Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease - Wikidata - wikimedia - TriplyDB

Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease

Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease

http://www.wikidata.org/entity/Q28277112

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The FOXP2-Driven Network in Developmental Disorders and Neurodegeneration Central insulin dysregulation and energy dyshomeostasis in two mouse models of Alzheimer's disease.Of Mice and Men: Comparative Analysis of Neuro-Inflammatory Mechanisms in Human and Mouse Using Cause-and-Effect Models.Necroptosis activation in Alzheimer's disease.Genetic reduction of Nrf2 exacerbates cognitive deficits in a mouse model of Alzheimer's disease.Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes.Acute tau knockdown in the hippocampus of adult mice causes learning and memory deficits.

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P2860

Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease

http://www.wikidata.org/entity/Q28277112

description

2016 nî lūn-bûn

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2016 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2016 թվականի հուլիսին հրատարակված գիտական հոդված

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2016年の論文

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2016年論文

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2016年論文

@zh-hant

2016年論文

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2016年論文

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2016年論文

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2016年论文

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name

Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease

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Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease

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Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease

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type

label

Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease

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Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease

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Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease

@nl

prefLabel

Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease

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Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease

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Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease

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S13024-016-0118-Z

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Molecular Neurodegeneration

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Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease

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Antonella Caccamo

http://www.w3.org/2001/XMLSchema#string

Darren M Shaw

http://www.w3.org/2001/XMLSchema#string

Ramon Velazquez

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P2860

Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease

Alzheimer's Disease

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase

The pim-1 oncogene encodes two related protein-serine/threonine kinases by alternative initiation at AUG and CUG

The human protooncogene product p33pim is expressed during fetal hematopoiesis and in diverse leukemias

Naturally secreted amyloid-beta increases mammalian target of rapamycin (mTOR) activity via a PRAS40-mediated mechanism

mTOR is a key modulator of ageing and age-related disease

Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments.

Methylene blue reduces aβ levels and rescues early cognitive deficit by increasing proteasome activity

Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's disease

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10.1186/S13024-016-0118-Z

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27412291

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Alzheimer's disease

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