Notch2 signaling induces apoptosis and inhibits human MDA-MB-231 xenograft growth. - Wikidata - wikimedia - TriplyDB

Notch2 signaling induces apoptosis and inhibits human MDA-MB-231 xenograft growth.

Notch2 signaling induces apoptosis and inhibits human MDA-MB-231 xenograft growth.

http://www.wikidata.org/entity/Q35963167

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Hairy-related transcription factors inhibit Notch-induced smooth muscle alpha-actin expression by interfering with Notch intracellular domain/CBF-1 complex interaction with the CBF-1-binding site The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer NOTCH receptors in gastric and other gastrointestinal cancers: oncogenes or tumor suppressors?Γ-secretase components as predictors of breast cancer outcome A synthetic triterpenoid CDDO-Im inhibits tumorsphere formation by regulating stem cell signaling pathways in triple-negative breast cancer Notch2 signaling sensitizes endothelial cells to apoptosis by negatively regulating the key protective molecule survivin.Annonaceous acetogenins mediated up-regulation of Notch2 exerts growth inhibition in human gastric cancer cells in vitro.Gliotoxin Targets Nuclear NOTCH2 in Human Solid Tumor Derived Cell Lines In Vitro and Inhibits Melanoma Growth in Xenograft Mouse Model.Sonic hedgehog acts as a negative regulator of {beta}-catenin signaling in the adult tongue epithelium.Notch activation by phenethyl isothiocyanate attenuates its inhibitory effect on prostate cancer cell migration Notch2 activation is protective against anticancer effects of zerumbone in human breast cancer cells Notch activation is dispensable for D, L-sulforaphane-mediated inhibition of human prostate cancer cell migration.Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1)Notch-EGFR/HER2 Bidirectional Crosstalk in Breast Cancer Role of Notch and its oncogenic signaling crosstalk in breast cancer.Notch signaling proteins: legitimate targets for cancer therapy.The role of polycomb group protein Bmi-1 and Notch4 in breast cancer stem cell inhibition by benzyl isothiocyanate.Notch2 genetic fate mapping reveals two previously unrecognized mammary epithelial lineages.Notch signaling as a therapeutic target for breast cancer treatment?NOTCH-1 and NOTCH-4 are novel gene targets of PEA3 in breast cancer: novel therapeutic implications.A novel animal model for locally advanced breast cancer.MiR-34b is associated with clinical outcome in triple-negative breast cancer patients Notch2 regulates matrix metallopeptidase 9 via PI3K/AKT signaling in human gastric carcinoma cell MKN-45 Soluble forms of the Notch ligands Delta1 and Jagged1 promote in vivo tumorigenicity in NIH3T3 fibroblasts with distinct phenotypes Withaferin A inhibits in vivo growth of breast cancer cells accelerated by Notch2 knockdown.Does treatment of split-thickness skin grafts with negative-pressure wound therapy improve tissue markers of wound healing in a porcine experimental model?Gamma secretase inhibitors of Notch signaling Increased LEF1 expression and decreased Notch2 expression are strong predictors of poor outcomes in colorectal cancer patients.Development and cancer: at the crossroads of Nodal and Notch signaling.The cytotoxicity of gamma-secretase inhibitor I to breast cancer cells is mediated by proteasome inhibition, not by gamma-secretase inhibition.Common profiles of Notch signaling differentiate disease-free survival in luminal type A and triple negative breast cancer.Targeting Notch to target cancer stem cells.Therapeutic modulation of Notch signalling--are we there yet?Significance of glycosylation in Notch signaling.Enhanced Directional Migration of Cancer Stem Cells in 3D Aligned Collagen Matrices.In vitro effects of phenytoin and DAPT on MDA-MB-231 breast cancer cells.Effects of Notch-1 down-regulation on malignant behaviors of breast cancer stem cells.Notch2-induced COX-2 expression enhancing gastric cancer progression.Prognostic values of Notch receptors in breast cancer.Opposing actions of endocannabinoids on cholangiocarcinoma growth is via the differential activation of Notch signaling.

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P2860

Notch2 signaling induces apoptosis and inhibits human MDA-MB-231 xenograft growth.

http://www.wikidata.org/entity/Q35963167

description

2007 nî lūn-bûn

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

Notch2 signaling induces apoptosis and inhibits human MDA-MB-231 xenograft growth.

@ast

Notch2 signaling induces apoptosis and inhibits human MDA-MB-231 xenograft growth.

@en

type

label

Notch2 signaling induces apoptosis and inhibits human MDA-MB-231 xenograft growth.

@ast

Notch2 signaling induces apoptosis and inhibits human MDA-MB-231 xenograft growth.

@en

prefLabel

Notch2 signaling induces apoptosis and inhibits human MDA-MB-231 xenograft growth.

@ast

Notch2 signaling induces apoptosis and inhibits human MDA-MB-231 xenograft growth.

@en

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AJPATH.2007.061029

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The American Journal of Pathology

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Notch2 signaling induces apoptosis and inhibits human MDA-MB-231 xenograft growth.

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Alexis Lincoln

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Carla Mouta-Bellum

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Christina Cinelli

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Christine F O'Neill

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Jessica Toher

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Lucy Liaw

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Robert E Friesel

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Robert J Nadeau

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Ruth León

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Sumithra Urs

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P2860

Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells

Notch signaling induces cell cycle arrest in small cell lung cancer cells

Soluble Jagged 1 represses the function of its transmembrane form to induce the formation of the Src-dependent chord-like phenotype

Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism

Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene

Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis

MMTV-induced mammary tumorigenesis: gene discovery, progression to malignancy and cellular pathways

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

HES and HERP families: multiple effectors of the Notch signaling pathway

ONCOMINE: a cancer microarray database and integrated data-mining platform

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