Endogenous reverse transcription assays reveal high-level resistance to the triphosphate of (-)2'-dideoxy-3'-thiacytidine by mutated M184V human immunodeficiency virus type 1
about
Inhibitors of human immunodeficiency virus type 1 reverse transcriptase target distinct phases of early reverse transcriptionDevelopment of a new cartridge radioimmunoassay for determination of intracellular levels of lamivudine triphosphate in the peripheral blood mononuclear cells of human immunodeficiency virus-infected patientsDecreased processivity of human immunodeficiency virus type 1 reverse transcriptase (RT) containing didanosine-selected mutation Leu74Val: a comparative analysis of RT variants Leu74Val and lamivudine-selected Met184Val.Efficacy of antiretroviral agents against murine replication-competent retrovirus infection in human cells.A cell-based strategy to assess intrinsic inhibition efficiencies of HIV-1 reverse transcriptase inhibitors.The role of unintegrated DNA in HIV infectionCompensation by the E138K mutation in HIV-1 reverse transcriptase for deficits in viral replication capacity and enzyme processivity associated with the M184I/V mutations.Molecular impact of the M184V mutation in human immunodeficiency virus type 1 reverse transcriptase.HIV-1 antiretroviral drug therapy.Human immunodeficiency virus type 1 nucleocapsid protein promotes efficient strand transfer and specific viral DNA synthesis by inhibiting TAR-dependent self-priming from minus-strand strong-stop DNA.The importance of the A-rich loop in human immunodeficiency virus type 1 reverse transcription and infectivity.Characterization of HIV-1 Resistance to Tenofovir Alafenamide In Vitro.Molecular mechanisms of tenofovir resistance conferred by human immunodeficiency virus type 1 reverse transcriptase containing a diserine insertion after residue 69 and multiple thymidine analog-associated mutations.The M184V mutation in the reverse transcriptase of human immunodeficiency virus type 1 impairs rescue of chain-terminated DNA synthesis.Molecular mechanisms of resistance to human immunodeficiency virus type 1 with reverse transcriptase mutations K65R and K65R+M184V and their effects on enzyme function and viral replication capacity.Lamivudine can exert a modest antiviral effect against human immunodeficiency virus type 1 containing the M184V mutation.Diminished RNA primer usage associated with the L74V and M184V mutations in the reverse transcriptase of human immunodeficiency virus type 1 provides a possible mechanism for diminished viral replication capacity.Structural Aspects of Drug Resistance and Inhibition of HIV-1 Reverse Transcriptase.Human immunodeficiency virus type 1: resistance to nucleoside analogues and replicative capacity in primary human macrophages.Differential maintenance of the M184V substitution in the reverse transcriptase of human immunodeficiency virus type 1 by various nucleoside antiretroviral agents in tissue culture.Proteomic profiling of HIV-infected T-cells by SWATH mass spectrometry.
P2860
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P2860
Endogenous reverse transcription assays reveal high-level resistance to the triphosphate of (-)2'-dideoxy-3'-thiacytidine by mutated M184V human immunodeficiency virus type 1
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Endogenous reverse transcripti ...... immunodeficiency virus type 1
@ast
Endogenous reverse transcripti ...... immunodeficiency virus type 1
@en
type
label
Endogenous reverse transcripti ...... immunodeficiency virus type 1
@ast
Endogenous reverse transcripti ...... immunodeficiency virus type 1
@en
prefLabel
Endogenous reverse transcripti ...... immunodeficiency virus type 1
@ast
Endogenous reverse transcripti ...... immunodeficiency virus type 1
@en
P2093
P2860
P1433
P1476
Endogenous reverse transcripti ...... immunodeficiency virus type 1
@en
P2093
P2860
P304
P407
P577
1996-08-01T00:00:00Z