Generation of recombinant adenovirus vectors with modified fibers for altering viral tropism.
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Adenovirus gene transfer to amelogenesis imperfecta ameloblast-like cellsDevelopment of Novel Adenoviral Vectors to Overcome Challenges Observed With HAdV-5-based ConstructsAdenovirus vectors for gene therapy, vaccination and cancer gene therapyDevelopment of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adaptersPhage display of adenovirus type 5 fiber knob as a tool for specific ligand selection and validation.Improved gene delivery to intestinal mucosa by adenoviral vectors bearing subgroup B and d fibers.A strategy for adenovirus vector targeting with a secreted single chain antibody.A helper-independent adenovirus vector with E1, E3, and fiber deleted: structure and infectivity of fiberless particles.Ex vivo transfer of the Hoxc-8-interacting domain of Smad1 by a tropism-modified adenoviral vector results in efficient bone formation in a rabbit model of spinal fusion.Her2-specific multivalent adapters confer designed tropism to adenovirus for gene targetingAn adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism.Efficient gene transfer into human CD34(+) cells by a retargeted adenovirus vectorFiber swap between adenovirus subgroups B and C alters intracellular trafficking of adenovirus gene transfer vectors.A chimeric type 2 adenovirus vector with a type 17 fiber enhances gene transfer to human airway epitheliaChimeric adenoviral vectors incorporating a fiber of human adenovirus 3 efficiently mediate gene transfer into prostate cancer cells.Mutations in the DG loop of adenovirus type 5 fiber knob protein abolish high-affinity binding to its cellular receptor CAR.Adenovirus type 5 viral particles pseudotyped with mutagenized fiber proteins show diminished infectivity of coxsackie B-adenovirus receptor-bearing cells.A conditionally replicative adenovirus, CRAd-S-pK7, can target endometriosis with a cell-killing effectFiber-modified adenovirus for central nervous system Parkinson's disease gene therapy.Experimental virotherapy of chemoresistant pancreatic carcinoma using infectivity-enhanced fiber-mosaic oncolytic adenovirus.Adenoviral targeting using genetically incorporated camelid single variable domains.The promise and potential hazards of adenovirus gene therapy.Targeting of adenovirus via genetic modification of the viral capsid combined with a protein bridgeArtificial extension of the adenovirus fiber shaft inhibits infectivity in coxsackievirus and adenovirus receptor-positive cell lines.Modulation of adenovirus vector tropism via incorporation of polypeptide ligands into the fiber protein.Efficient amplification of chimeric adenovirus 5/40S vectors carrying the short fiber protein of Ad40 in suspension cell culturesAn adenovirus vector incorporating carbohydrate binding domains utilizes glycans for gene transfer.Mutation of the fiber shaft heparan sulphate binding site of a 5/3 chimeric adenovirus reduces liver tropism.Selectivity and efficiency of late transgene expression by transcriptionally targeted oncolytic adenoviruses are dependent on the transgene insertion strategy.Optimization of the helper-dependent adenovirus system for production and potency in vivo.A genetically engineered adenovirus vector targeted to CD40 mediates transduction of canine dendritic cells and promotes antigen-specific immune responses in vivoSpecies D human adenovirus type 9 exhibits better virus-spread ability for antitumor efficacy among alternative serotypes.Chapter One---Cancer terminator viruses and approaches for enhancing therapeutic outcomes.Gene Therapies for Cancer: Strategies, Challenges and Successes.Human papillomavirus type 18 chimeras containing the L2/L1 capsid genes from evolutionarily diverse papillomavirus types generate infectious virus.Mining the adenovirus virome for oncolytics against multiple solid tumor typesTransductional targeting of adenovirus vectors for gene therapyGene delivery into malignant glioma by infectivity-enhanced adenovirus: in vivo versus in vitro modelsA Multi Targeting Conditionally Replicating Adenovirus Displays Enhanced Oncolysis while Maintaining Expression of Immunotherapeutic Agents.Conditionally replicating adenoviruses for cancer treatment.
P2860
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P2860
Generation of recombinant adenovirus vectors with modified fibers for altering viral tropism.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Generation of recombinant aden ...... rs for altering viral tropism.
@ast
Generation of recombinant aden ...... rs for altering viral tropism.
@en
type
label
Generation of recombinant aden ...... rs for altering viral tropism.
@ast
Generation of recombinant aden ...... rs for altering viral tropism.
@en
prefLabel
Generation of recombinant aden ...... rs for altering viral tropism.
@ast
Generation of recombinant aden ...... rs for altering viral tropism.
@en
P2093
P2860
P1433
P1476
Generation of recombinant aden ...... ers for altering viral tropism
@en
P2093
D T Curiel
G V Mikheeva
J T Douglas
V N Krasnykh
P2860
P304
P407
P577
1996-10-01T00:00:00Z