Cancer cells that survive radiation therapy acquire HIF-1 activity and translocate towards tumour blood vessels.
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Therapeutic Implications for Overcoming Radiation Resistance in Cancer TherapyHypoxia-inducible factor 1-mediated characteristic features of cancer cells for tumor radioresistanceDefining normoxia, physoxia and hypoxia in tumours-implications for treatment responseIdentification of Cys255 in HIF-1α as a novel site for development of covalent inhibitors of HIF-1α/ARNT PasB domain protein-protein interactionHIGD1A Regulates Oxygen Consumption, ROS Production, and AMPK Activity during Glucose Deprivation to Modulate Cell Survival and Tumor GrowthDormancy of cancer cells with suppression of AKT activity contributes to survival in chronic hypoxia.PLK1 blockade enhances therapeutic effects of radiation by inducing cell cycle arrest at the mitotic phase.Hypoxia-specific ultrasensitive detection of tumours and cancer cells in vivo.Role of HIF-1α in response of tumors to a combination of hyperthermia and radiation in vivo.Rituximab-including combined modality treatment for primary thyroid lymphoma: an effective regimen for elderly patientsHypoxia as a biomarker for radioresistant cancer stem cells.Aberrant IDH3α expression promotes malignant tumor growth by inducing HIF-1-mediated metabolic reprogramming and angiogenesis.BAY 87-2243, a novel inhibitor of hypoxia-induced gene activation, improves local tumor control after fractionated irradiation in a schedule-dependent manner in head and neck human xenograftsA cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells.UCHL1 provides diagnostic and antimetastatic strategies due to its deubiquitinating effect on HIF-1α.Unusual prolongation of radiation-induced G2 arrest in tumor xenografts derived from HeLa cellsMicroenvironments and cellular characteristics in the micro tumor cords of malignant solid tumorsHypoxia-Inducible Factor-1: A Critical Player in the Survival Strategy of Stressed Cells.In vivo self-bio-imaging of tumors through in situ biosynthesized fluorescent gold nanoclusters.Interleukin-33 enhances programmed oncosis of ST2L-positive low-metastatic cells in the tumour microenvironment of lung cancer.HIF-1-mediated metabolic reprogramming reduces ROS levels and facilitates the metastatic colonization of cancers in lungs.Improved sensitization effect of sunitinib in cancer cells of the esophagus under hypoxic microenviroment.Induction of metastasis, cancer stem cell phenotype, and oncogenic metabolism in cancer cells by ionizing radiation.LY6E: a conductor of malignant tumor growth through modulation of the PTEN/PI3K/Akt/HIF-1 axis.Heparanase promotes radiation resistance of cervical cancer by upregulating hypoxia inducible factor 1.The impact of tumor microenvironment on cancer treatment and its modulation by direct and indirect antivascular strategies.Microenvironment and radiation therapyRadiation oncology in vitro: trends to improve radiotherapy through molecular targets.Tumor hypoxia: a new PET imaging biomarker in clinical oncology.UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization.Development of a real-time imaging system for hypoxic cell apoptosis.CRLX101, a Nanoparticle-Drug Conjugate Containing Camptothecin, Improves Rectal Cancer Chemoradiotherapy by Inhibiting DNA Repair and HIF1α.Inhibition of Glut1 by WZB117 sensitizes radioresistant breast cancer cells to irradiation.The expression level of the transcription factor Aryl hydrocarbon receptor nuclear translocator (ARNT) determines cellular survival after radiation treatment.Reducing radiation-induced gastrointestinal toxicity - the role of the PHD/HIF axis.DNA-PKcs deficiency inhibits glioblastoma cell-derived angiogenesis after ionizing radiation.Hypoxia: A Double-Edged Sword in Cancer Therapy.Berberine enhances radiosensitivity of esophageal squamous cancer by targeting HIF-1α in vitro and in vivo.The induction of MIG6 under hypoxic conditions is critical for dormancy in primary cultured lung cancer cells with activating EGFR mutations.A highly selective near-infrared fluorescent probe for imaging H2Se in living cells and in vivo.
P2860
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P2860
Cancer cells that survive radiation therapy acquire HIF-1 activity and translocate towards tumour blood vessels.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Cancer cells that survive radi ...... towards tumour blood vessels.
@ast
Cancer cells that survive radi ...... towards tumour blood vessels.
@en
type
label
Cancer cells that survive radi ...... towards tumour blood vessels.
@ast
Cancer cells that survive radi ...... towards tumour blood vessels.
@en
prefLabel
Cancer cells that survive radi ...... towards tumour blood vessels.
@ast
Cancer cells that survive radi ...... towards tumour blood vessels.
@en
P2093
P2860
P356
P1476
Cancer cells that survive radi ...... towards tumour blood vessels.
@en
P2093
Akiyo Morinibu
Guangfei Ou
Hiroshi Harada
Kazumi Shinomiya
Lihua Zeng
Masahiro Hiraoka
Masahiro Inoue
Michio Yoshimura
Ruth J Muschel
Satoshi Itasaka
P2860
P2888
P356
10.1038/NCOMMS1786
P407
P50
P577
2012-04-17T00:00:00Z