Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist.

Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist.

Item
http://www.wikidata.org/entity/Q35910100
From Mollusks to Medicine: A Venomics Approach for the Discovery and Characterization of Therapeutics from Terebridae Peptide ToxinsIdentification of a Novel O-Conotoxin Reveals an Unusual and Potent Inhibitor of the Human α9α10 Nicotinic Acetylcholine Receptor(S)-lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology.Inhibition of α9α10 nicotinic acetylcholine receptors prevents chemotherapy-induced neuropathic pain.Screening and Validation of Highly-Efficient Insecticidal Conotoxins from a Transcriptome-Based Dataset of Chinese Tubular Cone Snail.α9-containing nicotinic acetylcholine receptors and the modulation of pain.αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtype.RgIA4 Potently Blocks Mouse α9α10 nAChRs and Provides Long Lasting Protection against Oxaliplatin-Induced Cold Allodynia.A novel α-conopeptide Eu1.6 inhibits N-type (CaV2.2) calcium channels and exhibits potent analgesic activity.Nicotinic acetylcholine receptors in neuropathic and inflammatory pain.Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer.Neuronal Nicotinic Acetylcholine Receptor Modulators from Cone Snails.
P2860

Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist.

Item
http://www.wikidata.org/entity/Q35910100
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Cloning, synthesis, and charac ...... ylcholine receptor antagonist.
@ast
Cloning, synthesis, and charac ...... ylcholine receptor antagonist.
@en
type
label
Cloning, synthesis, and charac ...... ylcholine receptor antagonist.
@ast
Cloning, synthesis, and charac ...... ylcholine receptor antagonist.
@en
prefLabel
Cloning, synthesis, and charac ...... ylcholine receptor antagonist.
@ast
Cloning, synthesis, and charac ...... ylcholine receptor antagonist.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Cloning, synthesis, and charac ...... tylcholine receptor antagonist
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932