The cell surface glycoprotein CUB domain-containing protein 1 (CDCP1) contributes to epidermal growth factor receptor-mediated cell migration
about
EGFR regulates the development and microarchitecture of intratumoral angiogenic vasculature capable of sustaining cancer cell intravasation.Cell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer.Comparative proteomics of a model MCF10A-KRasG12V cell line reveals a distinct molecular signature of the KRasG12V cell surfaceNew crossroads for potential therapeutic intervention in cancer - intersections between CDCP1, EGFR family members and downstream signaling pathways.Elevated CDCP1 predicts poor patient outcome and mediates ovarian clear cell carcinoma by promoting tumor spheroid formation, cell migration and chemoresistance.EGF inhibits constitutive internalization and palmitoylation-dependent degradation of membrane-spanning procancer CDCP1 promoting its availability on the cell surface.HIF-2α regulates CDCP1 to promote PKCδ-mediated migration in hepatocellular carcinoma.ADAM9 enhances CDCP1 by inhibiting miR-1 through EGFR signaling activation in lung cancer metastasis.CD318 is a ligand for CD6.CDCP1 is a novel marker of the most aggressive human triple-negative breast cancers.Stratum basale keratinocyte expression of the cell-surface glycoprotein CDCP1 during epidermogenesis and its role in keratinocyte migration.The PDGFRβ/ERK1/2 pathway regulates CDCP1 expression in triple-negative breast cancer.Hypoxia-Inducible Factor 2-Dependent Pathways Driving Von Hippel-Lindau-Deficient Renal Cancer.
P2860
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P2860
The cell surface glycoprotein CUB domain-containing protein 1 (CDCP1) contributes to epidermal growth factor receptor-mediated cell migration
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
The cell surface glycoprotein ...... ceptor-mediated cell migration
@ast
The cell surface glycoprotein ...... ceptor-mediated cell migration
@en
type
label
The cell surface glycoprotein ...... ceptor-mediated cell migration
@ast
The cell surface glycoprotein ...... ceptor-mediated cell migration
@en
prefLabel
The cell surface glycoprotein ...... ceptor-mediated cell migration
@ast
The cell surface glycoprotein ...... ceptor-mediated cell migration
@en
P2093
P2860
P356
P1476
The cell surface glycoprotein ...... ceptor-mediated cell migration
@en
P2093
John W Lumley
Leonore de Boer
M Sharon Stack
P2860
P304
P356
10.1074/JBC.M111.335448
P407
P577
2012-02-07T00:00:00Z