The replicative capacities of large E1B-null group A and group C adenoviruses are independent of host cell p53 status
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A role for E1B-AP5 in ATR signaling pathways during adenovirus infectionTumor-specific, replication-competent adenovirus vectors overexpressing the adenovirus death proteinp53-Independent and -dependent requirements for E1B-55K in adenovirus type 5 replication.Tissue-specific, tumor-selective, replication-competent adenovirus vector for cancer gene therapy.Replication-selective adenoviruses as oncolytic agents.ONYX-015: mechanisms of action and clinical potential of a replication-selective adenovirus.Does the antitumor adenovirus ONYX-015/dl1520 selectively target cells defective in the p53 pathway?Adenovirus E1B 55-kilodalton protein is required for both regulation of mRNA export and efficient entry into the late phase of infection in normal human fibroblastsGenetic identification of adenovirus type 5 genes that influence viral spread.The human adenovirus type 5 E1B 55 kDa protein obstructs inhibition of viral replication by type I interferon in normal human cells.Effects of mutations in the adenoviral E1B 55-kilodalton protein coding sequence on viral late mRNA metabolism.Chapter One---Cancer terminator viruses and approaches for enhancing therapeutic outcomes.Phase I clinical trial of locoregional administration of the oncolytic adenovirus ONYX-015 in combination with mitomycin-C, doxorubicin, and cisplatin chemotherapy in patients with advanced sarcomasAdenovirus ubiquitin-protein ligase stimulates viral late mRNA nuclear export.Timely synthesis of the adenovirus type 5 E1B 55-kilodalton protein is required for efficient genome replication in normal human cells.Reduced infectivity of adenovirus type 5 particles and degradation of entering viral genomes associated with incomplete processing of the preterminal protein.Adenovirus E1B 55-kilodalton protein: multiple roles in viral infection and cell transformation.Comparison of protein expression during wild-type, and E1B-55k-deletion, adenovirus infection using quantitative time-course proteomics.The nuclear export signal within the E4orf6 protein of adenovirus type 5 supports virus replication and cytoplasmic accumulation of viral mRNA.Evidence that replication of the antitumor adenovirus ONYX-015 is not controlled by the p53 and p14(ARF) tumor suppressor genes.Replication of an E1B 55-kilodalton protein-deficient adenovirus (ONYX-015) is restored by gain-of-function rather than loss-of-function p53 mutants.
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P2860
The replicative capacities of large E1B-null group A and group C adenoviruses are independent of host cell p53 status
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
The replicative capacities of ...... endent of host cell p53 status
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The replicative capacities of ...... ndent of host cell p53 status.
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The replicative capacities of ...... endent of host cell p53 status
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The replicative capacities of ...... ndent of host cell p53 status.
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The replicative capacities of ...... endent of host cell p53 status
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The replicative capacities of ...... ndent of host cell p53 status.
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P2093
P2860
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The replicative capacities of ...... endent of host cell p53 status
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P2093
A S Turnell
P H Gallimore
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1999-03-01T00:00:00Z