Prolonged gene expression and cell survival after infection by a herpes simplex virus mutant defective in the immediate-early genes encoding ICP4, ICP27, and ICP22.
about
Utilizing ras signaling pathway to direct selective replication of herpes simplex virus-1.Herpes simplex virus type 1 vector-mediated expression of nerve growth factor protects dorsal root ganglion neurons from peroxide toxicityThe herpes simplex virus type 1 regulatory protein ICP27 is required for the prevention of apoptosis in infected human cells.ICP0 inhibits the decrease of HSV amplicon-mediated transgene expression.Persistence and expression of the herpes simplex virus genome in the absence of immediate-early proteins.Recombinant herpes simplex virus type 1 engineered for targeted binding to erythropoietin receptor-bearing cells.Long-term transgene expression in mice infected with a herpes simplex virus type 1 mutant severely impaired for immediate-early gene expression.Pseudotyping of glycoprotein D-deficient herpes simplex virus type 1 with vesicular stomatitis virus glycoprotein G enables mutant virus attachment and entry.Perturbation of cell cycle progression and cellular gene expression as a function of herpes simplex virus ICP0.Efficient activation of viral genomes by levels of herpes simplex virus ICP0 insufficient to affect cellular gene expression or cell survival.HSV-1-based vectors for gene therapy of neurological diseases and brain tumors: part II. Vector systems and applicationsThe dominant-negative herpes simplex virus type 1 (HSV-1) recombinant CJ83193 can serve as an effective vaccine against wild-type HSV-1 infection in mice.ICP0 is not required for efficient stress-induced reactivation of herpes simplex virus type 1 from cultured quiescently infected neuronal cells.Characterization of a potent refractory state and persistence of herpes simplex virus 1 in cell culture.Herpes simplex viral-vector design for efficient transduction of nonneuronal cells without cytotoxicity.The herpes simplex virus immediate-early protein ICP0 affects transcription from the viral genome and infected-cell survival in the absence of ICP4 and ICP27HSV ICP0 recruits USP7 to modulate TLR-mediated innate responseRegulatable gene expression systems for gene therapy applications: progress and future challenges.Use of Adeno-Associated and Herpes Simplex Viral Vectors for In Vivo Neuronal Expression in Mice.Herpes simplex virus ICP27 regulates alternative pre-mRNA polyadenylation and splicing in a sequence-dependent manner.Constitutive and Inducible Innate Responses in Cells Infected by HSV-1-Derived Amplicon Vectors.Viral vectors for gene delivery to the central nervous system.Recent gene therapy advancements for neurological diseases.Equine herpesvirus 1 gene 12 can substitute for vmw65 in the growth of herpes simplex virus (HSV) type 1, allowing the generation of optimized cell lines for the propagation of HSV vectors with multiple immediate-early gene defects.Mechanism of HSV infection through soluble adapter-mediated virus bridging to the EGF receptor.An enhanced packaging system for helper-dependent herpes simplex virus vectors.Development and optimization of herpes simplex virus vectors for multiple long-term gene delivery to the peripheral nervous system.Herpes simplex virus type 1 immediate-early protein Vmw110 inhibits progression of cells through mitosis and from G(1) into S phase of the cell cycle.Expression of herpes simplex virus ICP0 inhibits the induction of interferon-stimulated genes by viral infection.Immobilized cobalt affinity chromatography provides a novel, efficient method for herpes simplex virus type 1 gene vector purification.Repression of gene expression upon infection of cells with herpes simplex virus type 1 mutants impaired for immediate-early protein synthesis.A Herpesviral Immediate Early Protein Promotes Transcription Elongation of Viral Transcripts.Suppression of herpes simplex virus 1 in MDBK cells via the interferon pathway.Multiple immediate-early gene-deficient herpes simplex virus vectors allowing efficient gene delivery to neurons in culture and widespread gene delivery to the central nervous system in vivo.Specific destruction of kinetochore protein CENP-C and disruption of cell division by herpes simplex virus immediate-early protein Vmw110.Cell culture processes for the production of viral vectors for gene therapy purposes.Persistence of cyprinid herpesvirus 3 in infected cultured carp cells.And Then There Was Light: Perspectives of Optogenetics for Deep Brain Stimulation and Neuromodulation.Herpes Simplex Virus Vectors for Gene Transfer to the Central Nervous System
P2860
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P2860
Prolonged gene expression and cell survival after infection by a herpes simplex virus mutant defective in the immediate-early genes encoding ICP4, ICP27, and ICP22.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Prolonged gene expression and ...... coding ICP4, ICP27, and ICP22.
@ast
Prolonged gene expression and ...... coding ICP4, ICP27, and ICP22.
@en
type
label
Prolonged gene expression and ...... coding ICP4, ICP27, and ICP22.
@ast
Prolonged gene expression and ...... coding ICP4, ICP27, and ICP22.
@en
prefLabel
Prolonged gene expression and ...... coding ICP4, ICP27, and ICP22.
@ast
Prolonged gene expression and ...... coding ICP4, ICP27, and ICP22.
@en
P2093
P2860
P1433
P1476
Prolonged gene expression and ...... coding ICP4, ICP27, and ICP22.
@en
P2093
P2860
P304
P407
P577
1996-09-01T00:00:00Z