The early region 1B 55-kilodalton oncoprotein of adenovirus relieves growth restrictions imposed on viral replication by the cell cycle
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E1B 55-kilodalton-associated protein: a cellular protein with RNA-binding activity implicated in nucleocytoplasmic transport of adenovirus and cellular mRNAsOncolytic Replication of E1b-Deleted AdenovirusesTowards predictive computational models of oncolytic virus therapy: basis for experimental validation and model selection.Tumor associated stromal cells play a critical role on the outcome of the oncolytic efficacy of conditionally replicative adenovirusesRoles for the E4 orf6, orf3, and E1B 55-kilodalton proteins in cell cycle-independent adenovirus replication.Role of baculovirus IE2 and its RING finger in cell cycle arrest.p53 status does not determine outcome of E1B 55-kilodalton mutant adenovirus lytic infection.An arginine-faced amphipathic alpha helix is required for adenovirus type 5 e4orf6 protein functionp53-Independent and -dependent requirements for E1B-55K in adenovirus type 5 replication.Replicating adenoviruses that target tumors with constitutive activation of the wnt signaling pathwayReplication-selective adenoviruses as oncolytic agents.SUMO-1 modification required for transformation by adenovirus type 5 early region 1B 55-kDa oncoproteinDoes the antitumor adenovirus ONYX-015/dl1520 selectively target cells defective in the p53 pathway?Adenovirus E1B 55-kilodalton protein is required for both regulation of mRNA export and efficient entry into the late phase of infection in normal human fibroblastsE4orf6 variants with separate abilities to augment adenovirus replication and direct nuclear localization of the E1B 55-kilodalton protein.The human adenovirus type 5 E1B 55 kDa protein obstructs inhibition of viral replication by type I interferon in normal human cells.Postinternalization inhibition of adenovirus gene expression and infectious virus production in human T-cell linesExport of adenoviral late mRNA from the nucleus requires the Nxf1/Tap export receptor.Effects of mutations in the adenoviral E1B 55-kilodalton protein coding sequence on viral late mRNA metabolism.E4orf3 is necessary for enhanced S-phase replication of cell cycle-restricted subgroup C adenovirusesAdenovirus replaces mitotic checkpoint controls.Timely synthesis of the adenovirus type 5 E1B 55-kilodalton protein is required for efficient genome replication in normal human cells.Combination of a third generation bisphosphonate and replication-competent adenoviruses augments the cytotoxicity on mesothelioma.E4orf1 limits the oncolytic potential of the E1B-55K deletion mutant adenovirusGene therapy for bladder cancer using E1B-55 kD-deleted adenovirus in combination with adenoviral vector encoding plasminogen kringles 1-5.Adenovirus E1B 55-kilodalton protein: multiple roles in viral infection and cell transformation.Pharmacologic and chemical adjuvants in tumor virotherapy.Diverse roles for E4orf3 at late times of infection revealed in an E1B 55-kilodalton protein mutant background.Simultaneous Single-Cell In Situ Analysis of Human Adenovirus Type 5 DNA and mRNA Expression Patterns in Lytic and Persistent Infection.The replicative capacities of large E1B-null group A and group C adenoviruses are independent of host cell p53 statusAdenovirus type 5 E4orf3 protein relieves p53 inhibition by E1B-55-kilodalton protein.Replication of ONYX-015, a potential anticancer adenovirus, is independent of p53 status in tumor cells.The nuclear export signal within the E4orf6 protein of adenovirus type 5 supports virus replication and cytoplasmic accumulation of viral mRNA.Temporal regulation of the Mre11-Rad50-Nbs1 complex during adenovirus infection.Replication of an E1B 55-kilodalton protein-deficient adenovirus (ONYX-015) is restored by gain-of-function rather than loss-of-function p53 mutants.Adenovirus E1B55K region is required to enhance cyclin E expression for efficient viral DNA replication.Normal human cell proteins that interact with the adenovirus type 5 E1B 55kDa protein.Effects of febrile temperature on adenoviral infection and replication: implications for viral therapy of cancer.The products of the herpes simplex virus type 1 immediate-early US1/US1.5 genes downregulate levels of S-phase-specific cyclins and facilitate virus replication in S-phase Vero cells.
P2860
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P2860
The early region 1B 55-kilodalton oncoprotein of adenovirus relieves growth restrictions imposed on viral replication by the cell cycle
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
The early region 1B 55-kilodal ...... replication by the cell cycle
@ast
The early region 1B 55-kilodal ...... replication by the cell cycle
@en
type
label
The early region 1B 55-kilodal ...... replication by the cell cycle
@ast
The early region 1B 55-kilodal ...... replication by the cell cycle
@en
prefLabel
The early region 1B 55-kilodal ...... replication by the cell cycle
@ast
The early region 1B 55-kilodal ...... replication by the cell cycle
@en
P2860
P1433
P1476
The early region 1B 55-kilodal ...... replication by the cell cycle
@en
P2093
D A Ornelles
F D Goodrum
P2860
P304
P407
P577
1997-01-01T00:00:00Z