The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer's disease.
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The endocannabinoid system in normal and pathological brain ageingThe rise of mitochondria in medicineAn overview on therapeutics attenuating amyloid β level in Alzheimer's disease: targeting neurotransmission, inflammation, oxidative stress and enhanced cholesterol levelsMitochondria-Targeted Protective Compounds in Parkinson's and Alzheimer's DiseasesMitochondrial abnormalities in Alzheimer's disease: possible targets for therapeutic interventionTargeting the prodromal stage of Alzheimer's disease: bioenergetic and mitochondrial opportunitiesA new chiral pyrrolyl α-nitronyl nitroxide radical attenuates β-amyloid deposition and rescues memory deficits in a mouse model of Alzheimer diseaseSenescence-accelerated OXYS rats: a model of age-related cognitive decline with relevance to abnormalities in Alzheimer disease.Mitochondria in Alzheimer's Disease and Diabetes-Associated Neurodegeneration: License to Heal!Mitoquinone restores platelet production in irradiation-induced thrombocytopenia.Altered Kv2.1 functioning promotes increased excitability in hippocampal neurons of an Alzheimer's disease mouse model.Mitochondrial DNA damage in a mouse model of Alzheimer's disease decreases amyloid beta plaque formationNew Therapeutics to Modulate Mitochondrial Function in Neurodegenerative Disorders.Oxidation of KCNB1 potassium channels triggers apoptotic integrin signaling in the brainRedox-based therapeutics in neurodegenerative disease.Mitochondria-derived reactive oxygen species mediate caspase-dependent and -independent neuronal deaths.The role of mitochondrial DNA mutation on neurodegenerative diseases.Centella asiatica Attenuates Amyloid-β-Induced Oxidative Stress and Mitochondrial DysfunctionRecent advances in the treatment of neurodegenerative diseases based on GSH delivery systems.Mitochondrial- and endoplasmic reticulum-associated oxidative stress in Alzheimer's disease: from pathogenesis to biomarkers.Posterior Cingulate Lactate as a Metabolic Biomarker in Amnestic Mild Cognitive Impairment.Indomethacin-induced translocation of bacteria across enteric epithelia is reactive oxygen species-dependent and reduced by vitamin C.Mitochondrial Superoxide Contributes to Hippocampal Synaptic Dysfunction and Memory Deficits in Angelman Syndrome Model MiceA mitochondrial redox oxygen sensor in the pulmonary vasculature and ductus arteriosusSelective Mitochondrial Targeting Exerts Anxiolytic Effects In Vivo.APP/PS1 mice overexpressing SREBP-2 exhibit combined Aβ accumulation and tau pathology underlying Alzheimer's disease.Tau accumulation impairs mitophagy via increasing mitochondrial membrane potential and reducing mitochondrial ParkinSTX, a Novel Membrane Estrogen Receptor Ligand, Protects Against Amyloid-β Toxicity.Mitochondrial-targeted peptide rapidly improves mitochondrial energetics and skeletal muscle performance in aged mice.Energy crisis precedes global metabolic failure in a novel Caenorhabditis elegans Alzheimer Disease model.AUTOPHAGY, MITOCHONDRIAL DYNAMICS AND RETINAL DISEASES.MitoQ, a mitochondria-targeted antioxidant, delays disease progression and alleviates pathogenesis in an experimental autoimmune encephalomyelitis mouse model of multiple sclerosis.Long-term administration of the mitochondria-targeted antioxidant mitoquinone mesylate fails to attenuate age-related oxidative damage or rescue the loss of muscle mass and function associated with aging of skeletal muscle.Oxidation of KCNB1 Potassium Channels Causes Neurotoxicity and Cognitive Impairment in a Mouse Model of Traumatic Brain Injury.Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics.P-glycoprotein (Mdr1a/1b) and breast cancer resistance protein (Bcrp) decrease the uptake of hydrophobic alkyl triphenylphosphonium cations by the brain.Epoxyeicosatrienoic acids pretreatment improves amyloid β-induced mitochondrial dysfunction in cultured rat hippocampal astrocytesEarly onset Alzheimer's disease and oxidative stress.Mitochondria-targeted antioxidants for treatment of Parkinson's disease: preclinical and clinical outcomes.Metabolic effects of a mitochondrial-targeted coenzyme Q analog in high fat fed obese mice.
P2860
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P2860
The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer's disease.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The mitochondria-targeted anti ...... model of Alzheimer's disease.
@ast
The mitochondria-targeted anti ...... model of Alzheimer's disease.
@en
type
label
The mitochondria-targeted anti ...... model of Alzheimer's disease.
@ast
The mitochondria-targeted anti ...... model of Alzheimer's disease.
@en
prefLabel
The mitochondria-targeted anti ...... model of Alzheimer's disease.
@ast
The mitochondria-targeted anti ...... model of Alzheimer's disease.
@en
P2860
P1476
The mitochondria-targeted anti ...... e model of Alzheimer's disease
@en
P2093
James L Franklin
Meagan J McManus
P2860
P304
15703-15715
P356
10.1523/JNEUROSCI.0552-11.2011
P407
P577
2011-11-01T00:00:00Z