AAA ATPase p97/VCP: cellular functions, disease and therapeutic potential.
about
Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductaseSVIP induces localization of p97/VCP to the plasma and lysosomal membranes and regulates autophagyFrom neurodevelopment to neurodegeneration: the interaction of neurofibromin and valosin-containing protein/p97 in regulation of dendritic spine formationCrystal structure of FAF1 UBX domain in complex with p97/VCP N domain reveals a conformational change in the conserved FcisP touch-turn motif of UBX domainThe Structural and Functional Basis of the p97/Valosin-containing Protein (VCP)-interacting Motif (VIM): MUTUALLY EXCLUSIVE BINDING OF COFACTORS TO THE N-TERMINAL DOMAIN OF p97Dendrimer-Based Selective Proteostasis-Inhibition Strategy to Control NSCLC Growth and ProgressionUnfolding the mechanism of the AAA+ unfoldase VAT by a combined cryo-EM, solution NMR study.Nanodelivery in airway diseases: challenges and therapeutic applications.Chaperone requirements for biosynthesis of the trypanosome variant surface glycoproteinEarly-age-related changes in proteostasis augment immunopathogenesis of sepsis and acute lung injury.Role of Cigarette Smoke-Induced Aggresome Formation in Chronic Obstructive Pulmonary Disease-Emphysema PathogenesisSterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from endoplasmic reticulum membranes into the cytosol through a subcellular compartment resembling lipid droplets.Retroviral Rem protein requires processing by signal peptidase and retrotranslocation for nuclear functionCritical role of VCP/p97 in the pathogenesis and progression of non-small cell lung carcinoma.Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductaseDevelopment of PEGylated PLGA nanoparticle for controlled and sustained drug delivery in cystic fibrosisp97-containing complexes in proliferation control and cancer: emerging culprits or guilt by association?Valosin-containing protein gene mutations: cellular phenotypes relevant to neurodegeneration.Combined inhibition of p97 and the proteasome causes lethal disruption of the secretory apparatus in multiple myeloma cells.The NF-kappaB signaling in cystic fibrosis lung disease: pathophysiology and therapeutic potentialProtein processing and inflammatory signaling in Cystic Fibrosis: challenges and therapeutic strategies.Critical role of proteostasis-imbalance in pathogenesis of COPD and severe emphysemaValosin-containing protein and neurofibromin interact to regulate dendritic spine densityThe ubiquitin regulatory X (UBX) domain-containing protein TUG regulates the p97 ATPase and resides at the endoplasmic reticulum-golgi intermediate compartment.Inhibitors of the AAA+ chaperone p97Novel mutation in VCP gene causes atypical amyotrophic lateral sclerosis.Role of p97/VCP (Cdc48) in genome stability.Valosin-containing protein (VCP) promotes the growth, invasion, and metastasis of colorectal cancer through activation of STAT3 signalingRequirements for the catalytic cycle of the N-ethylmaleimide-Sensitive Factor (NSF).Transcription Factor NF-κB: An Update on Intervention Strategies.Nano-based rescue of dysfunctional autophagy in chronic obstructive lung diseases.Crystallization and preliminary X-ray crystallographic analysis of the hexameric human p97/VCP ND1 fragment in complex with the UBX domain of human FAF1.Network-based identification of key proteins involved in apoptosis and cell cycle regulation.Nano-LC-MS/MS based proteomics of hepatocellular carcinoma cells compared to Chang liver cells and tanshinone IIA induction.Choice of biological source material supersedes oxidative stress in its influence on DJ-1 in vivo interactions with Hsp90.Crystallization and preliminary X-ray crystallographic analysis of the N domain of p97/VCP in complex with the UBX domain of FAF1.CXCL12/CXCR4-Mediated Procollagen Secretion Is Coupled To Cullin-RING Ubiquitin Ligase Activation.High expression of valosin-containing protein predicts poor prognosis in patients with breast carcinoma.Interaction between Smad1 and p97/VCP in rat testis and epididymis during the postnatal development.
P2860
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P2860
AAA ATPase p97/VCP: cellular functions, disease and therapeutic potential.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
AAA ATPase p97/VCP: cellular functions, disease and therapeutic potential.
@ast
AAA ATPase p97/VCP: cellular functions, disease and therapeutic potential.
@en
type
label
AAA ATPase p97/VCP: cellular functions, disease and therapeutic potential.
@ast
AAA ATPase p97/VCP: cellular functions, disease and therapeutic potential.
@en
prefLabel
AAA ATPase p97/VCP: cellular functions, disease and therapeutic potential.
@ast
AAA ATPase p97/VCP: cellular functions, disease and therapeutic potential.
@en
P2860
P1476
AAA ATPase p97/VCP: cellular functions, disease and therapeutic potential.
@en
P2093
Neeraj Vij
P2860
P304
P356
10.1111/J.1582-4934.2008.00462.X
P577
2008-08-09T00:00:00Z