Woodchuck hepatitis virus X protein is present in chronically infected woodchuck liver and woodchuck hepatocellular carcinomas which are permissive for viral replication.
about
Cloning and characterization of a novel hepatitis B virus x binding protein that inhibits viral replication.The enigmatic X gene of hepatitis B virusHBV induced HCC: major risk factors from genetic to molecular levelHepatitis B virus HBx protein sensitizes cells to apoptotic killing by tumor necrosis factor alphaHepatitis B virus X protein colocalizes to mitochondria with a human voltage-dependent anion channel, HVDAC3, and alters its transmembrane potentialHepatitis B virus X protein impairs hepatic insulin signaling through degradation of IRS1 and induction of SOCS3.Involvement of DNA damage response pathways in hepatocellular carcinoma.Inhibitory effect of 2'-fluoro-5-methyl-beta-L-arabinofuranosyl-uracil on duck hepatitis B virus replication.Hepatitis B virus X protein stimulates viral genome replication via a DDB1-dependent pathway distinct from that leading to cell death.Regulation of RNA polymerase I-dependent promoters by the hepatitis B virus X protein via activated Ras and TATA-binding proteinHepatitis B virus X protein interferes with cellular DNA repair.Duck hepatitis B virus expresses a regulatory HBx-like protein from a hidden open reading frameRole of NF-kappaB and myc proteins in apoptosis induced by hepatitis B virus HBx protein.Sustained activation of mitogen-activated protein kinases and activator protein 1 by the hepatitis B virus X protein in mouse hepatocytes in vivo.Hepatitis B virus biology.Altered DNA mutation spectrum in aflatoxin b1-treated transgenic mice that express the hepatitis B virus x proteinImmune-induced evolutionary selection focused on a single reading frame in overlapping hepatitis B virus proteins.Hepatitis B virus x protein induces perinuclear mitochondrial clustering in microtubule- and Dynein-dependent manners.Liver repopulation with xenogenic hepatocytes in B and T cell-deficient mice leads to chronic hepadnavirus infection and clonal growth of hepatocellular carcinomaHepatitis B virus X antigen in the pathogenesis of chronic infections and the development of hepatocellular carcinoma.Activation of Src family kinases by hepatitis B virus HBx protein and coupled signaling to RasHepatitis B Virus X and Regulation of Viral Gene Expression.The mitogenic function of hepatitis B virus X protein resides within amino acids 51 to 140 and is modulated by N- and C-terminal regulatory regions.Antisense downregulation of N-myc1 in woodchuck hepatoma cells reverses the malignant phenotype.Metabolic labeling of woodchuck hepatitis B virus X protein in naturally infected hepatocytes reveals a bimodal half-life and association with the nuclear framework.The hepatitis B virus X protein transactivates viral core gene expression in vivo.Hepatitis B virus X protein acts as a tumor promoter in development of diethylnitrosamine-induced preneoplastic lesions.Hepatitis B virus HBx protein localizes to mitochondria in primary rat hepatocytes and modulates mitochondrial membrane potential.Hepatitis B virus X protein increases the Cdt1-to-geminin ratio inducing DNA re-replication and polyploidy.Differential effects on apoptosis induction in hepatocyte lines by stable expression of hepatitis B virus X protein.Farnesoid X receptor ablation sensitizes mice to hepatitis b virus X protein-induced hepatocarcinogenesis.Sustained activation of p38 mitogen-activated protein kinase and c-Jun N-terminal kinase pathways by hepatitis B virus X protein mediates apoptosis via induction of Fas/FasL and tumor necrosis factor (TNF) receptor 1/TNF-alpha expressionHepatitis B virus HBx protein activation of cyclin A-cyclin-dependent kinase 2 complexes and G1 transit via a Src kinase pathway.Role of HBx in hepatitis B virus persistence and its therapeutic implications.
P2860
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P2860
Woodchuck hepatitis virus X protein is present in chronically infected woodchuck liver and woodchuck hepatocellular carcinomas which are permissive for viral replication.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Woodchuck hepatitis virus X pr ...... missive for viral replication.
@ast
Woodchuck hepatitis virus X pr ...... missive for viral replication.
@en
type
label
Woodchuck hepatitis virus X pr ...... missive for viral replication.
@ast
Woodchuck hepatitis virus X pr ...... missive for viral replication.
@en
prefLabel
Woodchuck hepatitis virus X pr ...... missive for viral replication.
@ast
Woodchuck hepatitis virus X pr ...... missive for viral replication.
@en
P2093
P2860
P1433
P1476
Woodchuck hepatitis virus X pr ...... missive for viral replication.
@en
P2093
C E Rogler
P Schirmacher
P2860
P304
P407
P577
1996-08-01T00:00:00Z