Characterization of mutation spectra with ultra-deep pyrosequencing: application to HIV-1 drug resistance - Wikidata - wikimedia - TriplyDB

Characterization of mutation spectra with ultra-deep pyrosequencing: application to HIV-1 drug resistance

Characterization of mutation spectra with ultra-deep pyrosequencing: application to HIV-1 drug resistance

http://www.wikidata.org/entity/Q35914785

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Use of massively parallel pyrosequencing to evaluate the diversity of and selection on Plasmodium falciparum csp T-cell epitopes in Lilongwe, Malawi Exposing malaria in-host diversity and estimating population diversity by capture-recapture using massively parallel pyrosequencing.Viral quasispecies evolution New virologic tools for management of chronic hepatitis B and C SIV genome-wide pyrosequencing provides a comprehensive and unbiased view of variation within and outside CD8 T lymphocyte epitopes Accurate reconstruction of viral quasispecies spectra through improved estimation of strain richness The quasispecies nature and biological implications of the hepatitis C virus Viral population estimation using pyrosequencing HIV drug resistance surveillance using pooled pyrosequencing Rhinovirus genome evolution during experimental human infection.Prevalence and clinical significance of HIV drug resistance mutations by ultra-deep sequencing in antiretroviral-naïve subjects in the CASTLE study Dynamics of HIV-1 quasispecies during antiviral treatment dissected using ultra-deep pyrosequencing Low-abundance HIV drug-resistant viral variants in treatment-experienced persons correlate with historical antiretroviral use The evolutionary analysis of emerging low frequency HIV-1 CXCR4 using variants through time--an ultra-deep approach Which compound to select in lead optimization? Prospectively validated proteochemometric models guide preclinical development Minor HIV-1 variants with the K103N resistance mutation during intermittent efavirenz-containing antiretroviral therapy and virological failure Ultra-deep pyrosequencing detects conserved genomic sites and quantifies linkage of drug-resistant amino acid changes in the hepatitis B virus genome Base-calling algorithm with vocabulary (BCV) method for analyzing population sequencing chromatograms Deep sequencing analysis of HCV NS3 resistance-associated variants and mutation linkage in liver transplant recipients HIV-1 drug-resistance surveillance among treatment-experienced and -naïve patients after the implementation of antiretroviral therapy in Ghana Prevalence and evolution of low frequency HIV drug resistance mutations detected by ultra deep sequencing in patients experiencing first line antiretroviral therapy failure Prevalence of WHO transmitted drug resistance mutations by deep sequencing in antiretroviral-naïve subjects in Hunan Province, China Decreased phenotypic susceptibility to etravirine in patients with predicted genotypic sensitivity Contribution of human immunodeficiency virus type 1 minority variants to reduced drug susceptibility in patients on an integrase strand transfer inhibitor-based therapy Deep sequencing of protease inhibitor resistant HIV patient isolates reveals patterns of correlated mutations in Gag and protease Rapid and Simultaneous Detection of Major Drug Resistance Mutations in Reverse Transcriptase Gene for HIV-1 CRF01_AE, CRF07_BC and Subtype B in China Using Sequenom MassARRAY® System Simplified Paper Format for Detecting HIV Drug Resistance in Clinical Specimens by Oligonucleotide Ligation Mutations Related to Antiretroviral Resistance Identified by Ultra-Deep Sequencing in HIV-1 Infected Children under Structured Interruptions of HAART Simultaneous detection of major drug resistance mutations in the protease and reverse transcriptase genes for HIV-1 subtype C by use of a multiplex allele-specific assay Challenges and opportunities in estimating viral genetic diversity from next-generation sequencing data Development of a low bias method for characterizing viral populations using next generation sequencing technology Genome-wide mutational diversity in an evolving population of Escherichia coli Error baseline rates of five sample preparation methods used to characterize RNA virus populations Using high-throughput sequencing to leverage surveillance of genetic diversity and oseltamivir resistance: a pilot study during the 2009 influenza A(H1N1) pandemic.Sequential bottlenecks drive viral evolution in early acute hepatitis C virus infection.An outbreak of the 2009 influenza a (H1N1) virus in a children's hospital.Complete viral RNA genome sequencing of ultra-low copy samples by sequence-independent amplification Viral population analysis and minority-variant detection using short read next-generation sequencing.Antiviral drug resistance of human cytomegalovirus.Whole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection.

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Characterization of mutation spectra with ultra-deep pyrosequencing: application to HIV-1 drug resistance

http://www.wikidata.org/entity/Q35914785

description

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2007年论文

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Characterization of mutation s ...... ation to HIV-1 drug resistance

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Characterization of mutation s ...... ation to HIV-1 drug resistance

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Characterization of mutation s ...... ation to HIV-1 drug resistance

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Characterization of mutation s ...... ation to HIV-1 drug resistance

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Genome Research

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Characterization of mutation s ...... ation to HIV-1 drug resistance

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Baback Gharizadeh

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Chunlin Wang

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Mostafa Ronaghi

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Robert W Shafer

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Yumi Mitsuya

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P2860

Genome sequencing in microfabricated high-density picolitre reactors

Advanced sequencing technologies: methods and goals

HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy

Multiple, linked human immunodeficiency virus type 1 drug resistance mutations in treatment-experienced patients are missed by standard genotype analysis.

Oligonucleotide ligation assay for detecting mutations in the human immunodeficiency virus type 1 pol gene that are associated with resistance to zidovudine, didanosine, and lamivudine.

Changes in human immunodeficiency virus type 1 populations after treatment interruption in patients failing antiretroviral therapy.

Quantifying mixed populations of drug-resistant human immunodeficiency virus type 1.

The mitochondrial theory of aging and its relationship to reactive oxygen species damage and somatic mtDNA mutations.

Intrapartum exposure to nevirapine and subsequent maternal responses to nevirapine-based antiretroviral therapy.

Emergence of drug-resistant HIV-1 after intrapartum administration of single-dose nevirapine is substantially underestimated.

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1195-1201

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10.1101/GR.6468307

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8

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17

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17600086

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1933516

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