A targeted RNAi screen of the breast cancer genome identifies KIF14 and TLN1 as genes that modulate docetaxel chemosensitivity in triple-negative breast cancer.
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KIF14 promotes AKT phosphorylation and contributes to chemoresistance in triple-negative breast cancerHitting the brakes: targeting microtubule motors in cancerReceptor-interacting protein kinase 2 promotes triple-negative breast cancer cell migration and invasion via activation of nuclear factor-kappaB and c-Jun N-terminal kinase pathways.Downregulation of Talin1 promotes hepatocellular carcinoma progression through activation of the ERK1/2 pathway.Kinesin family deregulation coordinated by bromodomain protein ANCCA and histone methyltransferase MLL for breast cancer cell growth, survival, and tamoxifen resistance.The role of KIF14 in patient-derived primary cultures of high-grade serous ovarian cancer cells.Genome-wide functional genomic and transcriptomic analyses for genes regulating sensitivity to vorinostat.High expression of Talin-1 is associated with poor prognosis in patients with nasopharyngeal carcinoma.Functional genomic screening approaches in mechanistic toxicology and potential future applications of CRISPR-Cas9.Both Talin-1 and Talin-2 correlate with malignancy potential of the human hepatocellular carcinoma MHCC-97 L cell.A genome scale RNAi screen identifies GLI1 as a novel gene regulating vorinostat sensitivity.Up-regulation of KIF14 is a predictor of poor survival and a novel prognostic biomarker of chemoresistance to paclitaxel treatment in cervical cancerCaveolin-1 Modulates Docetaxel-Induced Cell Death in Breast Cancer Cell Subtypes through Different MechanismsFilamin A (FLNA) modulates chemosensitivity to docetaxel in triple-negative breast cancer through the MAPK/ERK pathway.Cell matrix adhesions in cancer: The proteins that form the glue.Cationic Polymer Modified Mesoporous Silica Nanoparticles for Targeted SiRNA Delivery to HER2+ Breast Cancer.Kinesin superfamily: roles in breast cancer, patient prognosis and therapeutics.Biallelic variants in KIF14 cause intellectual disability with microcephaly.FLNA is a predictor of chemoresistance and poor survival in cervical cancer.KIF14 promotes cell proliferation via activation of Akt and is directly targeted by miR-200c in colorectal cancer
P2860
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P2860
A targeted RNAi screen of the breast cancer genome identifies KIF14 and TLN1 as genes that modulate docetaxel chemosensitivity in triple-negative breast cancer.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
A targeted RNAi screen of the ...... triple-negative breast cancer.
@ast
A targeted RNAi screen of the ...... triple-negative breast cancer.
@en
type
label
A targeted RNAi screen of the ...... triple-negative breast cancer.
@ast
A targeted RNAi screen of the ...... triple-negative breast cancer.
@en
prefLabel
A targeted RNAi screen of the ...... triple-negative breast cancer.
@ast
A targeted RNAi screen of the ...... triple-negative breast cancer.
@en
P2093
P2860
P1476
A targeted RNAi screen of the ...... triple-negative breast cancer.
@en
P2093
Crystal Cornelius
Gail Fasciani
Jerry W Shay
Kimberly Batten
Lawrence Lum
Stina Mui Singel
P2860
P304
P356
10.1158/1078-0432.CCR-13-0082
P407
P577
2013-03-11T00:00:00Z