HIV-1 Nef-induced down-regulation of MHC class I requires AP-1 and clathrin but not PACS-1 and is impeded by AP-2.
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Trafficking of vesicular neurotransmitter transportersForty Years of Clathrin-coated VesiclesExosomes: Implications in HIV-1 PathogenesisIntracellular Transport Routes for MHC I and Their Relevance for Antigen Cross-PresentationConformation of the dileucine-based sorting motif in HIV-1 Nef revealed by intermolecular domain assemblyHIV-1 Nef inhibits Protease activity and its absence alters protein content of mature viral particlesTE-domestication and horizontal transfer in a putative Nef-AP1mu mimic of HLA-A cytoplasmic domain re-trafficking.HIV-1 Nef targets MHC-I and CD4 for degradation via a final common beta-COP-dependent pathway in T cells.The Epstein-Barr virus G-protein-coupled receptor contributes to immune evasion by targeting MHC class I molecules for degradationRapid inactivation of proteins by rapamycin-induced rerouting to mitochondriaHIV-1 Nef binds a subpopulation of MHC-I throughout its trafficking itinerary and down-regulates MHC-I by perturbing both anterograde and retrograde trafficking.A cytoplasmic tail determinant in HIV-1 Vpu mediates targeting of tetherin for endosomal degradation and counteracts interferon-induced restriction.Interaction of HIV-1 Nef protein with the host protein Alix promotes lysosomal targeting of CD4 receptor.Intracellular overexpression of HIV-1 Nef impairs differentiation and maturation of monocytic precursors towards dendritic cellsCargo recognition in clathrin-mediated endocytosisNef neutralizes the ability of exosomes from CD4+ T cells to act as decoys during HIV-1 infection.At the crossroads of homoeostasis and disease: roles of the PACS proteins in membrane traffic and apoptosis.Adaptor protein complexes AP-1 and AP-3 are required by the HHV-7 Immunoevasin U21 for rerouting of class I MHC molecules to the lysosomal compartment.ADP ribosylation factor 1 activity is required to recruit AP-1 to the major histocompatibility complex class I (MHC-I) cytoplasmic tail and disrupt MHC-I trafficking in HIV-1-infected primary T cells.A Genome-Wide Screen for Machinery Involved in Downregulation of MHC Class I by HIV-1 Nef.A noncanonical mu-1A-binding motif in the N terminus of HIV-1 Nef determines its ability to downregulate major histocompatibility complex class I in T lymphocytesSorting of Clathrin-Independent Cargo Proteins Depends on Rab35 Delivered by Clathrin-Mediated EndocytosisNef promotes evasion of human immunodeficiency virus type 1-infected cells from the CTLA-4-mediated inhibition of T-cell activation.Cooperative binding of the class I major histocompatibility complex cytoplasmic domain and human immunodeficiency virus type 1 Nef to the endosomal AP-1 complex via its mu subunitA diacidic motif in human immunodeficiency virus type 1 Nef is a novel determinant of binding to AP-2HIV-1 Nef binds PACS-2 to assemble a multikinase cascade that triggers major histocompatibility complex class I (MHC-I) down-regulation: analysis using short interfering RNA and knock-out mice.The subcellular distribution of calnexin is mediated by PACS-2Functional characterization of the human immunodeficiency virus type 1 Nef acidic domain.Auxilin depletion causes self-assembly of clathrin into membraneless cages in vivoA basic patch on alpha-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex.p53 increases MHC class I expression by upregulating the endoplasmic reticulum aminopeptidase ERAP1Mechanisms of HIV-1 Nef function and intracellular signaling.Human immunodeficiency virus type 1 Nef protein targets CD4 to the multivesicular body pathway.Immune responses to Epstein-Barr virus: molecular interactions in the virus evasion of CD8+ T cell immunityHIV immune evasion disruption of antigen presentation by the HIV Nef protein.The natural killer cell cytotoxic function is modulated by HIV-1 accessory proteins.The activity of Nef on HIV-1 infectivityRedundant roles of BIG2 and BIG1, guanine-nucleotide exchange factors for ADP-ribosylation factors in membrane traffic between the trans-Golgi network and endosomesHIV-1 Nef: Taking Control of Protein Trafficking.Human immunodeficiency virus type 1 nef expression prevents AP-2-mediated internalization of the major histocompatibility complex class II-associated invariant chain.
P2860
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P2860
HIV-1 Nef-induced down-regulation of MHC class I requires AP-1 and clathrin but not PACS-1 and is impeded by AP-2.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
HIV-1 Nef-induced down-regulat ...... PACS-1 and is impeded by AP-2.
@ast
HIV-1 Nef-induced down-regulat ...... PACS-1 and is impeded by AP-2.
@en
type
label
HIV-1 Nef-induced down-regulat ...... PACS-1 and is impeded by AP-2.
@ast
HIV-1 Nef-induced down-regulat ...... PACS-1 and is impeded by AP-2.
@en
prefLabel
HIV-1 Nef-induced down-regulat ...... PACS-1 and is impeded by AP-2.
@ast
HIV-1 Nef-induced down-regulat ...... PACS-1 and is impeded by AP-2.
@en
P2093
P2860
P356
P1476
HIV-1 Nef-induced down-regulat ...... PACS-1 and is impeded by AP-2.
@en
P2093
Alison M Motley
Daniela A Sahlender
Margaret S Robinson
Nienke B Lubben
Paul J Lehner
Philippe Benaroch
P2860
P304
P356
10.1091/MBC.E07-03-0218
P577
2007-06-20T00:00:00Z