Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins.
about
Protein phosphorylation cascades associated with methamphetamine-induced glial activation.mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4ESignaling by target of rapamycin proteins in cell growth controlFunctional interaction between RAFT1/FRAP/mTOR and protein kinase cdelta in the regulation of cap-dependent initiation of translationS6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathwayCoupling of cell division to cell growth by translational control of the G1 cyclin CLN3 in yeastUpdates of mTOR inhibitorsDual requirement for a newly identified phosphorylation site in p70s6kOvercoming cisplatin resistance by mTOR inhibitor in lung cancer.The role and regulation of mTOR in T-lymphocyte functionEnhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.TOR controls translation initiation and early G1 progression in yeastLongevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intakeExpression of human mitochondrial NADP-dependent isocitrate dehydrogenase during lymphocyte activationLa-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1)Regulation of the rapamycin and FKBP-target 1/mammalian target of rapamycin and cap-dependent initiation of translation by the c-Abl protein-tyrosine kinaseCharacterization of S6K2, a novel kinase homologous to S6K1ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathwayRapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translationInactivation of eIF2B and phosphorylation of PHAS-I in heat-shocked rat hepatoma cellsImpaired overload-induced muscle growth is associated with diminished translational signalling in aged rat fast-twitch skeletal muscleControl of PHAS-I by insulin in 3T3-L1 adipocytes. Synthesis, degradation, and phosphorylation by a rapamycin-sensitive and mitogen-activated protein kinase-independent pathwayAmino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanismTOR signaling.Amino acid-induced translation of TOP mRNAs is fully dependent on phosphatidylinositol 3-kinase-mediated signaling, is partially inhibited by rapamycin, and is independent of S6K1 and rpS6 phosphorylationS6 phosphorylation-independent pathways regulate translation of 5'-terminal oligopyrimidine tract-containing mRNAs in differentiating hematopoietic cells.Genome-wide assessment of differential translations with ribosome profiling data.Comparative sequence analysis of the complete set of 40S ribosomal proteins in the Senegalese sole (Solea senegalensis Kaup) and Atlantic halibut (Hippoglossus hippoglossus L.) (Teleostei: Pleuronectiformes): phylogeny and tissue- and development-spRapamycin inhibits clonal expansion and adipogenic differentiation of 3T3-L1 cellsRibosomal protein S6 kinase is a critical downstream effector of the target of rapamycin complex 1 for long-term facilitation in Aplysia.Discovery of novel interacting partners of PSMD9, a proteasomal chaperone: Role of an Atypical and versatile PDZ-domain motif interaction and identification of putative functional modulesLuteinizing hormone stimulates mammalian target of rapamycin signaling in bovine luteal cells via pathways independent of AKT and mitogen-activated protein kinase: modulation of glycogen synthase kinase 3 and AMP-activated protein kinase14-3-3tau associates with a translational control factor FKBP12-rapamycin-associated protein in T-cells after stimulation by pervanadate.Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase.Translational control of viral gene expression in eukaryotesDown-regulation of RpS21, a putative translation initiation factor interacting with P40, produces viable minute imagos and larval lethality with overgrown hematopoietic organs and imaginal discs.p70(S6K) controls selective mRNA translation during oocyte maturation and early embryogenesis in Xenopus laevis.A heat-sensitive Arabidopsis thaliana kinase substitutes for human p70s6k function in vivo.Rapamycin selectively reduces the association of transcripts containing complex 5' UTRs with ribosomes in C4-2B prostate cancer cells.cAMP- and rapamycin-sensitive regulation of the association of eukaryotic initiation factor 4E and the translational regulator PHAS-I in aortic smooth muscle cells.
P2860
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P2860
Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Rapamycin selectively inhibits ...... actors and ribosomal proteins.
@ast
Rapamycin selectively inhibits ...... actors and ribosomal proteins.
@en
type
label
Rapamycin selectively inhibits ...... actors and ribosomal proteins.
@ast
Rapamycin selectively inhibits ...... actors and ribosomal proteins.
@en
prefLabel
Rapamycin selectively inhibits ...... actors and ribosomal proteins.
@ast
Rapamycin selectively inhibits ...... actors and ribosomal proteins.
@en
P2093
P2860
P356
P1476
Rapamycin selectively inhibits ...... actors and ribosomal proteins.
@en
P2093
P2860
P304
11477-11481
P356
10.1073/PNAS.91.24.11477
P407
P577
1994-11-01T00:00:00Z