Transient subversion of CD40 ligand function diminishes immune responses to adenovirus vectors in mouse liver and lung tissues
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PEGylated Adenoviruses: From Mice to MonkeysCo-expression of sCD40LIg and CTLA4Ig mediated by adenovirus prolonged mouse skin allograft survival.Systemic and central nervous system correction of lysosomal storage in mucopolysaccharidosis type VII miceInjection of recombinant human type VII collagen corrects the disease phenotype in a murine model of dystrophic epidermolysis bullosa.In vitro and in vivo biology of recombinant adenovirus vectors with E1, E1/E2A, or E1/E4 deleted.Circumvention of immunity to the adenovirus major coat protein hexon.Combinatorial blockade of calcineurin and CD28 signaling facilitates primary and secondary therapeutic gene transfer by adenovirus vectors in dystrophic (mdx) mouse muscles.Transient inhibition of CD28 and CD40 ligand interactions prolongs adenovirus-mediated transgene expression in the lung and facilitates expression after secondary vector administrationVariability of human systemic humoral immune responses to adenovirus gene transfer vectors administered to different organsOvine adenovirus vectors overcome preexisting humoral immunity against human adenoviruses in vivo"Stealth" adenoviruses blunt cell-mediated and humoral immune responses against the virus and allow for significant gene expression upon readministration in the lungThe promise and potential hazards of adenovirus gene therapy.Construction and characterization of adenovirus serotype 5 packaged by serotype 3 hexon.Transduction of the mammary epithelium with adenovirus vectors in vivo.Current status of gene therapy for inherited lung diseasesGene therapy for dyslipidemia: a review of gene replacement and gene inhibition strategiesExpression of gp19K increases the persistence of transgene expression from an adenovirus vector in the mouse lung and liver.Transient immunomodulation with anti-CD40 ligand antibody and CTLA4Ig enhances persistence and secondary adenovirus-mediated gene transfer into mouse liver.The adenovirus E3/10.4K-14.5K proteins down-modulate the apoptosis receptor Fas/Apo-1 by inducing its internalization.A critical role for CD40-CD40 ligand interactions in amplification of the mucosal CD8 T cell responseLeukocyte-derived IL-10 reduces subepithelial fibrosis associated with chronically inhaled endotoxinGene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo.Platelets: essential components of the immune system.Targeting co-stimulatory pathways in gene therapyInhibition of NF-kappaB activation in combination with bcl-2 expression allows for persistence of first-generation adenovirus vectors in the mouse liverAdenovirus-mediated persistent cystic fibrosis transmembrane conductance regulator expression in mouse airway epithelium.Efficient, repeated adenovirus-mediated gene transfer in mice lacking both tumor necrosis factor alpha and lymphotoxin alpha.Readministration of adenovirus vector in nonhuman primate lungs by blockade of CD40-CD40 ligand interactionsPseudopackaging of adenovirus type 5 genomes into capsids containing the hexon proteins of adenovirus serotypes B, D, or E.Successful interference with cellular immune responses to immunogenic proteins encoded by recombinant viral vectors.Amelioration of collagen-induced arthritis by CD95 (Apo-1/Fas)-ligand gene transfer.Activation of transgene expression by early region 4 is responsible for a high level of persistent transgene expression from adenovirus vectors in vivo.Canine adenovirus vectors for lung-directed gene transfer: efficacy, immune response, and duration of transgene expression using helper-dependent vectors.Gene therapy for lung inflammatory diseases: not so far away?Effect of immunomodulation with anti-CD40L antibody on adenoviral-mediated transgene expression in mouse anterior segmentThe mouse cytomegalovirus glycoprotein m155 inhibits CD40 expression and restricts CD4 T cell responses.
P2860
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P2860
Transient subversion of CD40 ligand function diminishes immune responses to adenovirus vectors in mouse liver and lung tissues
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Transient subversion of CD40 l ...... n mouse liver and lung tissues
@ast
Transient subversion of CD40 l ...... n mouse liver and lung tissues
@en
type
label
Transient subversion of CD40 l ...... n mouse liver and lung tissues
@ast
Transient subversion of CD40 l ...... n mouse liver and lung tissues
@en
prefLabel
Transient subversion of CD40 l ...... n mouse liver and lung tissues
@ast
Transient subversion of CD40 l ...... n mouse liver and lung tissues
@en
P2093
P2860
P1433
P1476
Transient subversion of CD40 l ...... n mouse liver and lung tissues
@en
P2093
P2860
P304
P407
P577
1996-09-01T00:00:00Z