Prodigiosin rescues deficient p53 signaling and antitumor effects via upregulating p73 and disrupting its interaction with mutant p53.
about
P53 mutations in colorectal cancer - molecular pathogenesis and pharmacological reactivationTAp73 promotes anabolismSmall-Molecule Reactivation of Mutant p53 to Wild-Type-like p53 through the p53-Hsp40 Regulatory AxisAnalysis of the genomic sequences and metabolites of Serratia surfactantfaciens sp. nov. YD25(T) that simultaneously produces prodigiosin and serrawettin W2.Prodigiosin inhibits Wnt/β-catenin signaling and exerts anticancer activity in breast cancer cells.A balancing act: orchestrating amino-truncated and full-length p73 variants as decisive factors in cancer progression.Inhibitory Growth of Oral Squamous Cell Carcinoma Cancer via Bacterial Prodigiosin.Prodigiosin and its potential applicationsCurcumol triggers apoptosis of p53 mutant triple-negative human breast cancer MDA-MB 231 cells via activation of p73 and PUMA.Reviving the guardian of the genome: Small molecule activators of p53.Understanding cell cycle and cell death regulation provides novel weapons against human diseases.Natural Compounds from Herbs that can Potentially Execute as Autophagy Inducers for Cancer Therapy.P53 deficiency-induced Smad1 upregulation suppresses tumorigenesis and causes chemoresistance in colorectal cancers.p53 family members regulate cancer stem cells.Targeting mutant p53 for cancer therapy.4th international conference on tumor progression and therapeutic resistance: meeting report.CB002, a novel p53 tumor suppressor pathway-restoring small molecule induces tumor cell death through the pro-apoptotic protein NOXA.New therapeutic strategies to treat human cancers expressing mutant p53 proteins.Regulation of p53 and survivin by prodigiosin compound derived from Serratia marcescens contribute to caspase-3-dependent apoptosis in acute lymphoblastic leukemia cells.Gain-of-Function (GOF) Mutant p53 as Actionable Therapeutic Target.
P2860
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P2860
Prodigiosin rescues deficient p53 signaling and antitumor effects via upregulating p73 and disrupting its interaction with mutant p53.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
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2013年论文
@zh-cn
name
Prodigiosin rescues deficient ...... s interaction with mutant p53.
@ast
Prodigiosin rescues deficient ...... s interaction with mutant p53.
@en
type
label
Prodigiosin rescues deficient ...... s interaction with mutant p53.
@ast
Prodigiosin rescues deficient ...... s interaction with mutant p53.
@en
prefLabel
Prodigiosin rescues deficient ...... s interaction with mutant p53.
@ast
Prodigiosin rescues deficient ...... s interaction with mutant p53.
@en
P2093
P2860
P1433
P1476
Prodigiosin rescues deficient ...... s interaction with mutant p53.
@en
P2093
A Pieter J van den Heuvel
David T Dicker
Levy Kopelovich
Shengliang Zhang
Varun V Prabhu
P2860
P304
P356
10.1158/0008-5472.CAN-13-0955
P407
P577
2013-11-18T00:00:00Z