Engineering upper hinge improves stability and effector function of a human IgG1.
about
Removal of a C-terminal serine residue proximal to the inter-chain disulfide bond of a human IgG1 lambda light chain mediates enhanced antibody stability and antibody dependent cell-mediated cytotoxicityRearranging the domain order of a diabody-based IgG-like bispecific antibody enhances its antitumor activity and improves its degradation resistance and pharmacokineticsAn anti-TNF-α antibody mimetic to treat ocular inflammation.Engineered protease-resistant antibodies with selectable cell-killing functions.An antibody with Fab-constant domains exchanged for a pair of CH3 domains.Fc-fusion mimetics.
P2860
Engineering upper hinge improves stability and effector function of a human IgG1.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Engineering upper hinge improves stability and effector function of a human IgG1.
@ast
Engineering upper hinge improves stability and effector function of a human IgG1.
@en
type
label
Engineering upper hinge improves stability and effector function of a human IgG1.
@ast
Engineering upper hinge improves stability and effector function of a human IgG1.
@en
prefLabel
Engineering upper hinge improves stability and effector function of a human IgG1.
@ast
Engineering upper hinge improves stability and effector function of a human IgG1.
@en
P2093
P2860
P356
P1476
Engineering upper hinge improves stability and effector function of a human IgG1.
@en
P2093
Amrita Kamath
Ashraf Amanullah
Bartek Nogal
Craig Emery
Daniel Boyd
Gabriele Schaefer
Gloria Y Meng
P2860
P304
P356
10.1074/JBC.M111.311811
P407
P577
2011-12-27T00:00:00Z