001/XMLSchema#string

Patricia Mero

http://www.w3.org/2001/XMLSchema#string

Peter Dirks

http://www.w3.org/2001/XMLSchema#string

Sachdev Sidhu

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1515-1526

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scholarly article

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10.1016/J.CELL.2015.11.015

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6

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163

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Frederick P. Roth

Amélie Fradet-Turcotte

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Michael Aregger

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2015-11-25T00:00:00Z

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26627737

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