Hepatitis B virus HBx protein activation of cyclin A-cyclin-dependent kinase 2 complexes and G1 transit via a Src kinase pathway.
about
Identification and characterization of avihepadnaviruses isolated from exotic anseriformes maintained in captivityThe enigmatic X gene of hepatitis B virusHepatitis B virus replication is associated with an HBx-dependent mitochondrion-regulated increase in cytosolic calcium levelsGenetic variation of hepatitis B virus and its significance for pathogenesisHepatitis B virus X protein induces apoptosis and cell cycle deregulation through interfering with DNA repair and checkpoint responses.Evaluation of transcriptional efficiency of hepatitis B virus covalently closed circular DNA by reverse transcription-PCR combined with the restriction enzyme digestion methodNatural variants of hepatitis B virus X protein have differential effects on the expression of cyclin-dependent kinase inhibitor p21 gene.Molecular Pathogenesis of Hepatitis-B-virus-associated Hepatocellular Carcinoma.Tumor suppressor micro RNA miR-145 and onco micro RNAs miR-21 and miR-222 expressions are differentially modulated by hepatitis B virus X protein in malignant hepatocytesThe effect of miR-338-3p on HBx deletion-mutant (HBx-d382) mediated liver-cell proliferation through CyclinD1 regulationHepatitis B and C virus hepatocarcinogenesis: lessons learned and future challenges.Tumor necrosis factor alpha inhibition of hepatitis B virus replication involves disruption of capsid Integrity through activation of NF-kappaB.Hepatocellular carcinoma: role of hepatitis B and hepatitis C viruses proteins in hepatocarcinogenesis.Tumor necrosis factor activates a conserved innate antiviral response to hepatitis B virus that destabilizes nucleocapsids and reduces nuclear viral DNA.Aggregate formation of hepatitis B virus X protein affects cell cycle and apoptosis.miR-338-3p is down-regulated by hepatitis B virus X and inhibits cell proliferation by targeting the 3'-UTR region of CyclinD1Cyclin-dependent kinase 2 phosphorylates s/t-p sites in the hepadnavirus core protein C-terminal domain and is incorporated into viral capsids.The molecular diagnosis of hepatitis B virus-associated hepatocellular carcinoma.Chronic hepatitis B in hepatocarcinogenesisTranscriptome-Wide Analysis of Hepatitis B Virus-Mediated Changes to Normal Hepatocyte Gene Expression.Hepatocyte Factor JMJD5 Regulates Hepatitis B Virus Replication through Interaction with HBxHepatitis B Virus-Encoded X Protein Downregulates EGFR Expression via Inducing MicroRNA-7 in Hepatocellular Carcinoma CellsHepatitis B virus X protein mediated suppression of miRNA-122 expression enhances hepatoblastoma cell proliferation through cyclin G1-p53 axisThe molecular and pathophysiological implications of hepatitis B X antigen in chronic hepatitis B virus infection.The direct and indirect roles of HBV in liver cancer: prospective markers for HCC screening and potential therapeutic targets.HBx-dependent cell cycle deregulation involves interaction with cyclin E/A-cdk2 complex and destabilization of p27Kip1.Hepatitis B virus X protein activates a survival signaling by linking SRC to phosphatidylinositol 3-kinase.Liver cell transformation in chronic HBV infection.The mitogenic function of hepatitis B virus X protein resides within amino acids 51 to 140 and is modulated by N- and C-terminal regulatory regions.c-ETS1 facilitates G1/S-phase transition by up-regulating cyclin E and CDK2 genes and cooperates with hepatitis B virus X protein for their deregulationThe C-terminal region of the hepatitis B virus X protein is essential for its stability and function.The hepatitis B virus HBx protein modulates cell cycle regulatory proteins in cultured primary human hepatocytes.Hepatitis B virus X protein activates the p38 mitogen-activated protein kinase pathway in dedifferentiated hepatocytesActivation of focal adhesion kinase by hepatitis B virus HBx protein: multiple functions in viral replication.Hepatitis B virus X protein differentially regulates cell cycle progression in X-transforming versus nontransforming hepatocyte (AML12) cell lines.Reconstitution of gene expression from a regulatory-protein-deficient hepatitis B virus genome by cell-permeable HBx protein.Hepatitis B virus regulatory HBx protein binding to DDB1 is required but is not sufficient for maximal HBV replicationCyclin E and cyclin A are likely targets of Src for PDGF-induced DNA synthesis in fibroblasts.The hepatitis B virus X protein modulates hepatocyte proliferation pathways to stimulate viral replication.The hepatitis B virus X protein functionally interacts with CREB-binding protein/p300 in the regulation of CREB-mediated transcription.
P2860
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P2860
Hepatitis B virus HBx protein activation of cyclin A-cyclin-dependent kinase 2 complexes and G1 transit via a Src kinase pathway.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Hepatitis B virus HBx protein ...... nsit via a Src kinase pathway.
@en
type
label
Hepatitis B virus HBx protein ...... nsit via a Src kinase pathway.
@en
prefLabel
Hepatitis B virus HBx protein ...... nsit via a Src kinase pathway.
@en
P2093
P2860
P1433
P1476
Hepatitis B virus HBx protein ...... nsit via a Src kinase pathway.
@en
P2093
M Bouchard
R J Schneider
S Giannakopoulos
P2860
P304
P356
10.1128/JVI.75.9.4247-4257.2001
P407
P577
2001-05-01T00:00:00Z