4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
about
Heat generates oxidized linoleic acid metabolites that activate TRPV1 and produce pain in rodentsSpecies-specific pharmacology of Trichloro(sulfanyl)ethyl benzamides as transient receptor potential ankyrin 1 (TRPA1) antagonistsDiacetyl increases sensory innervation and substance P production in rat tracheaThe search for novel analgesics: targets and mechanismsA gain-of-function mutation in TRPA1 causes familial episodic pain syndromeStructure of the TRPA1 ion channel suggests regulatory mechanismsUnusual pungency from extra-virgin olive oil is attributable to restricted spatial expression of the receptor of oleocanthalInternational Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel familyTransient receptor potential (TRP) channels as drug targets for diseases of the digestive systemChemokines and the pathophysiology of neuropathic painSpecies-specific temperature sensitivity of TRPA1Current understanding of the neuropathophysiology of pain in chronic pancreatitisHow the TRPA1 receptor transmits painful stimuli: Inner workings revealed by electron cryomicroscopyRole of oxidative stress & transient receptor potential in chronic obstructive pulmonary diseaseDeciphering Subtype-Selective Modulations in TRPA1 Biosensor ChannelsThe TRPA1 channel in migraine mechanism and treatmentThe role of TRPA1 in visceral inflammation and painTRPA1 channels in the vasculatureUpregulation of the transient receptor potential ankyrin 1 ion channel in the inflamed human and mouse colon and its protective rolesA Tarantula-Venom Peptide Antagonizes the TRPA1 Nociceptor Ion Channel by Binding to the S1–S4 Gating DomainBlocking TRPA1 in Respiratory Disorders: Does It Hold a Promise?Neurogenic inflammation after traumatic brain injury and its potentiation of classical inflammationNociceptive TRP Channels: Sensory Detectors and Transducers in Multiple Pain PathologiesTransient receptor potential channels as therapeutic targetsSpinal 12-lipoxygenase-derived hepoxilin A3 contributes to inflammatory hyperalgesia via activation of TRPV1 and TRPA1 receptorsThe concept of neurogenic inflammationAcute cardiopulmonary toxicity of inhaled aldehydes: role of TRPA1TRPA1 mediates mechanical sensitization in nociceptors during inflammationMethylglyoxal evokes pain by stimulating TRPA1Differential Contribution of TRPA1, TRPV4 and TRPM8 to Colonic Nociception in MiceExpression of transient receptor potential ankyrin 1 (TRPA1) and its role in insulin release from rat pancreatic beta cellsTRPA1 contributes to cold hypersensitivityWarmth suppresses and desensitizes damage-sensing ion channel TRPA1TRPA1 is a major oxidant sensor in murine airway sensory neuronsGeneral anesthetics activate a nociceptive ion channel to enhance pain and inflammationActivation of transient receptor potential ankyrin-1 (TRPA1) in lung cells by wood smoke particulate materialTerpenes and lipids of the endocannabinoid and transient-receptor-potential-channel biosignaling systemsNeurogenic Inflammation – The Peripheral Nervous System’s Role in Host Defense and ImmunopathologyCellular and Molecular Mechanisms of PainRole of TRPA1 in Acute Cardiopulmonary Toxicity of Inhaled Acrolein
P2860
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P2860
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
4-Hydroxynonenal, an endogenou ...... of the irritant receptor TRPA1
@ast
4-Hydroxynonenal, an endogenou ...... of the irritant receptor TRPA1
@en
type
label
4-Hydroxynonenal, an endogenou ...... of the irritant receptor TRPA1
@ast
4-Hydroxynonenal, an endogenou ...... of the irritant receptor TRPA1
@en
prefLabel
4-Hydroxynonenal, an endogenou ...... of the irritant receptor TRPA1
@ast
4-Hydroxynonenal, an endogenou ...... of the irritant receptor TRPA1
@en
P2093
P2860
P356
P1476
4-Hydroxynonenal, an endogenou ...... of the irritant receptor TRPA1
@en
P2093
Allan I Basbaum
Barbara Campi
David Julius
Diana M Bautista
Graeme S Cottrell
Jan Siemens
Marcello Trevisani
Nigel W Bunnett
Noritaka Imamachi
Pierangelo Geppetti
P2860
P304
13519-13524
P356
10.1073/PNAS.0705923104
P407
P50
P577
2007-08-07T00:00:00Z