Haploinsufficiency of yeast FEN1 causes instability of expanded CAG/CTG tracts in a length-dependent manner.
about
Evidence for a role of FEN1 in maintaining mitochondrial DNA integrityStoichiometry of base excision repair proteins correlates with increased somatic CAG instability in striatum over cerebellum in Huntington's disease transgenic miceComplementary roles for exonuclease 1 and Flap endonuclease 1 in maintenance of triplet repeatsPotassium bromate, a potent DNA oxidizing agent, exacerbates germline repeat expansion in a fragile X premutation mouse modelDefining genetic factors that modulate intergenerational CAG repeat instability in Drosophila melanogasterFunctional regulation of FEN1 nuclease and its link to cancerA 5', 8-cyclo-2'-deoxypurine lesion induces trinucleotide repeat deletion via a unique lesion bypass by DNA polymerase βRepeat instability during DNA repair: Insights from model systemsInstability of (CTG)n•(CAG)n trinucleotide repeats and DNA synthesisDNA base excision repair: a mechanism of trinucleotide repeat expansion.Altered replication in human cells promotes DMPK (CTG)(n) · (CAG)(n) repeat instabilitySmall molecule inhibitors uncover synthetic genetic interactions of human flap endonuclease 1 (FEN1) with DNA damage response genes.ATR protects the genome against CGG.CCG-repeat expansion in Fragile X premutation mice.Trinucleotide repeat deletion via a unique hairpin bypass by DNA polymerase β and alternate flap cleavage by flap endonuclease 1.CTG/CAG repeat instability is modulated by the levels of human DNA ligase I and its interaction with proliferating cell nuclear antigen: a distinction between replication and slipped-DNA repairAbnormal base excision repair at trinucleotide repeats associated with diseases: a tissue-selective mechanism.Expression levels of DNA replication and repair genes predict regional somatic repeat instability in the brain but are not altered by polyglutamine disease protein expression or age.Base excision repair of oxidative DNA damage coupled with removal of a CAG repeat hairpin attenuates trinucleotide repeat expansion.Dna2 on the road to Okazaki fragment processing and genome stability in eukaryotes.Expansion of CAG repeats in Escherichia coli is controlled by single-strand DNA exonucleases of both polarities.Replication-dependent instability at (CTG) x (CAG) repeat hairpins in human cells.SUMO-1 modification of FEN1 facilitates its interaction with Rad9-Rad1-Hus1 to counteract DNA replication stress
P2860
Q27939094-29436B83-BF74-413B-B029-953004C93745Q30972892-3BAF84E0-B1E8-4B87-B7A7-772B75ED8B97Q34121171-8863186F-EC0E-4444-85F0-72DCA9731855Q34182956-848FD1C0-872C-40C4-8DC3-56928E0C7170Q34477635-BD1F69D8-F500-4ACA-96E9-E127EA67990FQ34559690-2AFD7F7D-2D90-467F-A6D9-2F329D0E5696Q34712058-B22D5CF7-BF61-4CBD-9D8D-DC8BBE1534E5Q35680075-433609B5-85E9-4091-A9A4-811DECBE8DEBQ35847997-78EA2752-45B2-417A-A428-61D1BAEAD4DBQ35881868-2EB20178-B4AA-4CB9-BA48-361169C51927Q35943348-8B34EEA2-3A6D-4B1E-8764-02EB8EDB95A8Q36409202-FBA2A50E-A77C-4E83-B229-E36B28A7038CQ36457201-25EA32A8-99DB-4DC3-8ABB-DCF36A7BDF5EQ36580985-26EFCE78-C6A4-40F5-A283-A8D1C6DB7C7EQ37446749-49F90A31-031A-4CD1-8820-1674D7E62F5BQ37584997-111293A8-0A31-4199-B365-97EDD7C49503Q37593054-F9A6FB29-B317-4357-9C11-ECC1A9F784E5Q37680431-043000AF-8201-47A0-B902-4C54DB27E3B3Q37687363-71190C69-C671-4189-BBF4-1E062A08629AQ42086935-49469F38-9120-4945-9479-D1FB99B3ACC7Q42177075-151D3A69-BDD6-4722-9989-5F8D5C946589Q59132715-B54F7647-DA12-4420-B555-9DF3A23B1FEA
P2860
Haploinsufficiency of yeast FEN1 causes instability of expanded CAG/CTG tracts in a length-dependent manner.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Haploinsufficiency of yeast FE ...... in a length-dependent manner.
@ast
Haploinsufficiency of yeast FE ...... in a length-dependent manner.
@en
type
label
Haploinsufficiency of yeast FE ...... in a length-dependent manner.
@ast
Haploinsufficiency of yeast FE ...... in a length-dependent manner.
@en
prefLabel
Haploinsufficiency of yeast FE ...... in a length-dependent manner.
@ast
Haploinsufficiency of yeast FE ...... in a length-dependent manner.
@en
P2860
P1433
P1476
Haploinsufficiency of yeast FE ...... in a length-dependent manner.
@en
P2093
Catherine H Freudenreich
Jiahui Yang
P2860
P304
P356
10.1016/J.GENE.2007.01.025
P407
P577
2007-02-12T00:00:00Z