Persistent reovirus infections of L cells select mutations in viral attachment protein sigma1 that alter oligomer stability
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Potential for Improving Potency and Specificity of Reovirus Oncolysis with Next-Generation Reovirus VariantsThe GM2 Glycan Serves as a Functional Coreceptor for Serotype 1 ReovirusCleavage susceptibility of reovirus attachment protein sigma1 during proteolytic disassembly of virions is determined by a sequence polymorphism in the sigma1 neck.Reovirus growth in cell culture does not require the full complement of viral proteins: identification of a sigma1s-null mutant.Adaptation of reovirus to growth in the presence of protease inhibitor E64 segregates with a mutation in the carboxy terminus of viral outer-capsid protein sigma3.Identification of carbohydrate-binding domains in the attachment proteins of type 1 and type 3 reovirusesReovirus variants selected for resistance to ammonium chloride have mutations in viral outer-capsid protein sigma3.Attenuated reovirus displays oncolysis with reduced host toxicityReovirus variants selected during persistent infections of L cells contain mutations in the viral S1 and S4 genes and are altered in viral disassemblyMutations in reovirus outer-capsid protein sigma3 selected during persistent infections of L cells confer resistance to protease inhibitor E64A plasmid-based reverse genetics system for animal double-stranded RNA viruses.
P2860
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P2860
Persistent reovirus infections of L cells select mutations in viral attachment protein sigma1 that alter oligomer stability
description
1996 nî lūn-bûn
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1996年の論文
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1996年論文
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1996年論文
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1996年論文
@zh-hk
1996年論文
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1996年論文
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1996年论文
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1996年论文
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1996年论文
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name
Persistent reovirus infections ...... that alter oligomer stability
@ast
Persistent reovirus infections ...... that alter oligomer stability
@en
type
label
Persistent reovirus infections ...... that alter oligomer stability
@ast
Persistent reovirus infections ...... that alter oligomer stability
@en
prefLabel
Persistent reovirus infections ...... that alter oligomer stability
@ast
Persistent reovirus infections ...... that alter oligomer stability
@en
P2093
P2860
P1433
P1476
Persistent reovirus infections ...... that alter oligomer stability
@en
P2093
G J Wilson
J D Wetzel
R Bassel-Duby
T S Dermody
P2860
P304
P407
P577
1996-10-01T00:00:00Z