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Pim-2 phosphorylation of p21(Cip1/WAF1) enhances its stability and inhibits cell proliferation in HCT116 cellsMice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factorsPIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancersMolecular basis of inherited microcytic anemia due to defects in iron acquisition or heme synthesisPAP-1, a novel target protein of phosphorylation by pim-1 kinaseIdentification of heterochromatin protein 1 (HP1) as a phosphorylation target by Pim-1 kinase and the effect of phosphorylation on the transcriptional repression function of HP1(1)Pim-1 translocates sorting nexin 6/TRAF4-associated factor 2 from cytoplasm to nucleusThe PIM kinases in hematological cancersPim kinase inhibitors: a survey of the patent literaturePim1 inhibition as a novel therapeutic strategy for Alzheimer's diseaseThe oncogenic serine/threonine kinase Pim-1 phosphorylates and inhibits the activity of Cdc25C-associated kinase 1 (C-TAK1): a novel role for Pim-1 at the G2/M cell cycle checkpointEvidence that the Pim1 kinase gene is a direct target of HOXA9Pim1 serine/threonine kinase regulates the number and functions of murine hematopoietic stem cellsGenetic Modeling of PIM Proteins in Cancer: Proviral Tagging and Cooperation with Oncogenes, Tumor Suppressor Genes, and Carcinogens.Reassessing the role of C-MYB in tumorigenesis.In vitro evaluation of dihydropyridine-3-carbonitriles as potential cytotoxic agents through PIM-1 protein kinase inhibition.Activation of cell cycle arrest and apoptosis by the proto-oncogene Pim-2.Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.Regulation of C. elegans presynaptic differentiation and neurite branching via a novel signaling pathway initiated by SAM-10.Use of genetically engineered mice in drug discovery and development: wielding Occam's razor to prune the product portfolio.Testing electromagnetic fields for potential carcinogenic activity: a critical review of animal modelsPim1 kinase is upregulated in glioblastoma multiforme and mediates tumor cell survival.Frontier of epilepsy research - mTOR signaling pathway.Pim1 kinase is required to maintain tumorigenicity in MYC-expressing prostate cancer cells.A Novel Cinnamon-Related Natural Product with Pim-1 Inhibitory Activity Inhibits Leukemia and Skin CancerPIM1 gene cooperates with human BCL6 gene to promote the development of lymphomasDevelopmental stage-specific effects of Pim-1 dysregulation on murine bone marrow B cell development.EPO receptor circuits for primary erythroblast survivalAbnormal hematopoietic phenotypes in Pim kinase triple knockout mice.Double-strand break repair by homologous recombination in primary mouse somatic cells requires BRCA1 but not the ATM kinaseIdentification of quinones as novel PIM1 kinase inhibitorsProviral tagging in E mu-myc transgenic mice lacking the Pim-1 proto-oncogene leads to compensatory activation of Pim-2.Why target PIM1 for cancer diagnosis and treatment?Insights from Pim1 structure for anti-cancer drug design.Pre-clinical evidence of PIM kinase inhibitor activity in BCR-ABL1 unmutated and mutated Philadelphia chromosome-positive (Ph+) leukemias.PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer.PIM1: a promising target in patients with triple-negative breast cancer.PIM1 kinase is destabilized by ribosomal stress causing inhibition of cell cycle progression.Investigation of the intracellular stability and formation of a triple helix formed with a short purine oligonucleotide targeted to the murine c-pim-1 proto-oncogene promotor.Pim-1: A new biomarker in pulmonary arterial hypertension.
P2860
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P2860
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
In vivo analysis of Pim-1 deficiency
@ast
In vivo analysis of Pim-1 deficiency
@en
type
label
In vivo analysis of Pim-1 deficiency
@ast
In vivo analysis of Pim-1 deficiency
@en
prefLabel
In vivo analysis of Pim-1 deficiency
@ast
In vivo analysis of Pim-1 deficiency
@en
P2093
P2860
P356
P1476
In vivo analysis of Pim-1 deficiency
@en
P2093
van der Lugt NM
P2860
P304
P356
10.1093/NAR/21.20.4750
P407
P577
1993-10-01T00:00:00Z