A distal dimerization domain is essential for DNA-binding by the atypical HNF1 homeodomain
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HNF1alpha controls renal glucose reabsorption in mouse and man.Two members of an HNF1 homeoprotein family are expressed in human liverBcr interferes with beta-catenin-Tcf1 interactionA human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptorInteraction between the homeodomain proteins Cdx2 and HNF1alpha mediates expression of the lactase-phlorizin hydrolase geneMore potent transcriptional activators or a transdominant inhibitor of the HNF1 homeoprotein family are generated by alternative RNA processingThe X-ray structure of an atypical homeodomain present in the rat liver transcription factor LFB1/HNF1 and implications for DNA bindingThree-dimensional structure of the bifunctional protein PCD/DCoH, a cytoplasmic enzyme interacting with transcription factor HNF1Bi-allelic inactivation of TCF1 in hepatic adenomasLaron dwarfism and non-insulin-dependent diabetes mellitus in the Hnf-1alpha knockout mouse.LFB1/HNF1 acts as a repressor of its own transcriptionOxalate-inducible AMBP gene and its regulatory mechanism in renal tubular epithelial cellsvHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1Hepatocyte nuclear factor 1alpha controls the expression of terminal complement genesRole of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesisThe cnidarian-bilaterian ancestor possessed at least 56 homeoboxes: evidence from the starlet sea anemone, Nematostella vectensisStructure of the gene encoding hepatocyte nuclear factor 1 (HNF1)Functional interference between the Spi-1/PU.1 oncoprotein and steroid hormone or vitamin receptors.Regulation of albumin gene expression in hepatoma cells of fetal phenotype: dominant inhibition of HNF1 function and role of ubiquitous transcription factorsDiabetes-associated mutations in a beta-cell transcription factor destabilize an antiparallel "mini-zipper" in a dimerization interface.Hepatocyte nuclear factor-1β: A regulator of kidney development and cystogenesisAssociation of a low-frequency variant in HNF1A with type 2 diabetes in a Latino population.Independent regulation of HNF-1 alpha and HNF-1 beta by retinoic acid in F9 teratocarcinoma cells.Several different upstream promoter elements can potentiate transactivation by the BPV-1 E2 protein.Liver-specific expression of human insulin-like growth factor binding protein 1: functional role of transcription factor HNF1 in vivo.HNF4 and HNF1 as well as a panel of hepatic functions are extinguished and reexpressed in parallel in chromosomally reduced rat hepatoma-human fibroblast hybridsHepatocyte nuclear factor 1alpha gene inactivation impairs chromatin remodeling and demethylation of the phenylalanine hydroxylase geneDevelopmental regulation and tissue distribution of the liver transcription factor LFB1 (HNF1) in Xenopus laevis.Promoter-specific transactivation of hepatitis B virus transcription by a glutamine- and proline-rich domain of hepatocyte nuclear factor 1.Evidence for the identity of human scatter factor and human hepatocyte growth factor.Expression of the human gene coding for the alpha-chain of C4b-binding protein, C4BPA, is controlled by an HNF1-dependent hepatic-specific promoterEx vivo regulation of specific gene expression by nanomolar concentration of double-stranded dumbbell oligonucleotides.A POU-A related region dictates DNA binding specificity of LFB1/HNF1 by orienting the two XL-homeodomains in the dimer.Interplay of an original combination of factors: C/EBP, NFY, HNF3, and HNF1 in the rat aldolase B gene promoter.Crosslinking of double-stranded oligonucleotides containing O-methyl-substituted pyrophosphate groups to the HNF1 transcription factor in nuclear cell extract.An enhancer element 6 kb upstream of the mouse HNF4alpha1 promoter is activated by glucocorticoids and liver-enriched transcription factors.The HNF1/HNF4-dependent We2 element of woodchuck hepatitis virus controls viral replication and can activate the N-myc2 promoter.Liver-enriched transcription factors uncoupled from expression of hepatic functions in hepatoma cell lines.Purification and cDNA cloning of a transcription factor which functionally cooperates within a cAMP regulatory unit in the porcine uPA gene.An indirect negative autoregulatory mechanism involved in hepatocyte nuclear factor-1 gene expression.
P2860
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P2860
A distal dimerization domain is essential for DNA-binding by the atypical HNF1 homeodomain
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
A distal dimerization domain i ...... the atypical HNF1 homeodomain
@ast
A distal dimerization domain i ...... the atypical HNF1 homeodomain
@en
type
label
A distal dimerization domain i ...... the atypical HNF1 homeodomain
@ast
A distal dimerization domain i ...... the atypical HNF1 homeodomain
@en
prefLabel
A distal dimerization domain i ...... the atypical HNF1 homeodomain
@ast
A distal dimerization domain i ...... the atypical HNF1 homeodomain
@en
P2093
P2860
P356
P1476
A distal dimerization domain i ...... the atypical HNF1 homeodomain
@en
P2093
Blumenfeld M
Cereghini S
Vandekerckhove J
P2860
P304
P356
10.1093/NAR/18.19.5853
P407
P577
1990-10-01T00:00:00Z