PAK and other Rho-associated kinases--effectors with surprisingly diverse mechanisms of regulation - Wikidata - wikimedia - TriplyDB

PAK and other Rho-associated kinases--effectors with surprisingly diverse mechanisms of regulation

PAK and other Rho-associated kinases--effectors with surprisingly diverse mechanisms of regulation

http://www.wikidata.org/entity/Q35952627

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HGAL, a germinal center specific protein, decreases lymphoma cell motility by modulation of the RhoA signaling pathway The Rac1 polybasic region is required for interaction with its effector PRK1 Inhibition of cell migration by autophosphorylated mammalian sterile 20-like kinase 3 (MST3) involves paxillin and protein-tyrosine phosphatase-PEST Pak1 regulates branching morphogenesis in 3D MDCK cell culture by a PIX and beta1-integrin-dependent mechanism Mixed lineage kinase phosphorylates transcription factor E47 and inhibits TrkB expression to link neuronal death and survival pathways Group I and II mammalian PAKs have different modes of activation by Cdc42 Co-crystal structures of inhibitors with MRCKβ, a key regulator of tumor cell invasion Rac GTPase signaling through the PP5 protein phosphatase Pak1 and Pak2 are activated in recurrent respiratory papillomas, contributing to one pathway of Rac1-mediated COX-2 expression Activated Rac1 GTPase translocates protein phosphatase 5 to the cell membrane and stimulates phosphatase activity in vitro ErbB2 directly activates the exchange factor Dock7 to promote Schwann cell migration.P21-activated kinase 1: convergence point in PDGF- and LPA-stimulated collagen matrix contraction by human fibroblasts Control of Dendritic Spine Morphological and Functional Plasticity by Small GTPases The Rac1 hypervariable region in targeting and signaling: a tail of many stories A RAC/CDC-42-independent GIT/PIX/PAK signaling pathway mediates cell migration in C. elegans Stretching morphogenesis of the roof plate and formation of the central canal Phosphorylation of tyrosine 285 of PAK1 facilitates βPIX/GIT1 binding and adhesion turnover Crystal Structures of the p21-Activated Kinases PAK4, PAK5, and PAK6 Reveal Catalytic Domain Plasticity of Active Group II PAKs Upregulation of p21-activated Kinase 6 in rat brain cortex after traumatic brain injury JAK2 tyrosine kinase phosphorylates PAK1 and regulates PAK1 activity and functions PAK1 is a novel cardiac protective signaling molecule Identification of p122RhoGAP (deleted in liver cancer-1) Serine 322 as a substrate for protein kinase B and ribosomal S6 kinase in insulin-stimulated cells P21-activated protein kinase (PAK2)-mediated c-Jun phosphorylation at 5 threonine sites promotes cell transformation A preferred AMPK phosphorylation site adjacent to the inhibitory loop of cardiac and skeletal troponin I Dlc1 interaction with non-muscle myosin heavy chain II-A (Myh9) and Rac1 activation Dissecting activation of the PAK1 kinase at protrusions in living cells.p21-Activated kinases 1 and 3 control brain size through coordinating neuronal complexity and synaptic properties The Toca-1-N-WASP complex links filopodial formation to endocytosis Activation of Rac1-PI3K/Akt is required for epidermal growth factor-induced PAK1 activation and cell migration in MDA-MB-231 breast cancer cells.PAK1-Nck regulates cyclin D1 promoter activity in response to prolactin Increased smooth muscle cell activation and neointima formation in response to injury in AIF-1 transgenic mice Focal adhesion kinase as a regulator of cell tension in the progression of cancer.PAK kinase regulates Rac GTPase and is a potential target in human schwannomas p27(Kip1) controls cytokinesis via the regulation of citron kinase activation.Oxidized LDL/CD36 interaction induces loss of cell polarity and inhibits macrophage locomotion.Coordination of Rho family GTPase activities to orchestrate cytoskeleton responses during cell wound repair.PDK1-mediated activation of MRCKα regulates directional cell migration and lamellipodia retraction.Natural products active in aberrant c-Kit signaling.Apical accumulation of Rho in the neural plate is important for neural plate cell shape change and neural tube formation.Physcomitrella patens: a model to investigate the role of RAC/ROP GTPase signalling in tip growth.

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P2860

PAK and other Rho-associated kinases--effectors with surprisingly diverse mechanisms of regulation

http://www.wikidata.org/entity/Q35952627

description

2005 nî lūn-bûn

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

@zh-tw

2005年论文

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2005年论文

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2005年论文

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name

PAK and other Rho-associated k ...... verse mechanisms of regulation

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PAK and other Rho-associated k ...... verse mechanisms of regulation

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PAK and other Rho-associated k ...... verse mechanisms of regulation

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PAK and other Rho-associated k ...... verse mechanisms of regulation

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PAK and other Rho-associated k ...... verse mechanisms of regulation

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PAK and other Rho-associated k ...... verse mechanisms of regulation

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P1433

Biochemical Journal

P1476

PAK and other Rho-associated k ...... verse mechanisms of regulation

@en

P2093

Ed Manser

http://www.w3.org/2001/XMLSchema#string

Zhou-shen Zhao

http://www.w3.org/2001/XMLSchema#string

P2860

Citron rho-interacting kinase, a novel tissue-specific ser/thr kinase encompassing the Rho-Rac-binding protein Citron

PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia

Dimerization via tandem leucine zippers is essential for the activation of the mitogen-activated protein kinase kinase kinase, MLK-3

Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase

Regulation of epidermal growth factor receptor traffic by the small GTPase rhoB

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1

Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop

Phosphorylation of myosin light chain kinase by p21-activated kinase PAK2

Phosphorylation of protein kinase N by phosphoinositide-dependent protein kinase-1 mediates insulin signals to the actin cytoskeleton

P304

201-214

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P31

scholarly article

P356

10.1042/BJ20041638

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P433

Pt 2

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P478

386

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2005-03-01T00:00:00Z

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15548136

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1134783

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