Interaction of tau protein with model lipid membranes induces tau structural compaction and membrane disruption.
about
Roles of tau protein in health and disease.Tau binds to lipid membrane surfaces via short amphipathic helices located in its microtubule-binding repeatsImmunotherapeutic Approaches Targeting Amyloid-β, α-Synuclein, and Tau for the Treatment of Neurodegenerative Disorders.The fuzzy coat of pathological human Tau fibrils is a two-layered polyelectrolyte brush.A simple guide to biochemical approaches for analyzing protein-lipid interactions.Immunotherapy for neurodegenerative diseases: focus on α-synucleinopathies.Molecular understanding of a potential functional link between antimicrobial and amyloid peptides.Invited review: Drug development for tauopathies.Is membrane homeostasis the missing link between inflammation and neurodegenerative diseases?Protein/Peptide Aggregation and Amyloidosis on Biointerfaces.Extracellular monomeric tau protein is sufficient to initiate the spread of tau protein pathology.Difficulties associated with the structural analysis of proteins susceptible to form aggregates: The case of Tau protein as a biomarker of Alzheimer's disease.Formation and propagation of tau oligomeric seeds.Internalized Tau sensitizes cells to stress by promoting formation and stability of stress granulesStages and conformations of the Tau repeat domain during aggregation and its effect on neuronal toxicityStructural transitions in tau k18 on micelle binding suggest a hierarchy in the efficacy of individual microtubule-binding repeats in filament nucleation.Extracellular truncated tau causes early presynaptic dysfunction associated with Alzheimer's disease and other tauopathiesDiscovery and characterization of stable and toxic Tau/phospholipid oligomeric complexes.Interfacial Properties of NTAIL, an Intrinsically Disordered Protein.Trace Water as Prominent Factor to Induce Peptide Self-Assembly: Dynamic Evolution and Governing Interactions in Ionic Liquids.Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer's disease.Conformational Dynamics of Intracellular Tau Protein Revealed by CD and SAXS.The identification of raft-derived tau-associated vesicles that are incorporated into immature tangles and paired helical filaments.Recent applications of synchrotron radiation and neutrons in the study of soft matterPolyelectrolyte multilayers as a platform for pH-responsive lipid bilayers
P2860
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P2860
Interaction of tau protein with model lipid membranes induces tau structural compaction and membrane disruption.
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
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2012年论文
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name
Interaction of tau protein wit ...... ction and membrane disruption.
@ast
Interaction of tau protein wit ...... ction and membrane disruption.
@en
type
label
Interaction of tau protein wit ...... ction and membrane disruption.
@ast
Interaction of tau protein wit ...... ction and membrane disruption.
@en
prefLabel
Interaction of tau protein wit ...... ction and membrane disruption.
@ast
Interaction of tau protein wit ...... ction and membrane disruption.
@en
P2093
P2860
P356
P1433
P1476
Interaction of tau protein wit ...... ction and membrane disruption.
@en
P2093
Briana C Vernon
Emmalee M Jones
Jacek Biernat
Jaroslaw Majewski
Manish Dubey
Phillip J Camp
P2860
P304
P356
10.1021/BI201857V
P407
P577
2012-03-14T00:00:00Z