about
Targeting p97 to Disrupt Protein Homeostasis in CancerRing of Change: CDC48/p97 Drives Protein Dynamics at ChromatinQuantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.Withaferin A Analogs That Target the AAA+ Chaperone p97.Selective inhibition of p97 by chlorinated analogues of dehydrocurvularinA Mighty "Protein Extractor" of the Cell: Structure and Function of the p97/CDC48 ATPase.Structure-Activity Study of Bioisosteric Trifluoromethyl and Pentafluorosulfanyl Indole Inhibitors of the AAA ATPase p97.Perturbation of cellular proteostasis networks identifies pathways that modulate precursor and intermediate but not mature levels of frataxinAllosteric Indole Amide Inhibitors of p97: Identification of a Novel Probe of the Ubiquitin Pathway.Dual Unnatural Amino Acid Incorporation and Click-Chemistry Labeling to Enable Single-Molecule FRET Studies of p97 Folding.Oxaspirol B with p97 Inhibitory Activity and Other Oxaspirols from Lecythophora sp. FL1375 and FL1031, Endolichenic Fungi Inhabiting Parmotrema tinctorum and Cladonia evansii.Affinity Purification of the Hepatitis C Virus Replicase Identifies Valosin-Containing Protein, a Member of the ATPases Associated with Diverse Cellular Activities Family, as an Active Virus Replication Modulator.Valosin-containing protein (VCP/p97) inhibitors relieve Mitofusin-dependent mitochondrial defects due to VCP disease mutants.Valosin-containing Protein is a Target of 5'-l Fuligocandin B and Enhances TRAIL Resistance in Cancer Cells.Strategic role of the ubiquitin-dependent segregase p97 (VCP or Cdc48) in DNA replication.A threonine turnstile defines a dynamic amphiphilic binding motif in the AAA ATPase p97 allosteric binding site.Proteomic Biomarkers for Bisphenol A-Early Exposure and Women's Thyroid Cancer.TRIP13 is expressed in colorectal cancer and promotes cancer cell invasion.Transmembrane helix hydrophobicity is an energetic barrier during the retrotranslocation of integral membrane ERAD substratesVCP inhibitors induce endoplasmic reticulum stress, cause cell cycle arrest, trigger caspase-mediated cell death and synergistically kill ovarian cancer cells in combination with Salubrinal.It's all about talking: two-way communication between proteasomal and lysosomal degradation pathways via ubiquitin.Correction: Chapman, E.; et al. Inhibitors of the AAA+ chaperone p97. Molecules 2015, 20, 3027-3049.A Non-Competitive Inhibitor of VCP/p97 and VPS4 Reveals Conserved Allosteric Circuits in Type I and II AAA ATPases.Evaluating p97 Inhibitor Analogues for Potency against p97-p37 and p97-Npl4-Ufd1 Complexes.Optimization of Phenyl Indole Inhibitors of the AAA+ ATPase p97
P2860
Q26740517-D0B8026F-8F2E-4DB1-AC12-E6B24243F15BQ26747328-18A53005-CE36-46F9-8A3F-0D0DE8FB93FCQ30826494-95223581-9916-4E9B-8DCE-265B3EE61D8EQ33360763-518A25BC-3E47-4B68-9D00-DFEE6E5A78BAQ33785301-2AE82DB6-F73C-439F-9F46-CD9E9A1C12DFQ33790385-A3C6BBDE-0E52-42FB-87FE-A46FF1BFF71AQ36367307-B93C15B9-5EA6-4986-930A-30CFCFD45E21Q36376219-7392A6B8-8490-42C1-A34B-10B9986919DCQ36579840-3F4D5BB2-392B-4F92-9A1E-3F73349DE4A8Q36997177-432BE39F-F381-49C1-AF2F-17F7BB5CFC65Q37051141-AE9C6438-8402-457A-AD1D-1C086A885B8DQ37347377-5E1DDFD5-4B4A-479A-A007-D7FD46D8067CQ37714188-FB376799-60E0-4E32-9581-AB806096DBA6Q38723897-73EF7055-AA4C-4C34-A09F-3128949B5F77Q38810286-54EEFDD2-7DA7-4FEE-9438-286F44BA70D8Q38869834-85132C30-B215-4A9B-AF2B-DA134A47C725Q40299522-ADE9208B-BBD9-497A-940D-ACFDB584895EQ41421424-DD750199-BCAD-4953-8753-33B71260B19AQ41662080-17627F91-2D6C-43D2-A988-D62157817946Q41895056-E9032017-347A-4B17-BC57-57F5962F3F55Q42361268-8DA1387C-AB75-49A5-A283-8F72083E1F25Q43120239-E9936842-42CE-4806-B691-2349F0346D2DQ47767635-DDC2B894-2842-4D24-AAFB-2600E15E6E05Q53161512-84354CDB-C5C7-47B1-80ED-82F29E29E6DCQ59133489-3445C986-DE7D-46FD-AA38-69BF54F87E76
P2860
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Inhibitors of the AAA+ chaperone p97
@ast
Inhibitors of the AAA+ chaperone p97
@en
type
label
Inhibitors of the AAA+ chaperone p97
@ast
Inhibitors of the AAA+ chaperone p97
@en
prefLabel
Inhibitors of the AAA+ chaperone p97
@ast
Inhibitors of the AAA+ chaperone p97
@en
P2093
P2860
P921
P1433
P1476
Inhibitors of the AAA+ chaperone p97
@en
P2093
Eli Chapman
Fabian de la Cruz
James J La Clair
Nick Maksim
P2860
P304
P356
10.3390/MOLECULES20023027
P407
P577
2015-02-12T00:00:00Z