Expression of human kinase suppressor of Ras 2 (hKSR-2) gene in HL60 leukemia cells is directly upregulated by 1,25-dihydroxyvitamin D(3) and is required for optimal cell differentiation
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The Potential of Vitamin D-Regulated Intracellular Signaling Pathways as Targets for Myeloid Leukemia TherapyhKSR-2, a vitamin D-regulated gene, inhibits apoptosis in arabinocytosine-treated HL60 leukemia cellsInduction of differentiation of human leukemia cells by combinations of COX inhibitors and 1,25-dihydroxyvitamin D3 involves Raf1 but not Erk 1/2 signaling.Vitamin D3-driven signals for myeloid cell differentiation--implications for differentiation therapy1,25-dihydroxyvitamin D3 enhances the apoptotic activity of MDM2 antagonist nutlin-3a in acute myeloid leukemia cells expressing wild-type p53.MicroRNA-32 upregulation by 1,25-dihydroxyvitamin D3 in human myeloid leukemia cells leads to Bim targeting and inhibition of AraC-induced apoptosis.Inhibition of Cot1/Tlp2 oncogene in AML cells reduces ERK5 activation and up-regulates p27Kip1 concomitant with enhancement of differentiation and cell cycle arrest induced by silibinin and 1,25-dihydroxyvitamin D(3).Gene expression profiles in human and mouse primary cells provide new insights into the differential actions of vitamin D3 metabolites.Inhibitors for the Vitamin D Receptor-Coregulator Interaction.Expression of MAP3 kinase COT1 is up-regulated by 1,25-dihydroxyvitamin D3 in parallel with activated c-jun during differentiation of human myeloid leukemia cells.Dual role of hematopoietic progenitor kinase 1 (HPK1) as a positive regulator of 1α,25-dihydroxyvitamin D-induced differentiation and cell cycle arrest of AML cells and as a mediator of vitamin D resistanceOncoprotein Cot1 represses kinase suppressors of Ras1/2 and 1,25-dihydroxyvitamin D3-induced differentiation of human acute myeloid leukemia cells.DNA Repair in Despair-Vitamin D Is Not Fair.Differential localization of A-Raf regulates MST2-mediated apoptosis during epithelial differentiationSpatial regulation of ARAF controls the MST2-Hippo pathway.
P2860
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P2860
Expression of human kinase suppressor of Ras 2 (hKSR-2) gene in HL60 leukemia cells is directly upregulated by 1,25-dihydroxyvitamin D(3) and is required for optimal cell differentiation
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Expression of human kinase sup ...... r optimal cell differentiation
@ast
Expression of human kinase sup ...... r optimal cell differentiation
@en
type
label
Expression of human kinase sup ...... r optimal cell differentiation
@ast
Expression of human kinase sup ...... r optimal cell differentiation
@en
prefLabel
Expression of human kinase sup ...... r optimal cell differentiation
@ast
Expression of human kinase sup ...... r optimal cell differentiation
@en
P2093
P2860
P1476
Expression of human kinase sup ...... r optimal cell differentiation
@en
P2093
George P Studzinski
Tian-Tian Wang
Xuening Wang
P2860
P304
P356
10.1016/J.YEXCR.2007.05.021
P407
P577
2007-05-31T00:00:00Z