The lysophosphatidic acid receptor LPA1 promotes epithelial cell apoptosis after lung injury - Wikidata - wikimedia - TriplyDB

The lysophosphatidic acid receptor LPA1 promotes epithelial cell apoptosis after lung injury

The lysophosphatidic acid receptor LPA1 promotes epithelial cell apoptosis after lung injury

http://www.wikidata.org/entity/Q35889195

about

Lysophospholipids and their receptors in the central nervous system The Rho kinases: critical mediators of multiple profibrotic processes and rational targets for new therapies for pulmonary fibrosis Role of the autotaxin-lysophosphatidate axis in cancer resistance to chemotherapy and radiotherapy Role of the lysophospholipid mediators lysophosphatidic acid and sphingosine 1-phosphate in lung fibrosis.The mitochondrial cardiolipin remodeling enzyme lysocardiolipin acyltransferase is a novel target in pulmonary fibrosis.Design and synthesis of sulfamoyl benzoic acid analogues with subnanomolar agonist activity specific to the LPA2 receptor.Lysophosphatidic acid receptor 1 antagonist ki16425 blunts abdominal and systemic inflammation in a mouse model of peritoneal sepsis.Lysophosphatidic acid (LPA) and its receptors: role in airway inflammation and remodeling.Mitigation of radiation injury by selective stimulation of the LPA(2) receptor Virtual screening for LPA2-specific agonists identifies a nonlipid compound with antiapoptotic actions.Targeting sphingosine kinase 1 attenuates bleomycin-induced pulmonary fibrosis.Autotaxin activity increases locally following lung injury, but is not required for pulmonary lysophosphatidic acid production or fibrosis Lysophosphatidic Acid Signaling through the Lysophosphatidic Acid-1 Receptor Is Required for Alveolarization Fibrogenic Lung Injury Induces Non-Cell-Autonomous Fibroblast Invasion Sphingosine kinase 1 deficiency confers protection against hyperoxia-induced bronchopulmonary dysplasia in a murine model: role of S1P signaling and Nox proteins Destabilization of Lysophosphatidic Acid Receptor 1 Reduces Cytokine Release and Protects Against Lung Injury.Docosatetraenoyl LPA is elevated in exhaled breath condensate in idiopathic pulmonary fibrosis.Lysophosphatidic acid accelerates lung fibrosis by inducing differentiation of mesenchymal stem cells into myofibroblasts.Lysophosphatidic acid receptor-2 deficiency confers protection against bleomycin-induced lung injury and fibrosis in mice.Lysophosphatidic Acid Triggers Apoptosis in HeLa Cells through the Upregulation of Tumor Necrosis Factor Receptor Superfamily Member 21.Lysophosphatidic acid as a lipid mediator with multiple biological actions.Molecular mechanisms of target recognition by lipid GPCRs: relevance for cancer.Newer developments in idiopathic pulmonary fibrosis in the era of anti-fibrotic medications.Transforming growth factor β regulates β-catenin expression in lung fibroblast through NF-κB dependent pathway.Tissue remodelling in pulmonary fibrosis.The Role of Lysophosphatidic Acid on Airway Epithelial Cell Denudation in a Murine Heterotopic Tracheal Transplant Model Autotaxin emerges as a therapeutic target for idiopathic pulmonary fibrosis: limiting fibrosis by limiting lysophosphatidic acid synthesis Lysophosphatidic acid signaling through its receptor initiates profibrotic epithelial cell fibroblast communication mediated by epithelial cell derived connective tissue growth factor.The Rho Kinase Isoforms ROCK1 and ROCK2 Each Contribute to the Development of Experimental Pulmonary Fibrosis.Discovery of BI-2545: A Novel Autotaxin Inhibitor That Significantly Reduces LPA Levels in Vivo.Serum metabolic profiling identified a distinct metabolic signature in patients with idiopathic pulmonary fibrosis - a potential biomarker role for LysoPC.Regulation of silicosis formation by lysophosphatidic acid and its receptors.Expression of autotaxin and lysophosphatidic acid receptors 1 and 3 in the developing rat lung and in response to hyperoxia.Bone Marrow-Derived Mononuclear Cell Therapy in Papain-Induced Experimental Pulmonary Emphysema.Autotaxin in Pathophysiology and Pulmonary Fibrosis.

P2860

Q26859168-DCB2FBD7-880E-4B16-83B8-FC693108382E Q27005980-773AF000-901A-4941-AED8-BB7729B3FD90 Q27015257-81689A41-47B1-4BC0-BBC8-C9C30ABEFF72 Q33756825-50E5CC05-5195-4D64-88A2-6261346C3A11 Q33901590-ED3E8954-6012-4825-9899-3E2F26BBD0DF Q34104304-71B92C4B-9741-433E-8EAE-C6EB490FBE95 Q35691139-6718305D-6B68-4633-A2C0-F885E067CFF6 Q36377195-2DF123BD-122D-4A8A-807D-B7FBFF92DF96 Q36377955-A3FE23D2-D29D-4C2E-9342-C1F13B43C247 Q36412800-F856EDF8-4ED3-4356-B0BC-159F6E7A0D5C Q36710937-AED68BCE-DEA7-40EA-A99F-61A36F2240D4 Q36913763-31B14942-6F16-4E8C-B1DC-B1ABB6F10476 Q37088270-B120E9B2-9BC9-46EF-BED5-83932ABC7E14 Q37088303-9F58612B-38C4-42E8-A321-3F802A534B8B Q37218785-0A0D6A6B-64E6-4385-B0BB-C001897B10AB Q37221686-F38CBC38-3135-40A7-8625-4D5C4FD51908 Q37532276-15C5D1FB-2B81-4BC1-B84D-7A285440842D Q37562363-94C4D855-6094-4419-B478-3EB6CDC583CF Q37596497-E87BF362-D86B-4EB3-9ED4-E18FF21AC081 Q37700010-FE76F8B2-25B3-4B7D-A2FA-116405FF1C39 Q38286968-39EBD492-0946-43B0-B369-9AF47DA4A122 Q38660494-0BF88742-156A-4C19-9BF4-39FE9D31537C Q38812037-ACE0B960-A408-47DC-8986-4CEB5FEE9038 Q38961262-0E86F995-CBED-41A9-8ECD-EFA4F4F77AB3 Q39040828-A6DF45F7-CD0E-4883-B095-4CCE27EB9393 Q40584786-F1CDF73A-6F0D-47EB-AF29-05886AE553C7 Q42761894-E9E5B445-CE56-4FBD-956E-B1D11532DC0B Q45998425-FBB36B63-4408-4459-B593-C60DABA87519 Q47324079-8DB0DDB4-EA2D-4E1B-9C9E-0E891C7827F5 Q47676234-09F73D73-32CA-4FA1-962D-58625BF97310 Q48268746-E6F7FBAA-BF13-4AB0-B16D-A99CD3F60E47 Q50468824-5627BAE7-2AA1-4769-8934-CE6EC441BBE1 Q50577618-030558B9-E72E-42D8-9CC3-A63DA2E3E329 Q54974180-682AAE59-8994-46F8-B37E-A2DDBAD32C25 Q55420502-B8C5BDF1-D3C2-4D32-96C5-36E5FFA0422D

P2860

The lysophosphatidic acid receptor LPA1 promotes epithelial cell apoptosis after lung injury

http://www.wikidata.org/entity/Q35889195

description

2011 nî lūn-bûn

@nan

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

2011年论文

@zh

2011年论文

@zh-cn

name

The lysophosphatidic acid rece ...... ll apoptosis after lung injury

@ast

The lysophosphatidic acid rece ...... ll apoptosis after lung injury

@en

type

label

The lysophosphatidic acid rece ...... ll apoptosis after lung injury

@ast

The lysophosphatidic acid rece ...... ll apoptosis after lung injury

@en

prefLabel

The lysophosphatidic acid rece ...... ll apoptosis after lung injury

@ast

The lysophosphatidic acid rece ...... ll apoptosis after lung injury

@en

P1433

Q35889195-C4267305-3071-43B9-B0DD-A51C11805E26

P1476

Q35889195-07D6A84C-31BE-4129-9207-310EBD31EAAC

P2093

Q35889195-2AA1EEAA-968E-4817-89A7-988B8AE118B9

Q35889195-7B59B25B-3917-483E-BDEB-102A19DD0BB1

Q35889195-B20A7056-3E5A-4EC9-9219-6F4A6AE1461B

Q35889195-E2AF2B04-7448-4B94-B211-B4B4CE9562E6

Q35889195-F007FD3C-631E-433B-8ABF-730328C9FADE

P2860

Q35889195-019C05A5-D842-4650-9C98-3FE8F8DFF133

Q35889195-04D299DE-1BE1-4410-940E-C3BF25A27AEE

Q35889195-0C089F66-0F16-4A48-89E1-066E05D9F85F

Q35889195-0D998384-590D-4157-9FEC-09F14C8020B9

Q35889195-194AAE06-A35A-463B-BAD2-F810EAD0C14C

Q35889195-1AD89DDD-B6F8-4249-86D8-9A2F4D8C34E4

Q35889195-1B22BD81-A45D-4225-90E5-ADAF6ED8427D

Q35889195-1EDD9316-20E1-4454-9318-AAF5126DAC6D

Q35889195-27162AF5-9359-44FE-A773-9BBCA903630B

Q35889195-2A2EFFD2-F1FC-485F-B9B4-9DED597DE962

P304

Q35889195-776B5B3E-C2AF-49AB-973B-C4BBAF9083F4

P31

Q35889195-A8869E64-70BA-413B-85FF-523E5A38D88D

P356

Q35889195-0B48072C-D6FC-491B-9C96-AAFB55444B05

P433

Q35889195-EDC7A061-FE45-4253-AE50-BE735627F8CF

P478

Q35889195-A2294EBC-64C1-43E2-BF56-D64BDE378F85

P577

Q35889195-31B63948-E32E-4FF9-9DF8-F2C3B92269E3

P5875

Q35889195-81374A12-6C42-4C5A-B6A1-312022AA0D26

P698

Q35889195-AF8ABC7A-26ED-4022-9DF2-7AA9A309CEBF

P932

Q35889195-B60D5721-D946-448A-AC6E-168C951660D4

P356

RCMB.2010-0155OC

P1433

American Journal of Respiratory Cell and Molecular Biology

P1476

The lysophosphatidic acid rece ...... ll apoptosis after lung injury

@en

P2093

Andrew M Tager

http://www.w3.org/2001/XMLSchema#string

Jerold Chun

http://www.w3.org/2001/XMLSchema#string

Manuela Funke

http://www.w3.org/2001/XMLSchema#string

Yan Xu

http://www.w3.org/2001/XMLSchema#string

Zhenwen Zhao

http://www.w3.org/2001/XMLSchema#string

P2860

Disruption of epithelial cell-matrix interactions induces apoptosis

Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy

LPA receptors: subtypes and biological actions

Localisation of transforming growth factor beta1 and beta3 mRNA transcripts in normal and fibrotic human lung

Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix

Attenuation of bleomycin-induced pneumopathy in mice by a caspase inhibitor.

Diminished prostaglandin E2 contributes to the apoptosis paradox in idiopathic pulmonary fibrosis

Apoptosis and extracellular matrix-cell interactions in kidney disease.

Lysophosphatidic acid as a novel cell survival/apoptotic factor.

Combinatorial activation of FAK and AKT by transforming growth factor-beta1 confers an anoikis-resistant phenotype to myofibroblasts

P304

355-364

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1165/RCMB.2010-0155OC

http://www.w3.org/2001/XMLSchema#string

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

46

http://www.w3.org/2001/XMLSchema#string

P577

2011-10-20T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51736709

http://www.w3.org/2001/XMLSchema#string

P698

22021336

http://www.w3.org/2001/XMLSchema#string

P932

3326436

http://www.w3.org/2001/XMLSchema#string