Oxygen sensing and HIF-1 activation does not require an active mitochondrial respiratory chain electron-transfer pathway.
about
Oxidative stress in cancer and fibrosis: Opportunity for therapeutic intervention with antioxidant compounds, enzymes, and nanoparticlesHypoxia-inducible factor-1-mediated expression of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) gene. Its possible role in the Warburg effectCarboxyl-terminal transactivation activity of hypoxia-inducible factor 1 alpha is governed by a von Hippel-Lindau protein-independent, hydroxylation-regulated association with p300/CBP.Hypoxia-inducible factors in the kidneyA Fenton reaction at the endoplasmic reticulum is involved in the redox control of hypoxia-inducible gene expression.Exposure of yeast cells to anoxia induces transient oxidative stress. Implications for the induction of hypoxic genes.The Drosophila mitochondrial ribosomal protein mRpL12 is required for Cyclin D/Cdk4-driven growthHIF-independent regulation of thioredoxin reductase 1 contributes to the high levels of reactive oxygen species induced by hypoxia.Signal transduction by mitochondrial oxidants.Erythropoietin after a century of research: younger than ever.Oxygen Sensing, Cardiac Ischemia, HIF-1α and Some Emerging ConceptsThe oxygen sensing signal cascade under the influence of reactive oxygen species.Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activationHypoxia Up-Regulates Galectin-3 in Mammary Tumor Progression and Metastasis.Oxidative stress in the systemic and cellular responses to intermittent hypoxia.Suppressors of superoxide production from mitochondrial complex IIIOxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia.Redox regulation of the hypoxia-inducible factor.Exogenous low dose hydrogen peroxide increases hypoxia-inducible factor-1alpha protein expression and induces preconditioning protection against ischemia in primary cortical neurons.Reactive oxygen species and cellular oxygen sensingReactive oxygen species-independent oxidation of thioredoxin in hypoxia: inactivation of ribonucleotide reductase and redox-mediated checkpoint control.Regulation of HIF-1α activity by overexpression of thioredoxin is independent of thioredoxin reductase statusRole of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia.Mechanisms associated with mitochondrial-generated reactive oxygen species in cancer.Molecular aspects of renal cell carcinoma: a review.Induction of vascular endothelial growth factor expression and hypoxia-inducible factor 1alpha protein by the oxidative stressor arsenite.Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment.c-Jun and hypoxia-inducible factor 1 functionally cooperate in hypoxia-induced gene transcription.Transcriptional Regulation of SDHa flavoprotein by nuclear respiratory factor-1 prevents pseudo-hypoxia in aerobic cardiac cells.Induction of HIF-2alpha is dependent on mitochondrial O2 consumption in an O2-sensitive adrenomedullary chromaffin cell line.Reactive oxygen species stabilize hypoxia-inducible factor-1 alpha protein and stimulate transcriptional activity via AMP-activated protein kinase in DU145 human prostate cancer cells.Detection of reactive oxygen species via endogenous oxidative pentose phosphate cycle activity in response to oxygen concentration: implications for the mechanism of HIF-1alpha stabilization under moderate hypoxia.Regulation of hypoxia-inducible factor-1alpha by nitric oxide through mitochondria-dependent and -independent pathways.Three autocrine feedback loops determine HIF1 alpha expression in chronic hypoxia.Hypoxic but not anoxic stabilization of HIF-1alpha requires mitochondrial reactive oxygen species.Lack of evidence for the involvement of the phosphoinositide 3-kinase/Akt pathway in the activation of hypoxia-inducible factors by low oxygen tension.A protective role for HIF-1 in response to redox manipulation and glucose deprivation: implications for tumorigenesis.Reactive oxygen species regulate hypoxia-inducible factor 1alpha differentially in cancer and ischemiaInsulin and hypoxia share common target genes but not the hypoxia-inducible factor-1alpha.Hypoxia promotes stem cell-like phenotype in multiple myeloma cells.
P2860
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P2860
Oxygen sensing and HIF-1 activation does not require an active mitochondrial respiratory chain electron-transfer pathway.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Oxygen sensing and HIF-1 activ ...... ain electron-transfer pathway.
@ast
Oxygen sensing and HIF-1 activ ...... ain electron-transfer pathway.
@en
type
label
Oxygen sensing and HIF-1 activ ...... ain electron-transfer pathway.
@ast
Oxygen sensing and HIF-1 activ ...... ain electron-transfer pathway.
@en
prefLabel
Oxygen sensing and HIF-1 activ ...... ain electron-transfer pathway.
@ast
Oxygen sensing and HIF-1 activ ...... ain electron-transfer pathway.
@en
P2093
P2860
P356
P1476
Oxygen sensing and HIF-1 activ ...... hain electron-transfer pathway
@en
P2093
P2860
P304
21995-21998
P356
10.1074/JBC.C100177200
P407
P577
2001-05-07T00:00:00Z